1SY9: Calmodulin

Structure of calmodulin complexed with a fragment of the olfactory CNG channel. Determined by solution NMR. Released 12 Apr 2005.

Method: Solution NMR
Organism: Xenopus laevis
Chains: 2
Atoms: 1,331
Mol. weight: 20.15 kDa
Ligands: CA
Released: 12 Apr 2005

Explore 1SY9 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1SY9 contains 9 α-helices and 4 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 8 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	6-19	14
β-strand	27	1	1
α-helix	29-39	11
α-helix	45-55	11
β-strand	63	1	1
α-helix	65-78	14
α-helix	81-92	12
β-strand	99	1	2
α-helix	102-112	11
α-helix	118-128	11
β-strand	137	1	2
α-helix	138-145	8

Chain B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	157-172	16

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Calmodulin	A	protein	148	Xenopus laevis	P0DP33 (AlphaFold model)
Cyclic-nucleotide-gated olfactory channel	B	protein	26		Q03041 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1SY9_1 CALMODULIN (chains A)
ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN
GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEE
VDEMIREADIDGDGQVNYEEFVQMMTAK

Sequence of entity 2 (B), FASTA

>1SY9_2 Cyclic-nucleotide-gated olfactory channel (chains B)
QQRRGGFRRIARLVGVLREWAYRNFR

Ligands and cofactors

ID	Name	Formula	Copies
CA	Calcium ion	Ca	4

Primary citation

Structure of calmodulin complexed with an olfactory CNG channel fragment and role of the central linker: residual dipolar couplings to evaluate calmodulin binding modes outside the kinase family. Contessa, G.M., Orsale, M., Melino, S. et al. J Biomol NMR (2005) 31:185-199. DOI 10.1007/s10858-005-0165-1 · PubMed

Other PDB entries of the same protein (UniProt P0DP33 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1IQ5 1.8 Å, Calmodulin/nematode CA2+/Calmodulin dependent kinase kinase fragment
2COL 2.2 Å, Crystal structure analysis of CyaA/C-Cam with Pyrophosphate
4R8G 3.5 Å, Crystal Structure of Myosin-1c tail in complex with Calmodulin
1Y0V 3.6 Å, Crystal structure of anthrax edema factor (EF) in complex with calmodulin and…
1CFC Calcium-free calmodulin
1CFD Calcium-free calmodulin
1CFF NMR solution structure of a complex of calmodulin with a binding peptide of the CA2+-pump
1CKK Calmodulin/rat CA2+/CALMODULIN dependent protein kinase fragment
1DMO Calmodulin, NMR, 30 structures
1F70 Refined solution structure of calmodulin N-terminal domain
1F71 Refined solution structure of calmodulin C-terminal domain
1MUX Solution NMR structure of calmodulin/w-7 complex: the basis of diversity in molecular…

Browse structure collections

About this viewer

MolViewer shows 1SY9 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.