3U1C: Tropomyosin alpha-1 chain

Anti-parallel dimer of N-terminal 98-aa fragment of smooth muscle tropomyosin alpha. Determined by X-ray diffraction at 1.8 Å resolution. Released 23 Nov 2011.

Method: X-ray diffraction
Resolution: 1.8 Å
Organism: Gallus gallus
Chains: 2
Atoms: 1,823
Mol. weight: 23.19 kDa
Released: 23 Nov 2011

Explore 3U1C in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3U1C contains 2 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	0-96	97

Chain B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	3-95	93

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Tropomyosin alpha-1 chain	A, B	protein	101	Gallus gallus	P04268 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>3U1C_1 Tropomyosin alpha-1 chain (chains A, B)
AGHMDAIKKKMQMLKLDKENALDRAEQAEADKKAAEERSKQLEDDIVQLEKQLRVTEDSR
DQVLEELHKSEDSLLFAEENAAKAESEVASLNRRIQLVEEE

Primary citation

Structural analysis of smooth muscle tropomyosin alpha and beta isoforms. Rao, J.N., Rivera-Santiago, R., Li, X.E. et al. J Biol Chem (2012) 287:3165-3174. DOI 10.1074/jbc.M111.307330 · PubMed

Other PDB entries of the same protein (UniProt P04268 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1IC2 2.0 Å, Deciphering the design of the tropomyosin molecule
3U1A 2.0 Å, N-terminal 81-aa fragment of smooth muscle tropomyosin alpha
3MTU 2.1 Å, Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle
3MUD 2.2 Å, Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle

Browse structure collections

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