7LX6: T4 lysozyme mutant L99A

T4 lysozyme mutant L99A. Determined by X-ray diffraction at 1.05 Å resolution. Released 29 Sept 2021.

Method: X-ray diffraction
Resolution: 1.05 Å
Organism: Enterobacteria phage T4
Chains: 1
Atoms: 1,442
Mol. weight: 20.02 kDa
Ligands: YGG
Released: 29 Sept 2021

Explore 7LX6 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7LX6 contains 10 α-helices and 6 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 10 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	3-11	9
β-strand	14-15	2	1
β-strand	16	1	2
β-strand	17-19	3	1
β-strand	25-28	4	1
β-strand	31-34	4	1
α-helix	39-50	12
β-strand	57	1	2
α-helix	60-80	21
α-helix	84-90	7
α-helix	93-106	14
α-helix	111-114	4
α-helix	115-122	8
α-helix	126-134	9
α-helix	137-141	5
α-helix	143-155	13

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Lysozyme	A	protein	172	Enterobacteria phage T4	P00720

Sequence of entity 1 (A), FASTA

>7LX6_1 Lysozyme (chains A)
MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITK
DEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCAAINMVFQMGETGVAGFTNSLRM
LQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNLLEHHHHHH

Ligands and cofactors

ID	Name	Formula	Copies
YGG	5-[(2-phenylethyl)sulfanyl]-1H-1,2,3-triazole	C10 H11 N3 S	1

Water and common crystallization additives (TRS) are not listed.

Primary citation

Energy penalties enhance flexible receptor docking in a model cavity. Kamenik, A.S., Singh, I., Lak, P. et al. Proc Natl Acad Sci U S A (2021) 118. DOI 10.1073/pnas.2106195118 · PubMed

Other PDB entries of the same protein (UniProt P00720), best resolution first:

2O7A 0.84 Å, T4 lysozyme C-terminal fragment
5JDT 1.0 Å, Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K
7LOE 1.01 Å, T4 lysozyme mutant L99A in complex with 1-fluoranylnaphthalene
7LOD 1.02 Å, T4 lysozyme mutant L99A in complex with 1-fluoranyl-4-iodanyl-benzene
7LX8 1.03 Å, T4 lysozyme mutant L99A
5XPF 1.04 Å, High-resolution X-ray structure of the T26H mutant of T4 lysozyme
6BG3 1.05 Å, Structure of (3S,4S)-1-benzyl-4-(3-(3-(trifluoromethyl)phenyl)ureido)piperidin-3-yl…
7LOF 1.05 Å, T4 lysozyme mutant L99A in complex with 2-butylthiophene
7LX7 1.05 Å, T4 lysozyme mutant L99A
1SWY 1.06 Å, Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure…
1SWZ 1.06 Å, Use of an ion-binding site to bypass the 1000-atom limit to ab initio structure…
1SX2 1.06 Å, Use of a Halide Binding Site to Bypass the 1000-atom Limit to Structure Determination by…

Browse structure collections

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