3CYI: Human Sulfiredoxin

Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ATP:Mg2+. Determined by X-ray diffraction at 1.8 Å resolution. Released 1 Jul 2008.

Method
X-ray diffraction
Resolution
1.8 Å
Organism
Homo sapiens
Chains
1
Atoms
929
Mol. weight
12.55 kDa
Ligands
MG, ATP
Released
1 Jul 2008

Explore 3CYI in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3CYI contains 7 α-helices and 5 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 7 helices, 5 β-strands

ElementResiduesLengthSheet
β-strand39-4571
α-helix46-483
β-strand49-5021
α-helix59-7113
α-helix73-753
α-helix77-782
β-strand79-8571
β-strand91-9441
α-helix99-1079
β-strand112-12091
α-helix122-1298
α-helix130-1323

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Sulfiredoxin-1Aprotein110Homo sapiensQ9BYN0 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>3CYI_1 Sulfiredoxin-1 (chains A)
GPHMSIHSGRIAAVHNVPLSVLIRPLPSVLDPAKVQSLVDTIREDPDSVPPIDVLWIKGA
QGGDYFYSFGGSHRYAAYQQLQRETIPAKLVQSTLSDLRVYLGASTPDLQ

Ligands and cofactors

IDNameFormulaCopies
MGMagnesium ionMg1
ATPAdenosine-5'-triphosphateC10 H16 N5 O13 P31

Primary citation

Reduction of Cysteine Sulfinic Acid in Peroxiredoxin by Sulfiredoxin Proceeds Directly through a Sulfinic Phosphoryl Ester Intermediate. Jonsson, T.J., Murray, M.S., Johnson, L.C. et al. J Biol Chem (2008) 283:23846-23851. DOI 10.1074/jbc.M803244200 · PubMed

Other PDB entries of the same protein (UniProt Q9BYN0 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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