6CEJ: 14mer fragment of the p21 protein
Solution structure of a 14mer fragment of the p21 protein. Determined by solution NMR. Released 4 Jul 2018.
- Method
- Solution NMR
- Organism
- Homo sapiens
- Chains
- 1
- Atoms
- 125
- Mol. weight
- 1.79 kDa
- Released
- 4 Jul 2018
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RCSB PDB
PDBe
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Cyclin-dependent kinase inhibitor 1 | A | protein | 14 | Homo sapiens | P38936 (AlphaFold model) |
Sequence of entity 1 (A), FASTA
>6CEJ_1 Cyclin-dependent kinase inhibitor 1 (chains A)
GRKRRQTSMTDFYH
Primary citation
Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Wegener, K.L., McGrath, A.E., Dixon, N.E. et al. Chemistry (2018) 24:11325-11331. DOI 10.1002/chem.201801734 · PubMed
Other PDB entries of the same protein (UniProt P38936 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 5E0U 1.93 Å, Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
- 2ZVV 2.0 Å, Crystal structure of Proliferating cellular nuclear antigen 1 and Short peptide from…
- 8GJF 2.0 Å, afupcna bound with peptide mimetic
- 4RJF 2.01 Å, Crystal structure of the human sliding clamp at 2.0 angstrom resolution
- 7KQ0 2.4 Å, PCNA bound to peptide mimetic
- 2ZVW 2.5 Å, Crystal structure of Proliferating cell nuclear antigen 2 and Short peptide from human P21
- 1AXC 2.6 Å, Human pcna
- 6CBI 2.75 Å, PCNA in complex with inhibitor
- 6P8H 3.19 Å, Crystal structure of CDK4 in complex with CyclinD1 and P21
- 7KQ1 3.3 Å, PCNA bound to truncated peptide mimetic
- 6CIV Lactam cyclised mimetic of a fragment of p21
- 6CIX Lactam cyclised mimetic of a fragment of p21
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