1FNA: Fibronectin cell-adhesion module type III-10

Crystal structure of the tenth type III cell adhesion module of human fibronectin. Determined by X-ray diffraction at 1.8 Å resolution. Released 30 Apr 1994.

Method: X-ray diffraction
Resolution: 1.8 Å
Organism: Homo sapiens
Chains: 1
Atoms: 675
Mol. weight: 9.69 kDa
Released: 30 Apr 1994

Explore 1FNA in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1FNA contains 3 α-helices and 7 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	9-13	5	1
β-strand	18-21	4	1
β-strand	31-38	8	2
α-helix	44-45	2
β-strand	46-51	6	2
β-strand	56-59	4	1
α-helix	62-63	2
β-strand	67-75	9	2
β-strand	88-93	6	2
α-helix	94-95	2

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Fibronectin cell-adhesion module type III-10	A	protein	91	Homo sapiens	P02751 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1FNA_1 FIBRONECTIN CELL-ADHESION MODULE TYPE III-10 (chains A)
RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG
VDYTITVYAVTGRGDSPASSKPISINYRTEI

Primary citation

Crystal structure of the tenth type III cell adhesion module of human fibronectin. Dickinson, C.D., Veerapandian, B., Dai, X.P. et al. J Mol Biol (1994) 236:1079-1092. DOI 10.1016/0022-2836(94)90013-2 · PubMed

Other PDB entries of the same protein (UniProt P02751 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2CG7 1.2 Å, Second and third fibronectin type I module pair (crystal form II).
4LXO 1.42 Å, Crystal structure of 9,10Fn3-elegantin chimera
5DC4 1.48 Å, Crystal structure of monobody AS25/ABL1 SH2 domain complex, crystal a
2CG6 1.55 Å, Second and third fibronectin type I module pair (crystal form I).
5DC9 1.56 Å, Crystal structure of monobody AS25/ABL1 SH2 domain complex, crystal B
5N48 1.6 Å, Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin
3CAL 1.7 Å, Crystal structure of the second and third fibronectin F1 modules in complex with a…
3ZRZ 1.7 Å, Crystal structure of the second and third fibronectin F1 modules in complex with a…
6MFA 1.75 Å, Fragment of human fibronectin containing the 4th-7th type III domains
2RKY 1.8 Å, Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a…
4PZ5 1.96 Å, Crystal structure of the second and third fibronectin F1 modules in complex with a…
1FNF 2.0 Å, Fragment of human fibronectin encompassing type-III repeats 7 through 10

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