Nucleoporin p58/p45 (NUP58) is a 599-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9BVL2.
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The mean pLDDT of this model is 55.7 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 20% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 61% |
What pLDDT means and how to read it
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane
Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUP58. Interacts with NUTF2. Interacts with SRP1-alpha and Importin p97 proteins when they are together, but not with SRP1-alpha protein alone (By similarity)
Nucleus, nuclear pore complex, Nucleus membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4JO7 | X-ray | 1.75 Å | A/C/E/G=341-428 |
| 4JQ5 | X-ray | 2.2 Å | A/B/C/D/E/F/G/H/I/J/K/L=341-425 |
| 4JO9 | X-ray | 2.5 Å | B=341-426 |
| 7R5K | EM | 12.0 Å | I0/I1/I2/I3=1-599 |
| 5IJN | EM | 21.4 Å | G/M/S/Y=1-599 |
| 5IJO | EM | 21.4 Å | G/M/S/Y=1-599 |
| 7PER | EM | 35.0 Å | G/M/S/Y=1-599 |
| 7R5J | EM | 50.0 Å | I0/I1/I2/I3=1-599 |
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