6LTH: Human BAF Base module
Structure of human BAF Base module. Determined by electron microscopy at 3.0 Å resolution. Released 12 Feb 2020.
- Method
- Electron microscopy
- Resolution
- 3.0 Å
- Organism
- Homo sapiens
- Chains
- 8
- Atoms
- 14,970
- Mol. weight
- 886.78 kDa
- Ligands
- ZN
- Released
- 12 Feb 2020
Explore 6LTH in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6LTH contains 89 α-helices and 33 β-strands across 8 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain I: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 356-357 | 2 | |
| α-helix | 363-386 | 24 | |
| α-helix | 397-408 | 12 | |
| α-helix | 410-427 | 18 | |
| α-helix | 431-433 | 3 | |
| α-helix | 447-474 | 28 | |
Chain L: 27 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 1646-1648 | 3 | |
| α-helix | 1649-1651 | 3 | |
| α-helix | 1657-1659 | 3 | |
| α-helix | 1669-1678 | 10 | |
| α-helix | 1681-1696 | 16 | |
| α-helix | 1698-1700 | 3 | |
| α-helix | 1706-1708 | 3 | |
| α-helix | 1712-1728 | 17 | |
| β-strand | 1735 | 1 | 1 |
| α-helix | 1741-1744 | 4 | |
| β-strand | 1814-1816 | 3 | 2 |
| α-helix | 1841-1845 | 5 | |
| β-strand | 1849 | 1 | 1 |
| β-strand | 1955 | 1 | 3 |
| α-helix | 1972-1991 | 20 | |
| α-helix | 1997-2001 | 5 | |
| α-helix | 2005-2015 | 11 | |
| α-helix | 2021-2022 | 2 | |
| β-strand | 2023 | 1 | 3 |
| α-helix | 2050-2067 | 18 | |
| α-helix | 2068-2070 | 3 | |
| α-helix | 2078-2093 | 16 | |
| α-helix | 2114-2126 | 13 | |
| α-helix | 2129-2136 | 8 | |
| α-helix | 2141-2157 | 17 | |
| α-helix | 2161-2177 | 17 | |
| α-helix | 2179-2186 | 8 | |
| α-helix | 2191-2208 | 18 | |
| α-helix | 2229-2242 | 14 | |
| α-helix | 2248-2251 | 4 | |
| α-helix | 2255-2263 | 9 | |
| α-helix | 2269-2283 | 15 | |
Chain M: 12 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-16 | 4 | |
| β-strand | 17 | 1 | 4 |
| β-strand | 26-28 | 3 | 4 |
| α-helix | 29-35 | 7 | |
| α-helix | 42-46 | 5 | |
| β-strand | 52-54 | 3 | 4 |
| α-helix | 57-65 | 9 | |
| α-helix | 81-83 | 3 | |
| β-strand | 89-92 | 4 | 4 |
| α-helix | 93-97 | 5 | |
| α-helix | 173-180 | 8 | |
| β-strand | 186-195 | 10 | 5 |
| β-strand | 198-207 | 10 | 5 |
| α-helix | 215-225 | 11 | |
| α-helix | 230-247 | 18 | |
| β-strand | 261-270 | 10 | 6 |
| β-strand | 273-282 | 10 | 6 |
| α-helix | 290-301 | 12 | |
| α-helix | 306-323 | 18 | |
| β-strand | 340 | 1 | 7 |
| α-helix | 343-347 | 5 | |
| β-strand | 352-355 | 4 | 6 |
Chain N: 12 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 424-426 | 3 | 8 |
| α-helix | 428-430 | 3 | |
| β-strand | 437-439 | 3 | 9 |
| α-helix | 440-445 | 6 | |
| α-helix | 448-451 | 4 | |
| α-helix | 459-474 | 16 | |
| α-helix | 483-489 | 7 | |
| α-helix | 494-506 | 13 | |
| α-helix | 603-615 | 13 | |
| α-helix | 621-627 | 7 | |
| α-helix | 632-640 | 9 | |
| α-helix | 672-681 | 10 | |
| α-helix | 686-701 | 16 | |
| α-helix | 859-948 | 90 | |
Chain O: 15 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 424-426 | 3 | 2 |
| α-helix | 440-445 | 6 | |
| α-helix | 447-449 | 3 | |
| α-helix | 459-474 | 16 | |
| α-helix | 483-489 | 7 | |
| β-strand | 490 | 1 | 7 |
| α-helix | 494-506 | 13 | |
| β-strand | 523-524 | 2 | 10 |
| α-helix | 525-527 | 3 | |
| β-strand | 533-535 | 3 | 8 |
| α-helix | 603-615 | 13 | |
| α-helix | 620-627 | 8 | |
| α-helix | 632-640 | 9 | |
| α-helix | 646-649 | 4 | |
| α-helix | 658-660 | 3 | |
| α-helix | 672-683 | 12 | |
| α-helix | 686-704 | 19 | |
| α-helix | 712-715 | 4 | |
| α-helix | 869-951 | 83 | |
Chain P: 13 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 129-131 | 3 | |
| α-helix | 135-140 | 6 | |
| α-helix | 144-172 | 29 | |
| β-strand | 294-297 | 4 | 11 |
| α-helix | 299-305 | 7 | |
| β-strand | 309-311 | 3 | 11 |
| α-helix | 312-326 | 15 | |
| β-strand | 329 | 1 | 12 |
| β-strand | 336 | 1 | 13 |
| β-strand | 337 | 1 | 12 |
| β-strand | 353 | 1 | 13 |
| α-helix | 354-356 | 3 | |
| α-helix | 357-360 | 4 | |
| α-helix | 362-364 | 3 | |
| β-strand | 365-366 | 2 | 11 |
| α-helix | 401-410 | 10 | |
| α-helix | 415-446 | 32 | |
| α-helix | 448-467 | 20 | |
| α-helix | 479-483 | 5 | |
| α-helix | 487-504 | 18 | |
Chain Q: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 187-206 | 20 | |
| α-helix | 221-275 | 55 | |
Chain R: 2 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-37 | 24 | |
| β-strand | 41-42 | 2 | 14 |
| β-strand | 49-50 | 2 | 14 |
| β-strand | 51-52 | 2 | 10 |
| α-helix | 59-61 | 3 | |
| β-strand | 63-64 | 2 | 9 |
| β-strand | 70-73 | 4 | 9 |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Transcription activator BRG1 | I | protein | 1647 | Homo sapiens | P51532 (AlphaFold model) |
| AT-rich interactive domain-containing protein 1A | L | protein | 2285 | Homo sapiens | O14497 (AlphaFold model) |
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | M | protein | 385 | Homo sapiens | Q12824 (AlphaFold model) |
| SWI/SNF complex subunit SMARCC2 | N, O | protein | 1214 | Homo sapiens | Q8TAQ2 (AlphaFold model) |
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | P | protein | 515 | Homo sapiens | Q96GM5 |
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | Q | protein | 411 | Homo sapiens | Q969G3 |
| Zinc finger protein ubi-d4 | R | protein | 391 | Homo sapiens | Q92785 |
Sequence of entity 1 (I), FASTA
>6LTH_1 Transcription activator BRG1 (chains I)
MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
RAKPVVSDDDSEEEQEEDRSGSGSEED
Sequence of entity 2 (L), FASTA
>6LTH_2 AT-rich interactive domain-containing protein 1A (chains L)
MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG
PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP
PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG
LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG
SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT
SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA
PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ
PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ
QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST
TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP
QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG
VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP
GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ
IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ
MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA
MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG
MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER
KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL
NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS
MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ
KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY
SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS
PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP
AKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATAT
AATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQG
RNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP
VPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV
PASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGL
LAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPG
QRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASEN
SEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFE
SKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSS
TLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKR
CVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQG
VSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQ
DPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKN
PVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQN
PPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLF
LIGQS
Sequence of entity 3 (M), FASTA
>6LTH_3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (chains M)
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER
KKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL
REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA
SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA
IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE
LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE
MEKKIRDQDRNTRRMRRLANTAPAW
Sequence of entity 4 (N, O), FASTA
>6LTH_4 SWI/SNF complex subunit SMARCC2 (chains N, O)
MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
LVPLQPKTPQQTSASQQMLNFPDKGKEKPTDMQNFGLRTDMYTKKNVPSKSKAAASATRE
WTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLA
YQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVE
EAAKVTGKADPAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEPREGGG
AIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVE
SEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLE
IKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQ
PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA
GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLG
LPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMA
NPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT
APSPGTVTPVPPPQ
Sequence of entity 5 (P), FASTA
>6LTH_5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (chains P)
MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR
PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN
HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKR
KLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSL
VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR
LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR
LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL
DNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAE
FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT
Sequence of entity 6 (Q), FASTA
>6LTH_6 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (chains Q)
MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIP
KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE
AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPD
DYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRK
LEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQ
EEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEG
TSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE
Sequence of entity 7 (R), FASTA
>6LTH_7 Zinc finger protein ubi-d4 (chains R)
MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR
HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE
ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRR
GKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGED
KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGR
SGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPS
MSEPPEGSWSCHLCLDLLKEKASIYQNQNSS
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 1 |
Primary citation
Structure of nucleosome-bound human BAF complex. He, S., Wu, Z., Tian, Y. et al. Science (2020) 367:875-881. DOI 10.1126/science.aaz9761 · PubMed
Other PDB entries of the same protein (UniProt P51532 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7TAB 1.16 Å, G-925 bound to the SMARCA4 (BRG1) Bromodomain
- 2GRC 1.5 Å, 1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF…
- 6ZS2 1.57 Å, Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in…
- 7TD9 1.61 Å, G-059 bound to the SMARCA4 (BRG1) Bromodomain
- 6HR2 1.76 Å, Crystal structure of PROTAC 2 in complex with the bromodomain of human SMARCA4 and…
- 3UVD 1.85 Å, Crystal Structure of the bromodomain of human Transcription activator BRG1 (SMARCA4) in…
- 5DKD 2.0 Å, Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3…
- 5EA1 2.0 Å, Crystal Structure of SMARCA4 bromodomain in complex with MPD
- 9DTX 2.11 Å, Crystal structure of PRT3789 in complex with the bromodomain of human BRG1 (SMARCA4) and…
- 7VRB 2.39 Å, Structure of the Human BRG1/SS18 complex
- 9UXC 2.74 Å, The ADP-bound structure of BCL7B-containing ARP module of the human SWI/SNF complex
- 7VDT 2.8 Å, The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
Browse structure collections
About this viewer
MolViewer shows 6LTH directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.