6TBM: SAGA
Structure of SAGA bound to TBP, including Spt8 and DUB. Determined by electron microscopy at 20.0 Å resolution. Released 12 Feb 2020.
- Method
- Electron microscopy
- Resolution
- 20.0 Å
- Organisms
- Komagataella phaffii (strain GS115 / ATCC 20864), Komagataella phaffii GS115, Homo sapiens
- Chains
- 18
- Atoms
- 48,800
- Mol. weight
- 1280.34 kDa
- Released
- 12 Feb 2020
Explore 6TBM in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6TBM contains 316 α-helices and 154 β-strands across 18 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A: 10 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 160-168 | 9 | |
| α-helix | 173-178 | 6 | |
| α-helix | 194-199 | 6 | |
| α-helix | 223-229 | 7 | |
| α-helix | 240-242 | 3 | |
| α-helix | 243-257 | 15 | |
| α-helix | 267-290 | 24 | |
| β-strand | 328 | 1 | 3 |
| α-helix | 332-341 | 10 | |
| α-helix | 347 | 1 | |
| α-helix | 351-355 | 5 | |
Chain B: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 399-413 | 15 | |
| α-helix | 463-470 | 8 | |
| α-helix | 510-521 | 12 | |
| α-helix | 531-537 | 7 | |
| α-helix | 547-556 | 10 | |
Chain C: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 40-43 | 4 | 4 |
| β-strand | 49-51 | 3 | 4 |
| α-helix | 52-54 | 3 | |
| α-helix | 55-59 | 5 | |
| α-helix | 238-243 | 6 | |
| α-helix | 259-276 | 18 | |
| β-strand | 293 | 1 | 5 |
| β-strand | 307 | 1 | 5 |
Chain D: 10 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 16-25 | 10 | |
| α-helix | 32-60 | 29 | |
| α-helix | 67-74 | 8 | |
| α-helix | 78-88 | 11 | |
| α-helix | 186-196 | 11 | |
| α-helix | 203-211 | 9 | |
| α-helix | 215-217 | 3 | |
| α-helix | 220-226 | 7 | |
| α-helix | 239-267 | 29 | |
| α-helix | 306-316 | 11 | |
Chain E: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 818-844 | 27 | |
| α-helix | 883-897 | 15 | |
| α-helix | 908-934 | 27 | |
| α-helix | 952-962 | 11 | |
| α-helix | 969-999 | 31 | |
Chain F: 8 helices, 9 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 70-74 | 5 | |
| β-strand | 83-84 | 2 | 6 |
| β-strand | 85-87 | 3 | 7 |
| β-strand | 92-94 | 3 | 7 |
| β-strand | 101 | 1 | 7 |
| α-helix | 108-116 | 9 | |
| β-strand | 119 | 1 | 8 |
| α-helix | 125-131 | 7 | |
| β-strand | 140-145 | 6 | 6 |
| β-strand | 185-190 | 6 | 6 |
| β-strand | 191 | 1 | 8 |
| α-helix | 195-202 | 8 | |
| α-helix | 214-229 | 16 | |
| α-helix | 248-250 | 3 | |
| β-strand | 266 | 1 | 9 |
| α-helix | 297-300 | 4 | |
| α-helix | 325-335 | 11 | |
Chain G: 13 helices, 28 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 44-56 | 13 | |
| α-helix | 62-68 | 7 | |
| α-helix | 106-119 | 14 | |
| α-helix | 126-129 | 4 | |
| α-helix | 134-147 | 14 | |
| α-helix | 150-160 | 11 | |
| α-helix | 171-176 | 6 | |
| α-helix | 181-186 | 6 | |
| α-helix | 189-195 | 7 | |
| α-helix | 205-211 | 7 | |
| α-helix | 223-232 | 10 | |
| α-helix | 353-366 | 14 | |
| α-helix | 378-380 | 3 | |
| β-strand | 381 | 1 | 11 |
| β-strand | 384-386 | 3 | 12 |
| β-strand | 393-398 | 6 | 13 |
| β-strand | 404-409 | 6 | 13 |
| β-strand | 414-418 | 5 | 13 |
| β-strand | 446-449 | 4 | 13 |
| β-strand | 456-461 | 6 | 14 |
| β-strand | 467-472 | 6 | 14 |
| β-strand | 477-481 | 5 | 14 |
| β-strand | 487-491 | 5 | 14 |
| β-strand | 498-503 | 6 | 15 |
| β-strand | 509-514 | 6 | 15 |
| β-strand | 519-523 | 5 | 15 |
| β-strand | 531-533 | 3 | 15 |
| β-strand | 540-545 | 6 | 16 |
| β-strand | 551-556 | 6 | 16 |
| β-strand | 560-565 | 6 | 16 |
| β-strand | 571-576 | 6 | 16 |
| β-strand | 584-587 | 4 | 17 |
| β-strand | 593-597 | 5 | 17 |
| β-strand | 604-607 | 4 | 17 |
| β-strand | 613-615 | 3 | 17 |
| β-strand | 625-630 | 6 | 18 |
| β-strand | 636-641 | 6 | 18 |
| β-strand | 645-650 | 6 | 18 |
| β-strand | 694-697 | 4 | 18 |
| β-strand | 703-706 | 4 | 12 |
| β-strand | 716-719 | 4 | 12 |
Chain H: 18 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-30 | 9 | |
| α-helix | 37-62 | 26 | |
| α-helix | 72-80 | 9 | |
| α-helix | 128-130 | 3 | |
| β-strand | 136-138 | 3 | 12 |
| β-strand | 141 | 1 | 11 |
| α-helix | 219-232 | 14 | |
| α-helix | 241-253 | 13 | |
| α-helix | 258-260 | 3 | |
| α-helix | 262-275 | 14 | |
| α-helix | 280-295 | 16 | |
| α-helix | 305-317 | 13 | |
| α-helix | 333-350 | 18 | |
| α-helix | 358-371 | 14 | |
| α-helix | 378-389 | 12 | |
| α-helix | 395-410 | 16 | |
| α-helix | 416-430 | 15 | |
| α-helix | 451-457 | 7 | |
| α-helix | 465-468 | 4 | |
| α-helix | 474-480 | 7 | |
10 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| TATA-box Binding Protein (TBP) | M | protein | 240 | Komagataella phaffii (strain GS115 / ATCC 20864) | P13393 (AlphaFold model) |
| Transcriptional coactivator HFI1/ADA1 | A | protein | 448 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QZA3 (AlphaFold model) |
| Subunit of SAGA histone acetyltransferase complex | C | protein | 698 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QZ39 |
| Spt20 | F | protein | 517 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QZ05 (AlphaFold model) |
| Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to act | D | protein | 341 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4R3E4 |
| Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex | E | protein | 1191 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4R5C7 |
| Transcription initiation factor TFIID subunit 10 | J | protein | 217 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QXP2 |
| Subunit (61/68 kDa) of TFIID and SAGA complexes | K | protein | 609 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4R150 |
| Subunit (90 kDa) of TFIID and SAGA complexes | G | protein | 722 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4R4L4 |
| Subunit (60 kDa) of TFIID and SAGA complexes | H | protein | 485 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QW33 |
| Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation | I | protein | 153 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QZS5 |
| Transcription-associated protein | L | protein | 3825 | Komagataella phaffii (strain GS115 / ATCC 20864) | C4QYV4 |
6 more molecules are not listed.
Sequence of entity 1 (M), FASTA
>6TBM_1 TATA-box Binding Protein (TBP) (chains M)
MADEERLKEFKEANKIVFDPNTRQVWENQNRDGTKPATTFQSEEDIKRAAPESEKDTSAT
SGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGK
MVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHG
TFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM
Sequence of entity 2 (A), FASTA
>6TBM_2 Transcriptional coactivator HFI1/ADA1 (chains A)
MASTELVASTPMPSRNGQGSHQKLNGGNVNSATNTPTVASTPVNQPRKLPSENFSGLGGA
IRIEIEPLVVDFQRRLGKNWGRYQIAVSLFLVGKLSRRELVDELDDILDRNTVKMHNQLL
LGNLANSLKESAGDRVGSGGFGGSMFNKRVKDSRKSSQYERLKRDILALPVRERRRIKAI
TRESGKKGMVNSVITQTRQALIPKVPVVTRPTNVPGNSVQWAQDVIHGFQALLASEIYEL
PEMDNLRTRMTGISREHGLIGPVDDSVIEIMLIGLEQHLKGIVEAAIDIVKYRRTKYTNN
SVVDTLQKEQTNTSDTSSSKVSRKRDRHTLTIEDMYDTLEQYPYLVEPGGTLLRLQSVML
HDEDELSDDEILKHILKPRTSDSTDRKPKQLQENGTADSLSKVTKSITNGANASGDAVPN
GKAEHIQNTMGTKEELNWFIYDILSNNE
Sequence of entity 3 (C), FASTA
>6TBM_3 Subunit of SAGA histone acetyltransferase complex (chains C)
MQNPERPVVWKELGQYLDTLQPIHQEKPSSLPDLPSPSYKDSLSNPLRYRICNNCDRPIL
QSCLSKHIKICNQIVKVEKLEEDDKPMNMVRKRKNQVLEESKESTPVTNTNSTNSSNAIN
STTSKKTKKVKLPKEKKPKKERVKSTAKPKGPVDVERQCGVPLPNGGYCARSLTCKTHSM
GAKRAVPGRSAPYDQLLVAYQRKNQAKFAANAAAAHAARDDLIHGSQIPIDEDDEAHQVL
DGVAKSYPLPLERKVIMPARSRSSFLRMREMFAGAILPRVPTNPFGNLYSRTAVIDVDRA
GDYYFSVRASPRMPNQQQNKTQKNPQPPRPQVQQQQQAQKSQQSPPQAQQQISQSAGQQT
SQTVQRLVQQQQRLQQQRQQTQIQQQQQHQQQQQQQQHQQQQQQQQQQQQQQTHMLQQQQ
QQQQQQQMLLLQQQQQQQAQQQQSPPITHQSPIPDNRPSNQLPQQYSQMTPQQLQLQQQL
QLQQKQKEQFRLQQQQHLRNLXMRXTPQQQQQFANLTPEKRAQFQRMQLVQLQQQIKNQA
IQNQMQQQQQQPSHVQSQAQTQFQQAQLKAQSRAQVLQAAQRQMQNSPTSPVTSMSSPLA
IPSNLANQGPNQTSQLPNEQLSNPLMGNQFQGQFNQYQPNYRENLEGGGGSMDEKTTGWR
GGHVVEGLAGELEQLRARLEHHPQGQREPGGSHHHHHH
Sequence of entity 4 (F), FASTA
>6TBM_4 Spt20 (chains F)
MSQIQSSQVGAKNMQTAQPQAQQRPINGSVTLSNGQRINPQNLTPQQQRLLQQKVLHQKL
KNYKFAETSEEILHKYEKFPPSLTFHIHENHYRFGDQDGVIPKNSSVIKAFLEYVAREEI
PPALIEVTKDAGVQLYEGCIILRIYDHRHLVAHINDAKDSQHVSSESSANNTNNEKKEPS
KVPKTYTTILRPTQLSLYADLLYQTDYLQVRFTDSLSLNIETEILTASKRNLDLSVPLNP
HRATANLKPEVKYPYYDPETDTVVHEHRPDARGNMVNADTVDYRKLHEDMAQHGSDYERL
MLLLSDRFDDDSQTQGSSVTSSQFMRLRFVEAWRKKEERLQESGGSSQRQRPLQPGQIPG
MLSSFSSNTGNMNTMLDNLTPQQKAAIQQRMIQQGRAQPQQQQPDQEQLQEQQQQQPQQA
MSQQRQQQLQQLYQRQQQHNQHHQQNQDELSSLDDKKIKKPPAKKQKKMTKKEMTTLHQN
VAGKTIPSAESTPPTTAANKKRGTYKKKNKYILIIND
Sequence of entity 5 (D), FASTA
>6TBM_5 Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to act (chains D)
MTDAKDKDHKYRYRMEIQQMMFVSGETNDPPVETTSLIEDIVRSQVVEIVLHSSQTALSR
GTKSIVPEDVIFLIRHDKAKVNRLRTYLSWKDVRKNAKDQQSGDLADIGGDDLLDNSTSQ
VAASGAPGAPGSSSSTSMDSKMLSKYKKSKIRLPWELQFVFTEQPLDTNEDDAEDEDERA
ATLASLKRLKTNDERTKNMTKEEYVHWSECRQASFTFRKAKRFREWCGLSHLAESRPSDD
VIDILGFLTFEMVCSITEEALIVKMLEEQNGDLASSTTTIQKLQESHRKRKHLFDGPDKD
VRPITSGHVLEAWRRLQKRNVEKKAIRNFQGGKLRSRVQLI
Sequence of entity 6 (E), FASTA
>6TBM_6 Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex (chains E)
MANERALQYFVTSDNQRLYDLAAKLFSLGFFNCYFTPQQFQLLSVILDNGKLRIEEDGFV
STVWDEFIKGRLVLQFSKGDYEKESTKHTVDNVKGTDDKTGIEVSKENGHSSDPPSADHD
ITESDNVGREETLDDQFSELYLKDGVSTSQFMCAKLRYLLFEQAIDYLYTNSSMNGDAEE
YSLLQNVDDMNEEKEETAKPATPQNVREIDNDYDDDEDEDEEDEEIKEASSKNPFKTEDN
EPLTNERQPTNNVFIRLCSDEKSLSKSLTLNLLTSMVTSKPEYPVEQLKGSEVIGTSHPL
LGTASAIESKLEKRNEARLIKNFSKIYHQFDKDERNFLKRRKLEISNKQFLDQDNNDPKD
RPSSNSTSDEESNSNNLEKTSQPSSVNKLMQLGGAANLSLKNLLSKVEENREKLNLSDLD
LRSLIMDVRKNRSKWASDDKIGQEELYEACEKVVLELRGYTEHSTAFLNRVSKREAPNYY
QIIKKPMDLNTVMKKLKSFQYKSKQEFVDDLMLIWKNCLTYNSDPSHFIRVHAVAMQKKT
LSLIPLIPDIVIRDRSELEKDEVENVVETPQSSSIGTPMTTRVAGGKGPKKGRTHREPPT
RPETPDGIAGEDSSQVSKAEQDSPAKALEVTENDSTKEKEKDLSDVPTQEQKNDKTEKDD
DYQEAVEDEEEDDDDNTNLEEDSTEDEDDLEVQTWNSLTSNVRYKICEKRRNLFKENKIQ
PNEEAIFRDTYQMENFMHYLGDDVRIVLNTPMSRYQYYDGNEDPYLIEYDISGGIPGLKY
SGVSPDEGDLEDNMLVDQLMKGESSIRESGFARKPTGMNKKFNEIIHLMQQIRRICFKIS
LIRQMQTQQFLHHTQMKPPDINEIQDIDIDQLSNLPNRDKLDSDVSYNSLKRSISKILMA
NGFESTAPFCSDVITQIAENYFGNLVKTLKNHIESKSINKVMGDAKFQKVSNKDILLLSL
LENGVESPDALYEYYNENIVKQISKLEGLKSRLSSFLAELLRPGLQDLNERQFNDNSDEF
LTGNFSSEIGDDFFGFRELGLEKEFGLLTSTVPLHLLHSRLNSSIFNSNHEVSQLKFDDI
QAEEKEQLYKREIPQHIKLIQPFLYNIAEKSKTIHYKQLKKLNELQKMPENDDDILLIED
EDLPLKQRNTRPRVPPTGKIPNVKKKAVNGAYFLDPAIFSSNNQVKVEGDT
Sequence of entity 7 (J), FASTA
>6TBM_7 Transcription initiation factor TFIID subunit 10 (chains J)
MSTEKLFEDLDEDSLMQDVEGGVEGSMTIEEEPEPNDEKEAPHISMPSLPEYTRKDKTLE
EILEMMEDEEFTPIIPDAVTDYYLAKNGFETSDIKIKRILALATQKFISDIAQDAYEYSR
IRSSSSVYTSANPQARARQLVAGQQQQQQQQPQQQQQQQPQTGASQPAPTVGGSGGGGGG
GGGTSTGTNNKVVLTMDDLRSALGEYGINVKRPNFYR
Sequence of entity 8 (K), FASTA
>6TBM_8 Subunit (61/68 kDa) of TFIID and SAGA complexes (chains K)
MNQPPNQPQDNDSQVSSSGMQGGNSMNYSSSAPVNGAGQGPQPQQNSQGQNGKKPVGMQQ
AQIQLLARRYQLEMQKAHQLGPQTPQGAEHLQTATKIKHVLLSYQQQRQRQQGQVQGQGL
SQPQGQNQAQGRVQQQTQGLSPDPGSHQGSPQFQQPHQVMMGSAQTAGTSIANPQAQSNI
SSQVSQMAAAKVNSASPPIPPKTVGTPTGTPVGTQPRGQVTIQQFQQVKSILEEFEKKLR
TIEAAKRDQNLPEETLQKLLRQEAILKQRYAQTKATAYQMSQHLQRQQQALRAASAESAE
VYVTGSASSPNMNVYNQQILTQQPQQQLQQQQLHQPQPQQPQPARQSPHLLIHQQQQQQQ
QQQQQQQQQQQHPVTHRPSNVSQTMPQPSQPLQSSTPSSAVGRNQSPGATPVTSVNAAAK
PSPGTSSTSTLINQHILKPAPPPTEIPARLQVKPPQPAAMKIPNRPTLLGGSAISQPSLT
TPVSIRPPPLEMEGDHVLQKRKLKELLRNVGADEGDGETVIDGDVEELLLDLADEFVTSV
TSFACRLAKHRKVDNIDMRDVQLHLERNWNIRVPGYASDEIRSVRKFQPTAGYNQKVQGV
AISKSVNKN
Sequence of entity 9 (G), FASTA
>6TBM_9 Subunit (90 kDa) of TFIID and SAGA complexes (chains G)
MKQEPGDSSDKSAPSGSITPQPKPPQQANVSNQQPQKPQQFSAADLNRIVLEYLNKKGYH
KTESMLRMESSHIPAPPTNIPTPQTTNISRPTAPGRAPEYSDDPATIKRGYSILKSWCES
SLDFYRPELEKFLYPVFVHCYLDLIARGYPSHAREFYDKFSKDHSVLHEYEISKLGGISL
KEHLQENDVAKIFRSHKFKVLIGRTTFNLLLYFLNENDAVGGGVVLRLINQYIEPVITTE
AIAVEREGELNLSEGIVELHTLNNTSIGGEQREISSVDAFNKKPVKLGKLQVDPEYSKEL
EAELKLKDEHEQAAQKKVSTTLLEEYRENFKVDPSDENNPSKDTLPLPLKSAQDLRNDIA
MIQDSRAKIKLSAAQASLPSVCMYTFHNTNNDLTCLKFNDDSTMVASGFQDSFIKLWSID
GSPLRSLLKNDPYNQQNNDGVAVKGSRRLVGHSGAVYGVDFSPDNRYLISCSEDKTVRLW
SLDTYTCLVSYKGHSSSVWDVKFSPMGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDV
DCVEFHPNSTYLFTGSSDKTARMWDIARGECVRVFMGHSGAINCLAVSPDGRWLASAGED
SVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVSTGADNSVRVWDVKKNTNSPSA
QPEPINDVTAQGIQKKTEDLRRRKEIVATNDHMSVYFTKKTPVYTVHFTRRNLCLAGGVF
GG
Sequence of entity 10 (H), FASTA
>6TBM_10 Subunit (60 kDa) of TFIID and SAGA complexes (chains H)
MSKNSQRSSIPTSHTLWSPSDTVKDAAESLGIFNLNEEAAKNLAMDIEYRIHEILDQASK
FMRHGKRRTLHTSDIDRALKVLNLEPLYGYDVSRPLVFKEALVGAGQNLYYVDDDEVDFE
KLINEPLPKVPRFSTFTAHWLAIEGVQPAIPQNPSPNDIKNILPINRGSMENMFSLINDE
VKEDTNEEFTSTGPSVSSNISNQKQGLEVKPLVKHVLSRELQLYFDKIVEVLLNQEETKE
AELLRNSALQSVRADPGLHQLVPYFIQFISETITKNLKNISLLSTMLELIYSLLMNESLF
LEPYVHAIIPCILTLLLAKKIGNVDDELQKQQQLALRELSASLLERVIEDFGSSYSTLKP
RITRTLLRAFVSVNNTTPGTQYGALLGLRGLGSEVIRIVVLGNVINWSSTFLEKLQQEDQ
VFLIDTLIETLRVLTKEGKLVKDMKTENGIDNERLKQRVGDLIADRIQACDDAQDIYWGI
FFGEV
Sequence of entity 11 (I), FASTA
>6TBM_11 Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation (chains I)
MTNEQAAIPRDVRLLHLIFATQNIYSYQDHVPLQLMDFAYRYTTGTLQDATIYSDHAHAS
GSHISNAGNAGTNAQLTTEDIRLAIAARTNYQFKPVPPKELLLELAAERNKKPLPAVIPT
WGIRLPPEKYCLTGKDWVLEDEEEAVSYKKRKT
Sequence of entity 12 (L), FASTA
>6TBM_12 Transcription-associated protein (chains L)
MLHVVQLDDFATRLKAAEDYQSKHSVLSEICDSLETFNAAQDYEYFLKSLIPLFIDVLKE
VPVSFVANSPENKLRNITLEILHRIPANDALQAYSNEIVDTLMDLLKVENELNGILCMKA
ITTLHKTFKASLQEKVHPFIDIVIEIYSNIPQVVEEQFNGNQIDSKENVDSTSRPNSPSF
SSQSDDSKQLAQAMFSFKTLAESPITMVSLYSSYKELAASSLGNFIPHVMKVLSLEVAKQ
AEARKAAEEKGIILVNVCKEITNRANYGEFIIGQVKAASFLAYLFIRRQAQTFLEPYQQA
IPDIIIRLLQDCPSELSAARKELLHATRHILSTDFRKMFIPKIDLLFDLRVLIGEGFTAY
ETLRPLAYSTVADFIHNVRDHLTPAQLWKSVSIYCKNLQDDSLALTVQIMSAKLLLNLIE
KIMRSESKTESRQLLMVIIDAYTKRFKMLNSRYNGIMKQHATYEKEKQEKQNQERLLTNK
LDGTTPSPSDDKKVELIDEDQDVKMEDPTPEISDQETIKGDNDASTEPQDSEQQLADFMS
LQEYLPIQVSVPPEIDLLKDSRYLFKTLMTFLKTIMIGLKNSNPPSSQNHFNAQNWNETA
RGFSNEDINILKSLFRECILALRFFSTSKTSLPASSMKQSFDITGPNLPITSTKEEKDLM
EIFATMFIHIDPASFNEIVREELPFMYKQMLDFASLLHIPQFFLASVITSSSFSGILITF
LKSKLVDLGEVNIIKSNILIRLFKLCFMSVSLFPAANESVILPHLNELILKSLKLSTTAK
EPLVYFYLIRTLFRSIGGGRFENLYKEIMPLLQVLLESLSKLIHEARRPQERDIYVELCL
TVPVRLSVLVPHLSYLMKPLVYALNGSQESVSQGLRTLELCVDNLTAEYFDPIIEPVIDD
VMEALSKHLKPLPYYHQHSHTTLRILGKLGGRNRTFIKPVDNLKTDSELFQNVEAMFKIH
GLPNEVPLSITPGLSAAFSLLTDPRPRIHYRINSFKYISGIFQLFLGATQLPDDYANRLK
ESMDIILEDTIAPDEPLNKLHHFPVKDIAKYDSQMELLVKLLESIFYAVSLQEVREESKA
LIRGTCNHFILLYFNKMVIDKRKFVRKFSVDNHEGNLFLNENCIFDAIIYALSSDNSAVR
SMGLESVQLIYDSCVELFGNIDCALKFAPLNVMCSKFIHCCFEEPYHKKLAGCIGLEMML
NSLDIPMKYFNARQLEIIRALFYVLRDTAPELPCEVTNTAKRLILNSLKEWNKELTRNDV
FSSVFQNLVSSLIVDLPNANEIVRATAQEALRTLSETTQVPIATMISPCKHILLAPIFGK
PLRALPFQMQIGNIDAITFCMGLENSFLEYNEELNRLVQEALALVDAEDESLVSAHRISE
HKTSEQLVRLRVVCIQLLSLAITKPEFAAAQQRSNIRVKILVVFFKSLCGRSIEIIRAAH
GGLKAVIDLKMKLPKELLQNGLRPMLMNLSDHKKLTVASLEALSGLLKLFISYFKVGIGS
KLLDHLLAWAQPRTLQQLGSQDLENNSTVQIIVAILDVFHLLPPTAHKFMNDLMNALLYL
ENNLHRCQYSPFREPLAKFLDRFPDESFEYFFNEFSKREITTRFVYFVGLDSCSSLRAKV
LESLPRVRGLLHQEGSAEEKCVRFSNLVDLCESLAASDKEWIKDKEELLGELLDAGSVCL
TLKRSSNVVSPLYFQVDQGFETLQLLYIEYFKSQPLGHEKVFNFIDKISKEGLPFVLEFD
DFIFNEVVKCQDIPTVQQTLDTIIRMTPQVSSLDARVYLYKRIFLPICIYESEMHGDLSR
LSQTENNELPAWLKSFDSDVWKATGPLVDDYTSTLEDRYRLELMQLTALLIKGAPTALTD
MRKDIIKFSWNYIKLDDNTSKQAAYVVTAYFISRFDTPSELTTRIFVALLRCHQIDTRYL
VKQALELLAPVLSERTNSELDWLKWPRRVLSEDGFNITQVANIYQLIVKFPDLFYPARDH
FIPNIITAMGKLTVMSNTSLENQQLAIDLAELILKWETKLPKSEKLGSAEETEKEKSVSE
DKMDIDVKEETKEDIAERPKAEDQIGGDDSDSSNILTSEDYEVSFAQREACVTFLIRYIC
ISTQRPSENELGKRALNILYELLGPKYWSEVTVKLQFFERFLMSSDLNQPSLLGYCLNAL
EVLAVALKWKPTTWIIENVSYLQKLLEKCLRSDNQDIQEILQKVLGIILEAINKETQGSE
EDEPEEVTNFISLIVNIIGEDLSNMTSVAAGVSLCWTLSLYRPNALDSLLPSIMRTFNKL
CRDHIAISLQGNQPQSGDFANIEFEAKVTTNLLEKILNLCAARISSLDDQRRVFLSLLAQ
LIDRSVDKDMLLKVINIVTEWIFKTDFYPTTKEKAGILGKMMIFDLRGEPELSKKFNQVI
VDIFESKELAHTELTARMETAFLFGTRLSDVSIRKKLMSILSDSLELDIDKRLFYIIKDQ
NWEYLSDYPWLNQALQLLYGSFHLDSPIRLSPEENTLSPLQSITEGLAREKSPVEKAPQN
IIDFVAKHNEFLDSVRSLTAGDILNPLIDISYQSAETIHNAWVVVFPVAYSAIESRYELE
FTRALVKLLFKDYHIRQQDARPNVIKSLLDGVGKCPGLHLPPHLVKYLGSNYNAWYGAIK
LLEELSEGQGIDNQKISDANQDALLEVYMSLQEDDMFYGTWRRRAKYFETNAALSYEQIG
IWDKALQLYEAAQIKARSGVFPFGESEYSLWEDHWIYCAEKLQHWEILTELAKHEGFTDL
LLECGWRGADWIADREPLEQSVKTVMDIPTPRRQIFQTFLALQGFSQQKDTLQDVSRLCD
EGIQLTLRKWNALPQRVTRAHIGLLHTFQQYVELMEASQVYSSLVTTNAQNLDVKSQELK
RVLQAWRERLPNVWDDINIWNDLVTWRQHVFGVINRVYMPFVPVLQQSNGTNNGNSYAYR
GYHEMAWVINRFAHVARKHEMPEVCINQLTKIYTLPNIEIQEAFLKLREQAKCHYQNSSE
LNTGLDVISNTNLVYFATQQKAEFFTLKGMFLAKLNAKDEANQAFATAVQIDLNLPKAWA
EWGFFNDRRFKENPEEIFHAKNAISCYLQAAGLYKDGKTRKLLCRILWLISLDDAAGSLA
KTFEDHHGESPVWYWITFVPQLLTSLSHKEAKIVRHILIQIAKSYPQSLHFQLRTTKEDY
QAIQRQAMAVNRAEEQSSNKQDTADSVLKNTNTPQPQTRTETSGTTAESDKKPSIPPKEE
QGSPQPSRPATTQASPQAQSQENGESSQKHPPEIPTTDSRQPWQDVEEIMGILKTAYPLL
ALSLESLVDQLNQRFKCNADEDAYRLVIVLYNDGVQQMNRVANPREEVKLPAATEASISR
FADSVLPKNIREVFEQDIIACNPNLETYISKLRKWRDCLEEKLDRSYGKADLERVSLHLS
LFHHQKFEDIEIPGQYLLHKDNNNHFIKIERFLPTLDLVRGSNGCYKRMTIRGNDGSLHP
FAVQFPAARHCRREERIFQLFRIFDDALSRKVQSRRRNISLTLPIAVPLSPHIRILNDDK
RYTTLMGIYEEFCRRKGQSRDEPFAYTIQKLRAAFDPRLPKPDIVSVRAEVLASIQSTLV
PSTLLKDYYTEKFSNYENYWLFRKQFTAQYASFIFMTYIMCINSRQPQKIHINEGSGNIW
TSEMLPTKVATGKTHSTAYNNSTLDPAVKAGAPIFYNTESVPFRLTPNIQKFIGEAGLEG
ILSVYILVIANSLSDSEFDMEQYLSLFVRDEVISWFAQQHRASAQTNQLREIVRVNVELL
TKRVLQLNHIPNSQNVATQFVLNLISQAVNPRNLAYTDSAWMAYL
Primary citation
Structure of SAGA and mechanism of TBP deposition on gene promoters. Papai, G., Frechard, A., Kolesnikova, O. et al. Nature (2020) 577:711-716. DOI 10.1038/s41586-020-1944-2 · PubMed
Other PDB entries of the same protein (UniProt P13393 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 1YTB 1.8 Å, Crystal structure of a yeast tbp/tata-box complex
- 1NH2 1.9 Å, Crystal structure of a yeast TFIIA/TBP/DNA complex
- 4B0A 1.97 Å, The high-resolution structure of yTBP-yTAF1 identifies conserved and competing…
- 6E16 2.4 Å, Ternary structure of c-Myc-TBP-TAF1
- 1RM1 2.5 Å, Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex
- 1YTF 2.5 Å, Yeast tfiia/tbp/dna complex
- 1TBP 2.6 Å, Crystal structure of yeast tata-binding protein and model for interaction with DNA
- 7Z0O 2.8 Å, Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA
- 7O4J 2.9 Å, Yeast RNA polymerase II transcription pre-initiation complex (consensus)
- 7OHA 2.9 Å, nucleosome with TBP and TFIIA bound at SHL +2
- 1NGM 2.95 Å, Crystal structure of a yeast Brf1-TBP-DNA ternary complex
- 7ML0 3.0 Å, RNA polymerase II pre-initiation complex (PIC1)
Browse structure collections
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