Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia. Determined by electron microscopy at 3.4 Å resolution. Released 27 Oct 2021.
Explore 7RRO in 3D Show helices and sheets RCSB PDB PDBe
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Protein C9orf135 homolog | 0, 7 | protein | 232 | Bos taurus | Q32L77 (AlphaFold model) |
| EF-hand domain family member B | 1, 2 | protein | 877 | Bos taurus | F1MMV1 (AlphaFold model) |
| Methyl-CpG binding domain protein 1 | 3, 4 | protein | 514 | Bos taurus | F1N7G5 (AlphaFold model) |
| Nucleoside diphosphate kinase 7 | 5, 6 | protein | 377 | Bos taurus | Q5E9Y9 (AlphaFold model) |
| Uncharacterized protein C1orf158 homolog | 8, 9 | protein | 196 | Bos taurus | Q2TA11 |
| Meiosis-specific nuclear structural protein 1 | A, B | protein | 494 | Bos taurus | Q2KIQ2 |
| Tektin-1 | A0, A1, A2, A3, A4 | protein | 418 | Bos taurus | Q32KZ9 |
| Tubulin alpha-1D chain | AA, AC, AE, AG, AI, AK, AM, BA, BC, BE, BG, BI, BK, BM, CA, CC, CE, CG, CI, CK, CM, DA, DC, DE, DG, DI, DK, DM, EC, EE, EG, EI, EK, EM, FC, FE, FG, FI, FK, FM, GC, GE, GG, GI, GK, GM, HC, HE, HG, HI, HK, HM, HO, IC, IE, IG, II, IK, IM, IO, JC, JE, JG, JI, JK, JM, KC, KE, KG, KI, KK, KM, KO, LC, LE, LG, LI, LK, LM, MC, ME, MG, MI, MK, MM, NA, NC, NE, NG, NI, NK, OA, OC, OE, OG, OI, OK, PA, PC, PE, PG, PI, PK, PM, QA, QC, QE, QG, QI, QK, QM, RA, RC, RE, RG, RI, RK, RM, SA, SC, SE, SG, SI, SK, SM, TC, TE, TG, TI, TK, TM, UC, UE, UG, UI, UK, UM, VC, VE, VG, VI, VK, VM, WC, WE, WG, WI, WK, WM | protein | 452 | Bos taurus | Q2HJ86 |
| Tubulin beta-4B chain | AB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, DN, EB, ED, EF, EH, EJ, EL, EN, FB, FD, FF, FH, FJ, FL, FN, GB, GD, GF, GH, GJ, GL, GN, HB, HD, HF, HH, HJ, HL, HN, IB, ID, IF, IH, IJ, IL, IN, JB, JD, JF, JH, JJ, JL, JN, KB, KD, KF, KH, KJ, KL, KN, LB, LD, LF, LH, LJ, LL, LN, MB, MD, MF, MH, MJ, ML, MN, N0, NB, ND, NF, NH, NJ, NL, O0, OB, OD, OF, OH, OJ, OL, PB, PD, PF, PH, PJ, PL, QB, QD, QF, QH, QJ, QL, RB, RD, RF, RH, RJ, RL, SB, SD, SF, SH, SJ, SL, TB, TD, TF, TH, TJ, TL, UB, UD, UF, UH, UJ, UL, UN, VB, VD, VF, VH, VJ, VL, VN, WB, WD, WF, WH, WJ, WL, WN | protein | 445 | Bos taurus | Q3MHM5 |
| Tektin-2 | B0, B1, B2, B3, B4, B5, B6, B7, B8, B9 | protein | 430 | Bos taurus | Q2T9Q6 |
| Uncharacterized protein C1orf189 homolog | C | protein | 101 | Bos taurus | Q32L75 |
| Tektin-3 | C0, C1, C2, C3, C4, C5, C6, C7, C8, C9, F0, F1, F2, F3, F4 | protein | 490 | Bos taurus | A6H782 |
24 more molecules are not listed.
>7RRO_1 Protein C9orf135 homolog (chains 0, 7) MDSSDSSCQEWCSHGQYWLELGPTDLMERKGSLTLRSHHKKYSKPVLVYSWHRDRETYPK DYDIEGPEEVKKLCNSTYRRLGTSEPPVWISETREKMAQVCLNTKLAKIKSKALLNEETM NSGIIERDTGLPATGFGALFTRHSPDWSKMCTLTTYAEEYAPPYEYQPLGDPCQDDDYSI VHRKCRSQFTDLDGSKRVGINTWHDESGIYANSYVKRKLYSLTGGPIAPFLK
>7RRO_2 EF-hand domain family member B (chains 1, 2) MCSFLRVPSPKGLEPSKGLGAPLQPGTAYPSEMSALGPGMTVSGRKSPLSMEVGLAPEGK DDLEERRVFMGTTSPTELGLRVGLRKDFPCSKTYEERMASPEIRSPSSKGLELRLKRQNI SRTVMDGSNLGVHRVSASQETKPPLSALPGRVGLEKERFLAGYCPGRVTQPPLGQGCESP QASGGRRCPVTGDPEGFGASVSKLPALGMECRGELGGESACVVMKPRAETEPPVEVDMGL TRLEEPAEMESPEPQMGLVMEPPAWQLAQQPEEQREAENTEPGVEPPDRIRPIYSGKFFD RMPCWPSAGKVLPIGYRAATCLTERFPRLMTPPEAKKFFNFRYPPAGAERVFYGRANDPQ IAPSLTHGIRSKISIPAKVLINPQPITTFQQKMKDKKESVYFSNQRAPLGKSHDQTPGLP KGLDILNTTFGTAIVRETSARDMVNPPKPYKEVFEEAQAGHDLYVVSHNDYFVGEAKNRK YDPSSFHRFNLYGIPTPHFNDGRNMAKTLHWLHELQMKRGAKIVSKRVDDFKEKFQHRLG RVLDPIAETMNVPPDYTFGAFLRPEDYGVGDLIHRRLPGEYLRGKDRQRGLVAAVRHHLK KVNYQNFDTLLAAFRHYDKKGDGVIDRAELQEACDQACLHLDEKLLDQLFEYCDVDKDGL INYLEFANFLTWKDKTPLKEYEERVLIKGRKADCANPAEANVEESEPALLLKPEDIVLKE PGSSEKTLRTLLRPSDKVSNHYKTTSSEISAVVGAVPSTCYPTYGVPTIRSDIPAPLIRR VSDRTSYGEEGNAYSLLHPTIFAQKGVFERDFFKTRSKQEISEILCNIGVKLSEDEFENV WNLASKKHHRGEVCVENIRSVLDELQHADGAKCKAAT
>7RRO_3 Methyl-CpG binding domain protein 1 (chains 3, 4) MYSQRFGIVQREVKGPTPKVVIVRAKPPKGQGAEHHLQRIQHSHQKHHAILASIKSIERD RLKTEWDQHNDCKFVDSLVKARVKDAMQGFIINTEERRNKLRELLASEENEYFTEMQLKE ETIEEKKDRMRDKIRLLREKKEKERQDFVAEKLDQQFRERCQELRAELFCIHQKAVCEER KAQIAFNEELKRQKVVEEQMFSKLWEEDRLAKERREAKEERRQKELVENTRLGLNAQVTS IQAQRQAAQRLKEEEALLVENENAQVKLENEQDKLKKQKTKQEIRAALQKALQEKMERMQ QEYREEQDLNMKLMQNALQSLQEETDKKKQKKEDMRREQKIYYQYLAQRHEEEKAQEKEL DRMLEKEKEKKFAEKDKELRLEKEARKQLLNEVMCTRKLQVQEKLQRKAKEQEERTMEQE RINEGLKELNCEERENFIRRCSLAQEYRKQLQMQICSQQQAREAEEEEERREFEAGIAAE KSFQDKIQGILSTHQVVPRNIHPMRRACSTKLPP
>7RRO_4 Nucleoside diphosphate kinase 7 (chains 5, 6) MNHSERFVFIAEWFDPNASLFRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYEDLHLEDL FIGNKVNIFSRQLVLLDYGDQYTARQLGSKKEKTLALIKPDAVSKAGEIIEIINKAGFTL TKLKMMTLSRKEATDFHIDHQSRPFLNELIQFITSGPIIAMEILRDDAVCEWKRLLGPAN SGLARTDAPESIRALFGTDGIKNAAHGPDSFACAAREMELFFPSSGVCGPANTAKFTNCT TCCIVKPHAVSEGLLGKILMTIRDAGFEISAMQMFNMDRINVEEFYEVYKGVVSEYNEMV TEMYSGPCVAMEIQQTNPTMTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL PEDGLLEVQYFFKILDN
>7RRO_5 Uncharacterized protein C1orf158 homolog (chains 8, 9) MQFLTAVSPQSSSTPSWKIETKYSTRVLTGNWTEERRKFIKATEKTPQTIYRKEYVPFPG HRPDQISRWYSKRTVEGLPYKYLITHHQEPSQRYLISTYDDHYNRHNYHPGLPELRTWNR HKLLWLPEKADFPLLGPPTNYGLYEQLKQKWLPPPEATLRESIYTSSYPRPPAGAMSRRE HAIPVPPPRLQPVPHF
>7RRO_6 Meiosis-specific nuclear structural protein 1 (chains A, B) MASIRRTLSFSERHQKLVDINYCKKLHVEALQRLQNQTRDQMVQNENDDRAERKRFLRLL QDEQFELDMEEAIQKAEENKRLRELQLAQEEKLATELAKLKRESLKDEKLRQQVRENSAE LRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIARTMMEEHERLIKEESAAEDKR NQAKAQYSHDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQRLEKMNT TRRYIEEFQKEQALWRKKKREEMEEENRKIIEFAKLQQQREEDRMAKVQESEEKRLQLKN MLTQRLEEMLRQREDLEQVRQELYQEEQAEIYKKKLEEEAEEKLRKQKELKQDFMDQMAL KELILQAAKEEEETFRKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRNQFL ADKQRELEEWQWQQRRQGCINAIVEEERLKLLKEHATKLLGYLPKGVFKNEDDIDMLGEE FRKAYQKRSEICEK
>7RRO_7 Tektin-1 (chains A0, A1, A2, A3, A4) MAKLLQQPPKFLRAEWQIANKNQYHRAEAQRSRSERLVAESQRLVDEIEKTTRKSQSDVN KKLEQRLEEVRFWKKELDDKLEQLVYATEDLLLYQTRLQKALESFKEPLHITEKCLEYRE KRVGIDLVHDEVEQELIKEHEIIRGVMTLLTRTLEETCEQIRLNRSAKYNLEKDLRDKFT AITIDDICFSLNNNSPNIKYSENVVRVEPNSVSLEDWLDFSNTNVEKADKQRNNSLTLKA LVDRILFQTASDLRRQCDVVDTAFKNGLKETKDARDKLALHLDKVMEEIASQEKNIVVLE KAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLIKEVDEITHNVARLKETLAQAHV ELKGLNRRQLALQEEIQIKENTIYIDEVLCVPMRKSIPPRDGDDHGEWAGGSHPEAVC
>7RRO_8 Tubulin alpha-1D chain (chains AA, AC, AE, AG, AI, AK, AM, BA, BC, BE, BG, BI, BK, BM, CA, CC, CE, CG, CI, CK, CM, DA, DC, DE, DG, DI, DK, DM, EC, EE, EG, EI, EK, EM, FC, FE, FG, FI, FK, FM, GC, GE, GG, GI, GK, GM, HC, HE, HG, HI, HK, HM, HO, IC, IE, IG, II, IK, IM, IO, JC, JE, JG, JI, JK, JM, KC, KE, KG, KI, KK, KM, KO, LC, LE, LG, LI, LK, LM, MC, ME, MG, MI, MK, MM, NA, NC, NE, NG, NI, NK, OA, OC, OE, OG, OI, OK, PA, PC, PE, PG, PI, PK, PM, QA, QC, QE, QG, QI, QK, QM, RA, RC, RE, RG, RI, RK, RM, SA, SC, SE, SG, SI, SK, SM, TC, TE, TG, TI, TK, TM, UC, UE, UG, UI, UK, UM, VC, VE, VG, VI, VK, VM, WC, WE, WG, WI, WK, WM) MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLD RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE AREDMAALEKDYEEVGMDSVEGEGEEEEGDEY
>7RRO_9 Tubulin beta-4B chain (chains AB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, DN, EB, ED, EF, EH, EJ, EL, EN, FB, FD, FF, FH, FJ, FL, FN, GB, GD, GF, GH, GJ, GL, GN, HB, HD, HF, HH, HJ, HL, HN, IB, ID, IF, IH, IJ, IL, IN, JB, JD, JF, JH, JJ, JL, JN, KB, KD, KF, KH, KJ, KL, KN, LB, LD, LF, LH, LJ, LL, LN, MB, MD, MF, MH, MJ, ML, MN, N0, NB, ND, NF, NH, NJ, NL, O0, OB, OD, OF, OH, OJ, OL, PB, PD, PF, PH, PJ, PL, QB, QD, QF, QH, QJ, QL, RB, RD, RF, RH, RJ, RL, SB, SD, SF, SH, SJ, SL, TB, TD, TF, TH, TJ, TL, UB, UD, UF, UH, UJ, UL, UN, VB, VD, VF, VH, VJ, VL, VN, WB, WD, WF, WH, WJ, WL, WN) MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS EYQQYQDATAEEEGEFEEEAEEEVA
>7RRO_10 Tektin-2 (chains B0, B1, B2, B3, B4, B5, B6, B7, B8, B9) MATLSVKPSPRFRLPDWQTNSYLLSTNAERQRDASHQIRQEARVLRNETNNQTIWDEHDN RTRLAERIDTVSRWKEMLDKCLTDLDAEIDALAQMKESAEQNLQAKNLPLDVAIECLTLR ESRRDIDVVKDPVEEELHKEVEVIEATKKALQQKISQAFEKLFLLQEARQRLNSDHRGKM ETLDIDRGCLSLNLTSPNISLKINPTRVPNGSTSLQQWDDLSRFNKDHGEAEMKKAIELR EAIALTIAETNNELEAQRVATEFAFRKRLREMEKLYSELKWQEKNTLEEIAELHEDIRHL EEDLRRKLQNLKLCHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQ DALDALYKHLARLQADIACKANSMLLDTKCMDTRRKLTVPAEKFVPEVDTFTRTTNRTLS PLKTCQLELA
>7RRO_11 Uncharacterized protein C1orf189 homolog (chains C) MSMEKMGKVEEHFQRALELKKMVHRWRNSHTHCLWQITLSQRRNPYAILRMQDTMVQELA LANKQLLMVRQAALHQLFEKEHQQYQQELNEKGKAFYMERL
>7RRO_12 Tektin-3 (chains C0, C1, C2, C3, C4, C5, C6, C7, C8, C9, F0, F1, F2, F3, F4) MELLGSTLTATYAHPRPTPTNFLPAISTMASTYRDRFPHYNLTHSLSLPWRPSTYYKAAS NWPTLDPYCTRSQRVSESTMLPFVSNRTTLFTRYTPDDWYRSNLTNFQESNTSRHNSERL RVDTSRLIQDKYQQTRKTQADSTQNLGERVNDIGFWKSEIIHELDAMIGETNELTDIKKR LERALMETEAPLQVARECLFHREKRMGIDLVHDEVEKELLTEVDTILCCQERMKLYLDKA IAQLAANRAAQHELEKDLSDKQSAYRIDDKCHHLRNTSDGVSYFHGVERVDATVSVPESW AKFTDDNILRSQSERAASAKLRDDIQNVLVVTANEMWNQFNKVNLAFTNRIAETADAKNK IQTHLAKTLQEIFQTEMTIESIKKAIVEKSAFLKVAQTRLDERTRRPNIELCRDMAQLRL VNEVYEVDDTIQTLQQRLRDAEDTLQSLAHTKATLEHDLAVKANSLYIDQDKCMSMRRSF PSTLRLVGFC
| ID | Name | Formula | Copies |
|---|---|---|---|
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 149 |
| MG | Magnesium ion | Mg | 149 |
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 153 |
De novo identification of mammalian ciliary motility proteins using cryo-EM. Gui, M., Farley, H., Anujan, P. et al. Cell (2021) 184:5791. DOI 10.1016/j.cell.2021.10.007 · PubMed
Other PDB entries of the same protein (UniProt Q32L77 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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