2MUR: Human FAAP20 UBZ-Ubiquitin Complex

Solution Structure of the Human FAAP20 UBZ-Ubiquitin Complex. Determined by solution NMR. Released 3 Dec 2014.

Method: Solution NMR
Organism: Homo sapiens
Chains: 2
Atoms: 953
Mol. weight: 13.72 kDa
Ligands: ZN
Released: 3 Dec 2014

Explore 2MUR in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2MUR contains 4 α-helices and 9 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 2 helices, 2 β-strands

Element	Residues	Length	Sheet
β-strand	10-11	2	1
β-strand	16-17	2	1
α-helix	18-19	2
α-helix	24-37	14

Chain B: 2 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	101-106	6	2
β-strand	112-117	6	2
β-strand	122	1	3
α-helix	123-134	12
β-strand	141-145	5	2
β-strand	148-150	3	2
β-strand	155	1	3
α-helix	157-159	3
β-strand	166-171	6	2

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Fanconi anemia-associated protein of 20 kDa	A	protein	44	Homo sapiens	Q6NZ36 (AlphaFold model)
Ubiquitin	B	protein	78	Homo sapiens	P62987 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>2MUR_1 Fanconi anemia-associated protein of 20 kDa (chains A)
SHMGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW

Sequence of entity 2 (B), FASTA

>2MUR_2 Ubiquitin (chains B)
SHMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD
YNIQKESTLHLVLRLRGG

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	1

Primary citation

Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. Wojtaszek, J.L., Wang, S., Kim, H. et al. Nucleic Acids Res (2014) 42:13997-14005. DOI 10.1093/nar/gku1153 · PubMed

Other PDB entries of the same protein (UniProt Q6NZ36 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3WWQ 1.9 Å, Crystal structure of FAAP20 UBZ domain in complex with Lys63-linked diubiquitin
2MUQ Solution Structure of the Human FAAP20 UBZ

Browse structure collections

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