1EGL: Eglin C

The solution structure of eglin C based on measurements of many noes and coupling constants and its comparison with X-ray structures. Determined by solution NMR. Released 31 Jan 1994.

Method: Solution NMR
Organism: Hirudo medicinalis
Chains: 1
Atoms: 576
Mol. weight: 8.1 kDa
Released: 31 Jan 1994

Explore 1EGL in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1EGL contains 1 α-helix and 7 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 7 β-strands

Element	Residues	Length	Sheet
β-strand	9	1	1
β-strand	17	1	2
α-helix	18-28	11
β-strand	33-38	6	1
β-strand	51-56	6	1
β-strand	57	1	2
β-strand	62	1	2
β-strand	68-69	2	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Eglin C	A	protein	70	Hirudo medicinalis	P01051 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1EGL_1 EGLIN C (chains A)
TEFGSELKSFPEVVGKTVDQAREYFTLHYPQYDVYFLPEGSPVTLDLRYNRVRVFYNPGT
NVVNHVPHVG

Primary citation

The solution structure of eglin c based on measurements of many NOEs and coupling constants and its comparison with X-ray structures. Hyberts, S.G., Goldberg, M.S., Havel, T.F. et al. Protein Sci (1992) 1:736-751. PubMed

Other PDB entries of the same protein (UniProt P01051 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1CSE 1.2 Å, The high-resolution X-ray crystal structure of the complex formed between subtilisin…
4B2B 1.36 Å, Structure of the factor Xa-like trypsin variant triple-Ala (TGPA) in complex with eglin C
4B2C 1.43 Å, Structure of the factor Xa-like trypsin variant triple-Ala (TPA) in complex with eglin C
4B1T 1.78 Å, Structure of the factor Xa-like trypsin variant triple-Ala (TA) in complex with eglin C
2SEC 1.8 Å, Structural comparison of two serine proteinase-protein inhibitor complexes.…
4B2A 1.89 Å, Structure of the factor Xa-like trypsin variant triple-Ala (TGA) in complex with eglin C
4H4F 1.9 Å, Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo…
2TEC 1.98 Å, Molecular dynamics refinement of a thermitase-eglin-C complex at 1.98 Å resolution and…
1ACB 2.0 Å, Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin C complex at 2.0…
1EGP 2.0 Å, Proteinase inhibitor eglin C with hydrolysed reactive center
1MEE 2.0 Å, The complex between the subtilisin from a mesophilic bacterium and the leech inhibitor…
3TEC 2.0 Å, Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5 and 100 mm…

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