5ZYX: PDB entry 5ZYX

Solution NMR structure of K30 peptide in 10 mM dioctanoyl phosphatidylglycerol (D8PG). Determined by solution NMR. Released 12 Jun 2019.

Method: Solution NMR
Organism: Homo sapiens
Chains: 1
Atoms: 189
Mol. weight: 2.7 kDa
Released: 12 Jun 2019

Explore 5ZYX in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5ZYX contains 3 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	2-7	6
α-helix	9-12	4
α-helix	16-19	4

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Arg-trp-lys-arg-his-ile-ser-glu-gln-leu-arg-arg-arg-asp-arg-leu-gln-arg-gln-ala	A	protein	20	Homo sapiens	Q676U5 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>5ZYX_1 ARG-TRP-LYS-ARG-HIS-ILE-SER-GLU-GLN-LEU-ARG-ARG-ARG-ASP-ARG-LEU-GLN-ARG-GLN-ALA (chains A)
RWKRHISEQLRRRDRLQRQA

Primary citation

Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. Varnava, K.G., Mohid, S.A., Calligari, P. et al. Bioconjug Chem (2019) 30:1998-2010. DOI 10.1021/acs.bioconjchem.9b00290 · PubMed

Other PDB entries of the same protein (UniProt Q676U5 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7F69 1.5 Å, Crystal structure of WIPI2b in complex with ATG16L1
5NUV 1.55 Å, Structure of the WD40-domain of human ATG16L1
7XFR 1.76 Å, Crystal structure of WIPI2b in complex with the second site of ATG16L1
9JF2 1.76 Å, Crystal structure of GABARAPL1 in complex with ATG16L1
4NAW 2.19 Å, Crystal Structure of Human ATG12~ATG5-ATG16N in complex with a fragment of ATG3
4TQ0 2.7 Å, Crystal structure of human ATG5-ATG16N69
4GDK 2.7 Å, Crystal Structure of Human Atg12~Atg5 Conjugate in Complex with an N-terminal Fragment…
8ZQG 2.77 Å, Crystal structure of WIPI3 in complex with ATG16L1
4GDL 2.88 Å, Crystal Structure of Human Atg12~Atg5 Conjugate in Complex with an N-terminal Fragment…
5D7G 3.0 Å, Structure of human ATG5 E122D-ATG16L1 complex at 3.0 Angstroms
7W36 3.0 Å, Crystal structure of human Atg5 complexed with a stapled peptide
5NPV 3.1 Å, Structure of human ATG5-ATG16L1(ATG5BD) complex (I4)

Browse structure collections

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