6JJX: KIBRA and Angiomotin complex

Crystal Structure of KIBRA and Angiomotin complex. Determined by X-ray diffraction at 2.0 Å resolution. Released 25 Sept 2019.

Method: X-ray diffraction
Resolution: 2.0 Å
Organisms: Mus musculus, Homo sapiens
Chains: 4
Atoms: 2,517
Mol. weight: 37.65 kDa
Released: 25 Sept 2019

Explore 6JJX in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6JJX contains 11 α-helices and 12 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 4 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	6-9	4
β-strand	12-16	5	1
β-strand	22-26	5	1
β-strand	31-33	3	1
α-helix	39-42	4
α-helix	54-56	3
β-strand	59-64	6	2
β-strand	68-73	6	2
β-strand	78-80	3	2
α-helix	84-116	33

Chain B: 4 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	6-9	4
β-strand	12-16	5	3
β-strand	22-26	5	3
β-strand	31-33	3	3
α-helix	39-42	4
α-helix	54-56	3
β-strand	59-64	6	4
β-strand	68-73	6	4
β-strand	78-80	3	4
α-helix	84-128	45

Chain C: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	280-286	7

Chain D: 2 helices, 0 β-strands

Element	Residues	Length	Sheet
α-helix	279-281	3
α-helix	283-286	4

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Protein KIBRA	A, B	protein	134	Mus musculus	Q5SXA9 (AlphaFold model)
Peptide from Angiomotin	C, D	protein	26	Homo sapiens	Q4VCS5 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>6JJX_1 Protein KIBRA (chains A, B)
GPGSEFELPLPEGWEEARDFDGKVYYIDHRNRTTSWIDPRDRYTKPLTFADCISDELPLG
WEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQ
QRLELAQQEYQQLH

Sequence of entity 2 (C, D), FASTA

>6JJX_2 Peptide from Angiomotin (chains C, D)
GPGSGRTEGQLMRYQHPPEYGAARPA

Primary citation

Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Lin, Z., Yang, Z., Xie, R. et al. Elife (2019) 8. DOI 10.7554/eLife.49439 · PubMed

Other PDB entries of the same protein (UniProt Q5SXA9 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6JJY 2.3 Å, Crystal Structure of KIBRA and beta-Dystroglycan
6JJW 2.4 Å, Crystal Structure of KIBRA and PTPN14 complex
6J68 2.5 Å, Structure of KIBRA and LATS1 Complex
6J69 2.75 Å, Structure of KIBRA and Dendrin Complex

Browse structure collections

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