5NFD: Antiparallel monomeric coiled coil of Kif21A

Antiparallel monomeric coiled coil of Kif21A. Determined by X-ray diffraction at 2.18 Å resolution. Released 2 May 2018.

Method: X-ray diffraction
Resolution: 2.18 Å
Organism: Homo sapiens
Chains: 2
Atoms: 1,344
Mol. weight: 18.93 kDa
Released: 2 May 2018

Explore 5NFD in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5NFD contains 4 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 2 helices, 0 β-strands

Element	Residues	Length	Sheet
α-helix	5-39	35
α-helix	48-80	33

Chain B: 2 helices, 0 β-strands

Element	Residues	Length	Sheet
α-helix	5-41	37
α-helix	47-80	34

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Kinesin-like protein KIF21A	A, B	protein	82	Homo sapiens	Q7Z4S6 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>5NFD_1 Kinesin-like protein KIF21A (chains A, B)
GSMTISNMEADCNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTAN
IDYINDSISDCQANIMQMEEAK

Primary citation

Combinatorial use of disulfide bridges and native sulfur-SAD phasing for rapid structure determination of coiled-coils. Kraatz, S.H.W., Bianchi, S., Steinmetz, M.O. Biosci Rep (2018) 38. DOI 10.1042/BSR20181073 · PubMed

Other PDB entries of the same protein (UniProt Q7Z4S6 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7KLJ 1.52 Å, Crystal structure of the WD-repeat domain of human KIF21A
5YBU 1.89 Å, Structure of the KANK1 ankyrin domain in complex with KIF21A peptide
5YBV 2.12 Å, The structure of the KANK2 ankyrin domain with the KIF21A peptide
5D3A 2.5 Å, KIF21A regulatory coiled coil

Browse structure collections

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