1RJ2: DH/PH fragment of Dbs without bound GTPase

Crystal structure of the DH/PH fragment of Dbs without bound GTPase. Determined by X-ray diffraction at 3.0 Å resolution. Released 29 Jun 2004.

Method

X-ray diffraction

Resolution

3.0 Å

Organism

Mus musculus

Chains

4

Atoms

10,370

Mol. weight

164.88 kDa

Released

29 Jun 2004

Explore 1RJ2 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1RJ2 contains 74 α-helices and 35 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 19 helices, 8 β-strands

Molecules and chains

>1RJ2_1 Guanine nucleotide exchange factor DBS [Fragment] (chains A, D, G, J)
MGEEEESLAILRRHVMNELLDTERAYVEELLCVLEGYAAEMDNPLMAHLISTGLQNKKNI
LFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLERMEEFQIYEKYCQNKPRSESLWRQ
CSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSKHCEGAEDLQEALSS
ILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKPMQR
HLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYNARE
EVYIIQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSHSLPHHHHHH

Primary citation

Crystal structure of the DH/PH fragment of Dbs without bound GTPase. Worthylake, D.K., Rossman, K.L., Sondek, J. Structure (2004) 12:1078-1086. DOI 10.1016/j.str.2004.03.021 · PubMed

Related structures

Other PDB entries of the same protein (UniProt Q64096 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 1KZ7 2.4 Å, Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental…
• 1KZG 2.6 Å, DbsCdc42(Y889F)
• 1LB1 2.81 Å, Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA

Browse structure collections

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