5USN: Schizosaccharomyces pombe Pot1pC

Crystal Structure of Schizosaccharomyces pombe Pot1pC bound to ssRNA/ssDNA chimera (rGrGrUTACGGT). Determined by X-ray diffraction at 1.9 Å resolution. Released 18 Apr 2018.

Method
X-ray diffraction
Resolution
1.9 Å
Organism
Schizosaccharomyces pombe
Chains
2
Atoms
1,557
Mol. weight
19.81 kDa
Released
18 Apr 2018

Explore 5USN in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5USN contains 4 α-helices and 8 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 4 helices, 8 β-strands

ElementResiduesLengthSheet
α-helix8-103
β-strand16-28131
β-strand33-3861
β-strand4912
β-strand6312
β-strand67-7151
α-helix73-797
β-strand88-98111
β-strand104-10851
β-strand119-12351
α-helix128-1303
α-helix131-14212

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Protection of telomeres protein 1Aprotein141Schizosaccharomyces pombeO13988 (AlphaFold model)
1-3R_9mer dna/rna (5'-r(*gp*gp*u)-d(p*tp*ap*cp*gp*gp*t)-3')BNA-hybrid9Schizosaccharomyces pombe
Sequence of entity 1 (A), FASTA
>5USN_1 Protection of telomeres protein 1 (chains A)
DSFSLLSQITPHQRCSFYAQVIKTWYSDKNFTLYVTDYTENELFFPMSPYTSSSRWRGPF
GRFSIRCILWDEHDFYCRNYIKEGDYVVMKNVRTKIDHLGYLECILHGDSAKRYNMSIEK
VDSEEPELNEIKSRKRLYVQN
Sequence of entity 2 (B), FASTA
>5USN_2 1-3R_9mer DNA/RNA (5'-R(*GP*GP*U)-D(P*TP*AP*CP*GP*GP*T)-3') (chains B)
GGUTACGGT

Primary citation

Discrimination against RNA Backbones by a ssDNA Binding Protein. Lloyd, N.R., Wuttke, D.S. Structure (2018) 26:722-733.e2. DOI 10.1016/j.str.2018.03.016 · PubMed

Other PDB entries of the same protein (UniProt O13988 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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