1UDG: Uracil-DNA glycosylase

The structural basis of specific base excision repair by uracil-DNA glycosylase. Determined by X-ray diffraction at 1.75 Å resolution. Released 29 Jan 1996.

Method: X-ray diffraction
Resolution: 1.75 Å
Organism: Herpes simplex virus (type 1 / strain 17)
Chains: 1
Atoms: 1,957
Mol. weight: 27.56 kDa
Released: 29 Jan 1996

Explore 1UDG in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1UDG contains 13 α-helices and 7 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 13 helices, 7 β-strands

Element	Residues	Length	Sheet
α-helix	18-26	9
α-helix	30-32	3
α-helix	33-40	8
α-helix	43-58	16
β-strand	61-62	2	1
α-helix	71-74	4
α-helix	77-79	3
β-strand	82-86	5	2
α-helix	111-123	13
α-helix	136-140	5
β-strand	143-147	5	2
β-strand	152-153	2	1
β-strand	156	1	1
α-helix	165-179	15
β-strand	184-188	5	2
α-helix	190-195	6
β-strand	204-208	5	2
α-helix	219-221	3
α-helix	224-233	10
α-helix	237-240	4

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Uracil-DNA glycosylase	A	protein	244	Herpes simplex virus (type 1 / strain 17)	P10186

Sequence of entity 1 (A), FASTA

>1UDG_1 URACIL-DNA GLYCOSYLASE (chains A)
MDLTNGGVSPAATSAPLDWTTFRRVFLIDDAWRPLMEPELANPLTAHLLAEYNRRCQTEE
VLPPREDVFSWTRYCTPDEVRVVIIGQDPYHHPGQAHGLAFSVRANVPPPPSLRNVLAAV
KNCYPEARMSGHGCLEKWARDGVLLLNTTLTVKRGAAASHSRIGWDRFVGGVIRRLAARR
PGLVFMLWGTHAQNAIRPDPRVHCVLKFSHPSPLSKVPFGTCQHFLVANRYLETRSISPI
DWSV

Primary citation

The structural basis of specific base-excision repair by uracil-DNA glycosylase. Savva, R., McAuley-Hecht, K., Brown, T. et al. Nature (1995) 373:487-493. DOI 10.1038/373487a0 · PubMed

Other PDB entries of the same protein (UniProt P10186), best resolution first:

1UDH 1.75 Å, The structural basis of specific base excision repair by uracil-DNA glycosylase
1LAU 1.8 Å, Uracil-DNA glycosylase
2C53 1.8 Å, A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1
5AYS 2.09 Å, Crystal structure of SAUGI/HSV UDG complex
2C56 2.1 Å, A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1
4L5N 2.16 Å, Crystallographic Structure of HHV-1 Uracil-DNA Glycosylase complexed with the Bacillus…
1UDI 2.7 Å, Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil…

Browse structure collections

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