Q9CWE6: Oocyte-expressed protein homolog (Ooep)

Oocyte-expressed protein homolog (Ooep) is a 164-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9CWE6.

Gene
Ooep
Organism
Mus musculus
Length
164 residues
Mean pLDDT
79.3
Model
AF-Q9CWE6-F1 v6
Model created
1 Aug 2025
PDB structures
9

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Model confidence (pLDDT)

The mean pLDDT of this model is 79.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate51%
70 to 90Confident: backbone generally right18%
50 to 70Low: treat with caution21%
Below 50Very low: often disordered regions10%

What pLDDT means and how to read it

Function

Component of the subcortical maternal complex (SCMC), a multiprotein complex that plays a key role in early embryonic development (PubMed:18804437, PubMed:25208553, PubMed:37922900). The SCMC complex is a structural constituent of cytoplasmic lattices, which consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos (PubMed:31575650, PubMed:37922900, PubMed:41845018, PubMed:41917274, PubMed:41986725). They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins, cytoskeletal tubulins and proteins controlling epigenetic reprogramming of the preimplantation embryo, in a poised but restrained state, regulating…

Subunit structure

Component of the subcortical maternal complex (SCMC), at least composed of NLRP5, KHDC3, OOEP and TLE6 (PubMed:18804437, PubMed:28992324, PubMed:37922900, PubMed:38177687). Within the complex, interacts with NLRP5, KHDC3 and TLE6 (PubMed:18804437, PubMed:31575650). Core component of cytoplasmic lattices, at least composed of PADI6, NLRP4F, NLRP5, NLRP14, TLE6, KHDC3, OOEP and ZBED3…

Subcellular location

Cytoplasm, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8H96EM2.78 ÅC=1-164
8H94EM2.9 ÅC=1-164
8XI3EM3.0 ÅC=1-164
9L4JEM3.0 ÅD=26-114
8H93EM3.01 ÅC/F=1-164
8H95EM3.38 ÅC=1-164
9XRLEM3.74 ÅAH/AI/AJ/AT/e/g=28-142
9SFPEM4.2 ÅK/L=25-145
9W2MEM4.2 ÅC/H/c/h=21-144

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