Protection of telomeres protein 1 (pot1) is a 555-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O13988.
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The mean pLDDT of this model is 78.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 37% |
| 70 to 90 | Confident: backbone generally right | 38% |
| 50 to 70 | Low: treat with caution | 13% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Single-stranded telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang. It binds the consensus sequence 5'-GGTTAC-3'. Regulates telomerase and telomere length
Self-associates. Interacts with ccq1, poz1 and tpz1
Nucleus, Chromosome, telomere
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5USB | X-ray | 1.61 Å | A=199-337 |
| 4HIK | X-ray | 1.64 Å | A=198-339 |
| 4HIM | X-ray | 1.75 Å | A=198-339 |
| 4HIO | X-ray | 1.75 Å | A=198-339 |
| 4HJ7 | X-ray | 1.78 Å | A=198-339 |
| 4HID | X-ray | 1.82 Å | A=198-339 |
| 4HJ9 | X-ray | 1.85 Å | A=198-339 |
| 1QZG | X-ray | 1.9 Å | A/B=2-185 |
| 5USN | X-ray | 1.9 Å | A=199-339 |
| 5USO | X-ray | 2.0 Å | A=199-337 |
| 4HJ5 | X-ray | 2.04 Å | A=198-339 |
| 4HJ8 | X-ray | 2.04 Å | A=198-339 |
| 4HJA | X-ray | 2.1 Å | A=198-339 |
| 1QZH | X-ray | 2.4 Å | A/B/C/D/E/F=2-185 |
| 7CUI | X-ray | 2.6 Å | A/C=357-555 |
| 6BWY | X-ray | 2.9 Å | A/B/E/G=5-174 |
| 7CUH | X-ray | 3.0 Å | A=1-339 |
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