6MZC: Human TFIID BC core
Human TFIID BC core. Determined by electron microscopy at 4.5 Å resolution. Released 28 Nov 2018.
- Method
- Electron microscopy
- Resolution
- 4.5 Å
- Organism
- Homo sapiens
- Chains
- 10
- Atoms
- 21,254
- Mol. weight
- 600.04 kDa
- Released
- 28 Nov 2018
Explore 6MZC in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6MZC contains 112 α-helices and 76 β-strands across 10 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain B: 32 helices, 30 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 27-36 | 10 | 1 |
| β-strand | 45-54 | 10 | 1 |
| β-strand | 62-65 | 4 | 2 |
| β-strand | 66 | 1 | 3 |
| β-strand | 70-76 | 7 | 1 |
| α-helix | 103-117 | 15 | |
| β-strand | 126-129 | 4 | 2 |
| α-helix | 130-131 | 2 | |
| α-helix | 132-140 | 9 | |
| β-strand | 144-152 | 9 | 1 |
| β-strand | 160-162 | 3 | 4 |
| β-strand | 176-178 | 3 | 4 |
| α-helix | 186-189 | 4 | |
| β-strand | 192 | 1 | 3 |
| β-strand | 200-208 | 9 | 1 |
| β-strand | 214-215 | 2 | 4 |
| β-strand | 219-222 | 4 | 1 |
| β-strand | 232-242 | 11 | 1 |
| β-strand | 250-251 | 2 | 4 |
| β-strand | 254-257 | 4 | 5 |
| β-strand | 265-269 | 5 | 5 |
| α-helix | 274-280 | 7 | |
| α-helix | 284-295 | 12 | |
| β-strand | 304-309 | 6 | 5 |
| β-strand | 318-319 | 2 | 5 |
| β-strand | 322-326 | 5 | 5 |
| α-helix | 338-357 | 20 | |
| α-helix | 364-366 | 3 | |
| α-helix | 369-383 | 15 | |
| α-helix | 388-408 | 21 | |
| α-helix | 443-463 | 21 | |
| α-helix | 466-483 | 18 | |
| α-helix | 494-496 | 3 | |
| α-helix | 500-510 | 11 | |
| α-helix | 515-518 | 4 | |
| α-helix | 519-523 | 5 | |
| β-strand | 529-531 | 3 | 6 |
| β-strand | 534 | 1 | 7 |
| β-strand | 547-550 | 4 | 7 |
| β-strand | 565-570 | 6 | 8 |
| β-strand | 575-579 | 5 | 8 |
| β-strand | 586-589 | 4 | 7 |
| β-strand | 625-627 | 3 | 8 |
| β-strand | 638-640 | 3 | 6 |
| α-helix | 646-652 | 7 | |
| α-helix | 659-671 | 13 | |
| α-helix | 676-686 | 11 | |
| α-helix | 693-707 | 15 | |
| α-helix | 720-725 | 6 | |
| α-helix | 744-758 | 15 | |
| β-strand | 762 | 1 | 9 |
| β-strand | 766 | 1 | 9 |
| α-helix | 769-780 | 12 | |
| α-helix | 793-803 | 11 | |
| α-helix | 825-842 | 18 | |
| α-helix | 849-862 | 14 | |
| α-helix | 872-875 | 4 | |
| α-helix | 884-900 | 17 | |
| α-helix | 904-915 | 12 | |
| α-helix | 920-932 | 13 | |
| α-helix | 949-958 | 10 | |
| α-helix | 965-977 | 13 | |
Chain E: 3 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 873 | 1 | 10 |
| α-helix | 875-888 | 14 | |
| β-strand | 893 | 1 | 11 |
| α-helix | 896-924 | 29 | |
| α-helix | 941-970 | 30 | |
Chain G: 13 helices, 31 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 211-226 | 16 | |
| α-helix | 230-236 | 7 | |
| α-helix | 237-239 | 3 | |
| α-helix | 240-254 | 15 | |
| α-helix | 257-267 | 11 | |
| α-helix | 276-283 | 8 | |
| α-helix | 288-293 | 6 | |
| α-helix | 296-299 | 4 | |
| β-strand | 307 | 1 | 12 |
| α-helix | 311-321 | 11 | |
| α-helix | 328-336 | 9 | |
| β-strand | 339 | 1 | 12 |
| β-strand | 460 | 1 | 13 |
| β-strand | 462 | 1 | 14 |
| β-strand | 474-477 | 4 | 15 |
| β-strand | 482-486 | 5 | 15 |
| β-strand | 492-496 | 5 | 15 |
| α-helix | 506-509 | 4 | |
| α-helix | 511-519 | 9 | |
| α-helix | 526-528 | 3 | |
| β-strand | 537-539 | 3 | 15 |
| β-strand | 548-551 | 4 | 16 |
| β-strand | 558-561 | 4 | 16 |
| β-strand | 567-570 | 4 | 16 |
| β-strand | 577-581 | 5 | 16 |
| β-strand | 590-593 | 4 | 17 |
| β-strand | 600-603 | 4 | 17 |
| β-strand | 609-612 | 4 | 17 |
| β-strand | 622 | 1 | 17 |
| β-strand | 630-635 | 6 | 18 |
| β-strand | 642-646 | 5 | 18 |
| β-strand | 651-654 | 4 | 18 |
| β-strand | 661-665 | 5 | 18 |
| β-strand | 672-677 | 6 | 19 |
| β-strand | 683-688 | 6 | 19 |
| β-strand | 692-697 | 6 | 19 |
| β-strand | 703-707 | 5 | 19 |
| β-strand | 714-719 | 6 | 20 |
| β-strand | 725-730 | 6 | 20 |
| β-strand | 734-739 | 6 | 20 |
| β-strand | 758-760 | 3 | 20 |
| β-strand | 766-769 | 4 | 14 |
| β-strand | 778-782 | 5 | 14 |
| β-strand | 790-792 | 3 | 14 |
Chain H: 15 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 219-232 | 14 | |
| α-helix | 236-247 | 12 | |
| α-helix | 256-273 | 18 | |
| α-helix | 276-290 | 15 | |
| α-helix | 298-300 | 3 | |
| α-helix | 301-310 | 10 | |
| α-helix | 323-344 | 22 | |
| α-helix | 351-364 | 14 | |
| α-helix | 370-383 | 14 | |
| α-helix | 385-387 | 3 | |
| α-helix | 388-392 | 5 | |
| α-helix | 396-406 | 11 | |
| α-helix | 414-438 | 25 | |
| α-helix | 444-450 | 7 | |
| α-helix | 458-471 | 14 | |
Chain I: 19 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 16-25 | 10 | |
| α-helix | 33-58 | 26 | |
| β-strand | 65-66 | 2 | 21 |
| α-helix | 68-74 | 7 | |
| β-strand | 208 | 1 | 22 |
| α-helix | 209-211 | 3 | |
| α-helix | 218-232 | 15 | |
| α-helix | 236-247 | 12 | |
| α-helix | 258-273 | 16 | |
| α-helix | 276-290 | 15 | |
| α-helix | 298-303 | 6 | |
| α-helix | 305-313 | 9 | |
| α-helix | 320-322 | 3 | |
| α-helix | 324-341 | 18 | |
| α-helix | 350-354 | 5 | |
| α-helix | 355-364 | 10 | |
| α-helix | 370-382 | 13 | |
| α-helix | 385-406 | 22 | |
| α-helix | 414-438 | 25 | |
| α-helix | 444-449 | 6 | |
| α-helix | 458-472 | 15 | |
Chain K: 7 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 31-48 | 18 | |
| β-strand | 52 | 1 | 23 |
| α-helix | 55-79 | 25 | |
| α-helix | 90-99 | 10 | |
| α-helix | 106-117 | 12 | |
| α-helix | 119-122 | 4 | |
| α-helix | 172-197 | 26 | |
| β-strand | 200 | 1 | 24 |
| β-strand | 214 | 1 | 24 |
| α-helix | 223-226 | 4 | |
Chain M: 4 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-25 | 12 | |
| β-strand | 30-31 | 2 | 21 |
| α-helix | 33-60 | 28 | |
| α-helix | 68-81 | 14 | |
| α-helix | 88-100 | 13 | |
Chain O: 5 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 115-121 | 7 | |
| α-helix | 122-124 | 3 | |
| α-helix | 132-141 | 10 | |
| α-helix | 149-174 | 26 | |
| β-strand | 194 | 1 | 23 |
| α-helix | 197-203 | 7 | |
2 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Transcription initiation factor TFIID subunit 2 | B | protein | 1199 | Homo sapiens | Q6P1X5 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 4 | E | protein | 1085 | Homo sapiens | O00268 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 5 | G | protein | 800 | Homo sapiens | Q15542 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 6 | H | protein | 677 | Homo sapiens | P49848 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 6 | I | protein | 677 | Homo sapiens | P49848 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 8 | K | protein | 310 | Homo sapiens | Q7Z7C8 |
| Transcription initiation factor TFIID subunit 9 | M | protein | 264 | Homo sapiens | Q16594 |
| Transcription initiation factor TFIID subunit 10 | O | protein | 218 | Homo sapiens | Q12962 |
| Transcription initiation factor TFIID subunit 12 | R | protein | 161 | Homo sapiens | Q16514 |
| poly(UNK) | Z | protein | 238 | Homo sapiens | |
Sequence of entity 1 (B), FASTA
>6MZC_1 Transcription initiation factor TFIID subunit 2 (chains B)
MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANL
NRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPD
AGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLHFVVPSVEGSMAERGAHVFSC
GYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTI
PTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYP
YSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFIS
RMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLHPIFGG
GKEKDNPASHLHFSIKHPHTLSWEYYSMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLA
STASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRK
RNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNK
KKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVV
AQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMK
SLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIK
YNDNRKNKFSDNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNME
KLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIRIAALEAVVDYTKV
DRSYEELQWLLNMIQNDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSG
TSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVAGNQEA
ANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPAS
SRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTA
SKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSLSD
Sequence of entity 2 (E), FASTA
>6MZC_2 Transcription initiation factor TFIID subunit 4 (chains E)
MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGN
HVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA
PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP
GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT
PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP
AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT
LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT
SGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQA
HAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATL
QRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFL
STLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRS
LPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPP
VLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP
QQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASM
AGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVS
YVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDE
QEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKV
DCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENERETSHSLLLY
KAFLK
Sequence of entity 3 (G), FASTA
>6MZC_3 Transcription initiation factor TFIID subunit 5 (chains G)
MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD
GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA
GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG
PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF
YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF
RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA
GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN
APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD
DSSLIAGGFADSTVRVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKILY
GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF
VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN
CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS
RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV
VHLHFTRRNLVLAAGAYSPQ
Sequence of entity 4 (H), FASTA
>6MZC_4 Transcription initiation factor TFIID subunit 6 (chains H)
MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHM
GKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINT
PLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKG
KGQGATTADGKGKEKKAPPLLEGAPLRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRA
EALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKY
VHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFT
KSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGA
DHVQSLLLKHCAPVLAKLRPPPDNQDAYRAEFGSLGPLLCSQVVKARAQAALQAQQVNRT
TLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIV
MSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPSGP
GSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEAGDSPPPAPGT
PKANGSQPNSGSPQPAP
Sequence of entity 5 (I), FASTA
>6MZC_5 Transcription initiation factor TFIID subunit 6 (chains I)
MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHM
GKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINT
PLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKG
KGQGATTADGKGKEKKAPPLLEGAPLXXXXXXXXXXSVEQQLYYKEITEACVGSCEAKRA
EALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKY
VHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFT
KSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGA
DHVQSLLLKHCAPVLAKLRPPPDNQDAYRAEFGSLGPLLCSQVVKARAQAALQAQQVNRT
TLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIV
MSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPSGP
GSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEAGDSPPPAPGT
PKANGSQPNSGSPQPAP
Sequence of entity 6 (K), FASTA
>6MZC_6 Transcription initiation factor TFIID subunit 8 (chains K)
MADAAATAGAGGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVET
LTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVIT
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYQVLREKAA
SQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEMQQMEET
DSSEQDEQTDTENLALHISMEDSGAEKENTSVLQQNPSLSGSRNGEENIIDNPYLRPVKK
PKIRRKKSLS
Sequence of entity 7 (M), FASTA
>6MZC_7 Transcription initiation factor TFIID subunit 9 (chains M)
MESGKTASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH
AKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPXXXXXXXPDRY
CLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPM
SLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANES
SNALKRKREDDDDDDDDDDDYDNL
Sequence of entity 8 (O), FASTA
>6MZC_8 Transcription initiation factor TFIID subunit 10 (chains O)
MSCSGSGADPEAAPASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGG
TGPLAARAGEPAERRGAAPVSAGGAAPPEGAISNGVYVLPSAANGDVKPVVSSTPLVDFL
MQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGTA
SGSSRSKSKDRKYTLTMEDLTPALSEYGINVKKPHYFT
Sequence of entity 9 (R), FASTA
>6MZC_9 Transcription initiation factor TFIID subunit 12 (chains R)
MNQFGPSALINLSNFSSIKPEPASTPPQGSMANSTAVVKIPGTPGAGGRLSPENNQVLTK
KKLQDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHL
ERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK
Sequence of entity 10 (Z), FASTA
>6MZC_10 poly(UNK) (chains Z)
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
Primary citation
Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Patel, A.B., Louder, R.K., Greber, B.J. et al. Science (2018) 362. DOI 10.1126/science.aau8872 · PubMed
Other PDB entries of the same protein (UniProt Q6P1X5 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7EGH 3.04 Å, TFIID lobe C subcomplex
- 7EGB 3.3 Å, TFIID-based holo PIC on SCP promoter
- 7EG9 3.7 Å, TFIID-based intermediate PIC on SCP promoter
- 7EGC 3.9 Å, p53-bound TFIID-based holo PIC on HDM2 promoter
- 7ENA 4.07 Å, TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
- 7EGA 4.1 Å, TFIID-based intermediate PIC on PUMA promoter
- 7ENC 4.13 Å, TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
- 8GXS 4.16 Å, PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
- 7EDX 4.5 Å, p53-bound TFIID-based core PIC on HDM2 promoter
- 8GXQ 5.04 Å, PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
- 8WAK 5.47 Å, Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol…
- 8WAP 5.85 Å, Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol…
Browse structure collections
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