6TUT: RNA Polymerase III-Maf1 complex

Name: PDB 6TUT: Cryo-EM structure of the RNA Polymerase III-Maf1 complex
Published: 2020-02-19
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: transcription

Cryo-EM structure of the RNA Polymerase III-Maf1 complex. Determined by electron microscopy at 3.25 Å resolution. Released 19 Feb 2020.

Method: Electron microscopy
Resolution: 3.25 Å
Organism: Saccharomyces cerevisiae S288C
Chains: 18
Atoms: 40,324
Mol. weight: 725.06 kDa
Ligands: ZN
Released: 19 Feb 2020

Explore 6TUT in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6TUT contains 224 α-helices and 290 β-strands across 18 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 69 helices, 63 β-strands

Element	Residues	Length	Sheet
β-strand	3-4	2	1
β-strand	11-19	9	2
α-helix	23-28	6
β-strand	30-33	4	3
β-strand	40-41	2	4
β-strand	47-48	2	4
α-helix	49	1
β-strand	81-91	11	3
α-helix	96-103	8
β-strand	106	1	5
β-strand	113	1	5
α-helix	117-127	11
α-helix	134-143	10
β-strand	153	1	6
β-strand	160	1	6
β-strand	163-165	3	7
β-strand	179-181	3	7
α-helix	191-201	11
α-helix	209-214	6
β-strand	220-221	2	7
α-helix	224-231	8
α-helix	240-242	3
α-helix	253-256	4
β-strand	257-263	7	3
α-helix	264-265	2
α-helix	284-305	22
α-helix	309-327	19
α-helix	354-357	4
β-strand	370-373	4	8
β-strand	376-383	8	9
β-strand	391-395	5	9
β-strand	403-407	5	10
α-helix	413-422	10
β-strand	430-434	5	10
α-helix	441	1
β-strand	442-443	2	10
α-helix	449-454	6
β-strand	461-465	5	10
α-helix	466	1
β-strand	471-475	5	9
α-helix	482-484	3
β-strand	485-493	9	9
β-strand	498-500	3	9
β-strand	516-520	5	9
α-helix	525-533	9
β-strand	536	1	9
β-strand	542	1	11
β-strand	549	1	11
α-helix	556-565	10
β-strand	570-571	2	12
α-helix	573-582	10
α-helix	592-595	4
β-strand	597	1	13
β-strand	603	1	13
β-strand	604-605	2	12
α-helix	606-614	9
β-strand	625-629	5	14
α-helix	634-636	3
α-helix	647-649	3
β-strand	651-655	5	14
β-strand	659-661	3	14
α-helix	666-669	4
α-helix	677-685	9
α-helix	687-700	14
α-helix	705-708	4
α-helix	714-717	4
α-helix	718-720	3
α-helix	723-746	24
α-helix	758-770	13
α-helix	773-782	10
α-helix	786	1
α-helix	790-796	7
α-helix	803-810	8
β-strand	814-815	2	15
β-strand	818	1	16
β-strand	821	1	16
α-helix	842-845	4
β-strand	847-848	2	15
α-helix	858-872	15
α-helix	876-893	18
β-strand	897-898	2	17
β-strand	904-905	2	17
β-strand	911-913	3	17
α-helix	916-918	3
β-strand	921	1	18
α-helix	923-925	3
α-helix	935-945	11
α-helix	952-955	4
α-helix	956-966	11
β-strand	977	1	19
β-strand	983	1	19
α-helix	992-994	3
α-helix	999-1024	26
α-helix	1049-1053	5
α-helix	1055-1059	5
α-helix	1067-1080	14
β-strand	1082	1	18
α-helix	1083-1084	2
α-helix	1089-1098	10
α-helix	1123-1130	8
β-strand	1131	1	20
β-strand	1141-1142	2	21
β-strand	1144-1145	2	22
α-helix	1151-1161	11
β-strand	1164-1165	2	23
β-strand	1170-1177	8	24
β-strand	1182-1188	7	24
α-helix	1202-1212	11
α-helix	1219-1221	3
β-strand	1222-1225	4	24
β-strand	1229-1234	6	24
α-helix	1256-1265	10
β-strand	1271-1273	3	23
β-strand	1281-1282	2	21
β-strand	1285	1	25
β-strand	1291	1	25
β-strand	1294-1295	2	21
α-helix	1301-1305	5
β-strand	1309-1310	2	22
α-helix	1319-1326	8
α-helix	1329-1342	14
α-helix	1343-1345	3
α-helix	1353-1361	9
β-strand	1370	1	20
α-helix	1373-1379	7
α-helix	1384-1389	6
α-helix	1397-1401	5
β-strand	1405-1406	2	2
α-helix	1411-1417	7
α-helix	1424-1427	4
β-strand	1429-1432	4	1
α-helix	1448-1455	8

Chain B: 50 helices, 89 β-strands

Element	Residues	Length	Sheet
α-helix	41-46	6
α-helix	47-54	8
α-helix	59-67	9
α-helix	68-72	5
α-helix	74-77	4
β-strand	82-83	2	26
β-strand	93-100	8	26
α-helix	109-111	3
α-helix	115-120	6
β-strand	127-137	11	26
β-strand	140-152	13	26
α-helix	154	1
β-strand	155	1	27
α-helix	170-173	4
β-strand	185-187	3	27
β-strand	190-194	5	27
β-strand	196-200	5	28
β-strand	206-207	2	29
β-strand	217-218	2	29
β-strand	219-223	5	30
β-strand	227-231	5	30
β-strand	235-236	2	31
β-strand	239-240	2	31
β-strand	241-242	2	32
β-strand	244	1	30
β-strand	247	1	33
α-helix	250	1
β-strand	251-252	2	32
α-helix	254-257	4
α-helix	268-271	4
α-helix	277-292	16
α-helix	298-306	9
β-strand	309	1	33
α-helix	319-329	11
α-helix	343-361	19
α-helix	372-374	3
β-strand	375-378	4	28
α-helix	380-407	28
α-helix	422-439	18
β-strand	442-444	3	34
β-strand	449-451	3	34
β-strand	455-457	3	27
α-helix	458-459	2
α-helix	463-468	6
β-strand	472-474	3	28
α-helix	489-490	2
α-helix	491-493	3
β-strand	497	1	35
β-strand	508	1	36
β-strand	511	1	36
β-strand	512-513	2	28
β-strand	514	1	35
β-strand	519-520	2	37
α-helix	521-523	3
α-helix	527-535	9
β-strand	540	1	38
α-helix	548-551	4
β-strand	553	1	39
β-strand	554-557	4	40
β-strand	560-561	2	40
β-strand	563	1	38
β-strand	565	1	39
α-helix	568-580	13
β-strand	589-592	4	40
β-strand	598-602	5	40
β-strand	608-609	2	37
β-strand	610-614	5	41
β-strand	615-616	2	42
β-strand	619-620	2	42
α-helix	624-631	8
α-helix	639-642	4
β-strand	646-649	4	41
β-strand	659-660	2	41
α-helix	663-665	3
β-strand	672-673	2	41
α-helix	677-680	4
α-helix	691-693	3
α-helix	696-706	11
β-strand	709	1	43
β-strand	711	1	44
β-strand	725-728	4	44
β-strand	732	1	45
β-strand	736-737	2	46
α-helix	739-743	5
α-helix	746-748	3
β-strand	753-759	7	47
β-strand	770-774	5	47
α-helix	775-780	6
β-strand	785-795	11	44
β-strand	797	1	48
β-strand	803	1	48
β-strand	805-806	2	49
β-strand	811-812	2	50
β-strand	814-817	4	50
α-helix	819-821	3
β-strand	829	1	51
α-helix	830-831	2
β-strand	832	1	52
α-helix	834	1
β-strand	835-836	2	44
β-strand	841-843	3	51
β-strand	845-847	3	49
β-strand	867-868	2	49
β-strand	871-872	2	51
β-strand	879-888	10	44
β-strand	894-904	11	44
β-strand	911-913	3	47
β-strand	919-926	8	47
β-strand	933	1	53
β-strand	942-944	3	47
α-helix	955-970	16
β-strand	974-975	2	46
α-helix	984-994	11
β-strand	1001-1002	2	47
α-helix	1004	1
β-strand	1005	1	53
α-helix	1006	1
β-strand	1012	1	53
α-helix	1013	1
β-strand	1017-1026	10	47
β-strand	1027	1	43
α-helix	1031-1033	3
β-strand	1036-1038	3	9
β-strand	1043	1	54
β-strand	1050	1	54
β-strand	1060-1063	4	8
α-helix	1067-1072	6
α-helix	1076-1080	5
α-helix	1081-1085	5
β-strand	1089-1095	7	55
α-helix	1100	1
β-strand	1101-1102	2	55
β-strand	1103	1	56
β-strand	1106	1	56
β-strand	1107	1	57
β-strand	1112	1	57
β-strand	1116-1122	7	55
α-helix	1123-1132	10
β-strand	1138-1145	8	2

Chain C: 9 helices, 18 β-strands

Element	Residues	Length	Sheet
β-strand	4-7	4	58
β-strand	12-13	2	58
α-helix	33-39	7
β-strand	41-47	7	58
β-strand	51-57	7	58
α-helix	61-73	13
β-strand	77-86	10	59
α-helix	94-101	8
α-helix	110-112	3
β-strand	133-139	7	59
β-strand	142	1	60
β-strand	157	1	60
β-strand	161-163	3	61
α-helix	164-166	3
β-strand	167-170	4	59
α-helix	175-178	4
β-strand	192-195	4	61
β-strand	201-211	11	59
α-helix	217-219	3
β-strand	222-226	5	58
β-strand	229-234	6	58
α-helix	242-249	8
β-strand	256-258	3	62
β-strand	265-267	3	62
β-strand	290-304	15	58
α-helix	310-329	20
β-strand	334	1	63

Chain D: 9 helices, 2 β-strands

Element	Residues	Length	Sheet
β-strand	2-5	4	1
β-strand	10-11	2	1
α-helix	13-26	14
α-helix	55-61	7
α-helix	63-66	4
α-helix	106-109	4
α-helix	111-113	3
α-helix	117-125	9
α-helix	131-137	7
α-helix	151-153	3
α-helix	154-158	5

Chain E: 12 helices, 12 β-strands

Element	Residues	Length	Sheet
α-helix	2-25	24
β-strand	28	1	64
α-helix	32-34	3
α-helix	41	1
α-helix	42-46	5
β-strand	61-62	2	65
β-strand	64	1	64
α-helix	66-71	6
β-strand	78-82	5	65
β-strand	87-88	2	66
α-helix	90-101	12
β-strand	107-112	6	65
β-strand	115-116	2	66
α-helix	118-121	4
β-strand	132-136	5	65
α-helix	138-140	3
α-helix	144-146	3
β-strand	152-155	4	67
α-helix	156-157	2
α-helix	158-167	10
β-strand	177-178	2	67
α-helix	185-188	4
β-strand	195-201	7	67
β-strand	207-214	8	67

Chain F: 4 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	84	1	68
α-helix	85-86	2
α-helix	87-102	16
α-helix	105-107	3
α-helix	117-126	10
β-strand	133-137	5	1
β-strand	143-147	5	1
β-strand	152	1	68

Chain G: 5 helices, 17 β-strands

Element	Residues	Length	Sheet
β-strand	2-13	12	1
α-helix	15-19	5
α-helix	22-34	13
β-strand	37-39	3	1
β-strand	43-45	3	1
β-strand	50-54	5	1
β-strand	57-58	2	1
β-strand	66-77	12	1
β-strand	84-91	8	69
β-strand	97	1	70
β-strand	98-100	3	69
β-strand	108-109	2	69
β-strand	110	1	70
α-helix	112-114	3
β-strand	120-122	3	71
β-strand	127-131	5	71
β-strand	137-140	4	71
β-strand	145-155	11	69
α-helix	163-173	11
α-helix	190-192	3
β-strand	194-199	6	69
β-strand	206-207	2	69

Chain H: 1 helix, 13 β-strands

Element	Residues	Length	Sheet
β-strand	4-14	11	13
β-strand	23-25	3	72
β-strand	27-30	4	13
β-strand	38	1	73
β-strand	41-43	3	72
β-strand	54-60	7	13
β-strand	64	1	74
α-helix	81-83	3
β-strand	88	1	74
β-strand	95-99	5	13
β-strand	100-108	9	73
β-strand	111-118	8	73
β-strand	121-127	7	73
β-strand	140-145	6	13

10 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase III subunit RPC1	A	protein	1460	Saccharomyces cerevisiae S288C	P04051 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC2	B	protein	1149	Saccharomyces cerevisiae S288C	P22276 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC1	C	protein	335	Saccharomyces cerevisiae S288C	P07703 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC9	D	protein	161	Saccharomyces cerevisiae S288C	P47076 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	215	Saccharomyces cerevisiae S288C	P20434
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	155	Saccharomyces cerevisiae S288C	P20435
DNA-directed RNA polymerase III subunit RPC8	G	protein	212	Saccharomyces cerevisiae S288C	P35718
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	146	Saccharomyces cerevisiae S288C	P20436
DNA-directed RNA polymerase III subunit RPC10	I	protein	110	Saccharomyces cerevisiae S288C	Q04307
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	70	Saccharomyces cerevisiae S288C	P22139
DNA-directed RNA polymerases I and III subunit RPAC2	K	protein	142	Saccharomyces cerevisiae S288C	P28000
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	70	Saccharomyces cerevisiae S288C	P40422

6 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>6TUT_1 DNA-directed RNA polymerase III subunit RPC1 (chains A)
MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGV
SSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDK
RQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIH
DTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVKRCMDDLNPLKTLNLFKQIKSADCE
LLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIK
AGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGK
QGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELI
VNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSL
HRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNN
LLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLSMMSDGIEHFDIPPPAIMKP
YYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQIL
SGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPA
DDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDV
CINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSK
TPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQY
DNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIM
ETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALA
NLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRK
ARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPI
INAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLEL
TIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRM
QQLRRALPDVVVKGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVL
EVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMR
DSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKD
LVPKRCLFESLSNEAALKAN

Sequence of entity 2 (B), FASTA

>6TUT_2 DNA-directed RNA polymerase III subunit RPC2 (chains B)
MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQ
HLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRL
RDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLD
PGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKI
YLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQ
ALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAM
YNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALL
SINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKS
RKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVED
ITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVH
IATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIA
LYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKR
IDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDR
GFGRCETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQ
IYINKSVPTNSADAPNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLL
RQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIE
LISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFG
PIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLL
ERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPR
LRLEDIFQQ

Sequence of entity 3 (C), FASTA

>6TUT_3 DNA-directed RNA polymerases I and III subunit RPAC1 (chains C)
MSNIVGIEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINID
TSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNL
PDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFA
DCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIK
GESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIF
NVESAGAMTPEEIFFKSVRILKNKAEYLKNCPITQ

Sequence of entity 4 (D), FASTA

>6TUT_4 DNA-directed RNA polymerase III subunit RPC9 (chains D)
MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITR
NVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEK
LQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA

Sequence of entity 5 (E), FASTA

>6TUT_5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>6TUT_6 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>6TUT_7 DNA-directed RNA polymerase III subunit RPC8 (chains G)
MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLK
PGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCY
YTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEG
KNEETPQNEKPPAYALLGSCQTDGMGLVSWWE

Sequence of entity 8 (H), FASTA

>6TUT_8 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>6TUT_9 DNA-directed RNA polymerase III subunit RPC10 (chains I)
MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRKKLPRKEVDDVLGGGWD
NVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVNCGHRWKEN

Sequence of entity 10 (J), FASTA

>6TUT_10 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>6TUT_11 DNA-directed RNA polymerases I and III subunit RPAC2 (chains K)
MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTS
ASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKG
LKDLMDLCDVVESKFTEKIKSM

Sequence of entity 12 (L), FASTA

>6TUT_12 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	7

Primary citation

Structural basis for RNA polymerase III transcription repression by Maf1. Vorlander, M.K., Baudin, F., Moir, R.D. et al. Nat Struct Mol Biol (2020) 27:229-232. DOI 10.1038/s41594-020-0383-y · PubMed

Other PDB entries of the same protein (UniProt P04051 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7Z0H 2.6 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
7Z1O 2.7 Å, Structure of yeast RNA Polymerase III PTC + NTPs
7Z31 2.76 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11,…
7Z1L 2.8 Å, Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
7Z30 2.9 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11…
7Z2Z 3.07 Å, Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
8BWS 3.2 Å, Structure of yeast RNA Polymerase III elongation complex at 3.3 A
6EU3 3.3 Å, Apo RNA Polymerase III - closed conformation (cPOL3)
6EU1 3.4 Å, RNA Polymerase III - open DNA complex (OC-POL3).
6EU2 3.4 Å, Apo RNA Polymerase III - open conformation (oPOL3)
7Z1M 3.4 Å, Structure of yeast RNA Polymerase III Elongation Complex (EC)
6F40 3.7 Å, RNA Polymerase III open complex

Browse structure collections

About this viewer

MolViewer shows 6TUT directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.