7TUB: The beta-tubulin folding intermediate IV

The beta-tubulin folding intermediate IV. Determined by electron microscopy at 3.6 Å resolution. Released 28 Dec 2022.

Method: Electron microscopy
Resolution: 3.6 Å
Organism: Homo sapiens
Chains: 9
Atoms: 35,877
Mol. weight: 528.65 kDa
Ligands: AF3, ADP, MG
Released: 28 Dec 2022

Explore 7TUB in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7TUB contains 213 α-helices and 219 β-strands across 9 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 25 helices, 15 β-strands

Element	Residues	Length	Sheet
β-strand	4-9	6	1
α-helix	10-25	16
β-strand	30	1	2
β-strand	36	1	2
α-helix	47-49	3
β-strand	51-54	4	3
β-strand	58-61	4	3
β-strand	63-67	5	1
α-helix	70-78	9
α-helix	87-89	3
β-strand	90-92	3	1
α-helix	101-102	2
α-helix	103-107	5
α-helix	110-124	15
β-strand	132-138	7	1
α-helix	142	1
α-helix	143-147	5
α-helix	148-158	11
β-strand	163-170	8	1
α-helix	171	1
α-helix	173-175	3
α-helix	182-193	12
β-strand	198-203	6	1
α-helix	204-209	6
α-helix	210-215	6
α-helix	222-241	20
α-helix	250-257	8
β-strand	265-266	2	1
β-strand	267-269	3	4
α-helix	276-281	6
α-helix	286-291	6
β-strand	310-318	9	4
α-helix	323-336	14
α-helix	338-340	3
β-strand	350-354	5	4
α-helix	357-358	2
β-strand	364-371	8	4
α-helix	375-389	15
α-helix	396-399	4
α-helix	406-424	19

Chain B: 30 helices, 25 β-strands

Element	Residues	Length	Sheet
α-helix	11-14	4
β-strand	15	1	5
α-helix	16	1
β-strand	20-22	3	6
α-helix	24	1
α-helix	25-29	5
α-helix	30-43	14
α-helix	44-46	3
α-helix	51-52	2
β-strand	53-57	5	7
β-strand	63-66	4	7
α-helix	69-75	7
β-strand	78	1	8
α-helix	81-96	16
α-helix	101-121	21
α-helix	125-142	18
α-helix	143-146	4
β-strand	149-150	2	9
α-helix	157-169	13
α-helix	176-188	13
α-helix	191-192	2
β-strand	202-208	7	10
α-helix	212-214	3
β-strand	216-218	3	10
β-strand	220-223	4	11
β-strand	234	1	11
β-strand	237-242	6	12
β-strand	246	1	13
β-strand	255-259	5	14
α-helix	262-285	24
β-strand	290-293	4	12
β-strand	297	1	13
α-helix	299-307	9
β-strand	311-314	4	12
α-helix	320-328	9
α-helix	338-340	3
α-helix	341-343	3
β-strand	345-347	3	12
β-strand	349-354	6	11
β-strand	359-364	6	11
β-strand	373-379	7	10
α-helix	382-404	23
β-strand	407-410	4	9
α-helix	414-427	14
α-helix	435-443	9
α-helix	444-446	3
α-helix	447-455	9
α-helix	460-472	13
β-strand	478-480	3	15
β-strand	489-491	3	15
α-helix	492-495	4
β-strand	498-500	3	9
α-helix	501-519	19
β-strand	521-526	6	6
α-helix	527-529	3

Chain C: 22 helices, 26 β-strands

Element	Residues	Length	Sheet
β-strand	9	1	8
α-helix	10	1
β-strand	14-17	4	7
α-helix	19-35	17
α-helix	37-39	3
β-strand	46-50	5	16
β-strand	56-59	4	16
α-helix	62-68	7
β-strand	71	1	17
α-helix	76-89	14
α-helix	96-113	18
α-helix	118-139	22
β-strand	141-142	2	18
α-helix	148-161	14
α-helix	169-171	3
α-helix	172-184	13
α-helix	192-194	3
β-strand	195-200	6	19
α-helix	205-207	3
β-strand	209-211	3	19
β-strand	213-217	5	20
α-helix	225-227	3
β-strand	231-232	2	20
β-strand	236-240	5	21
β-strand	244	1	22
β-strand	253-257	5	14
α-helix	260-283	24
β-strand	288-291	4	21
β-strand	295	1	22
α-helix	297-305	9
β-strand	309-312	4	21
α-helix	316-326	11
β-strand	331	1	21
β-strand	343-344	2	21
β-strand	347-353	7	20
β-strand	356-362	7	20
β-strand	370-375	6	19
α-helix	379-401	23
β-strand	404-407	4	18
α-helix	411-424	14
α-helix	431-441	11
α-helix	445-453	9
α-helix	457-470	14
β-strand	485-488	4	23
β-strand	493-496	4	23
β-strand	503-505	3	18
α-helix	506-524	19
β-strand	526-531	6	7

Chain D: 20 helices, 30 β-strands

Element	Residues	Length	Sheet
β-strand	19	1	17
β-strand	25-29	5	16
α-helix	31-47	17
β-strand	58-62	5	24
β-strand	68-71	4	24
α-helix	74-80	7
α-helix	86-101	16
α-helix	106-125	20
α-helix	130-148	19
β-strand	153-154	2	25
α-helix	163-173	11
α-helix	177-181	5
α-helix	182-194	13
β-strand	198	1	26
β-strand	203	1	26
α-helix	206-208	3
β-strand	209-213	5	27
β-strand	216	1	28
α-helix	219-221	3
β-strand	223-225	3	27
β-strand	228-230	3	29
β-strand	234	1	30
β-strand	242-243	2	29
β-strand	246-251	6	30
β-strand	255	1	31
β-strand	264-268	5	14
α-helix	271-294	24
β-strand	299-301	3	30
β-strand	306	1	31
α-helix	308-316	9
β-strand	321-322	2	30
α-helix	327-337	11
β-strand	341-342	2	30
β-strand	354-356	3	30
β-strand	358-363	6	29
β-strand	370-375	6	29
β-strand	383-387	5	27
β-strand	389	1	28
α-helix	392-414	23
β-strand	417-419	3	25
α-helix	424-437	14
α-helix	445-455	11
α-helix	457-466	10
α-helix	470-483	14
β-strand	489	1	32
β-strand	500	1	32
α-helix	501-504	4
β-strand	508-509	2	25
α-helix	510-527	18
β-strand	530-536	7	16

Chain E: 24 helices, 23 β-strands

Element	Residues	Length	Sheet
β-strand	17-19	3	24
α-helix	21-39	19
α-helix	40-42	3
β-strand	49-54	6	33
β-strand	61-64	4	33
α-helix	67-73	7
α-helix	79-94	16
α-helix	99-117	19
α-helix	123-142	20
β-strand	146-147	2	34
α-helix	152-166	15
α-helix	171-175	5
α-helix	176-188	13
α-helix	196-198	3
β-strand	199-203	5	35
β-strand	206	1	36
α-helix	209-211	3
β-strand	213-214	2	35
β-strand	218-220	3	37
β-strand	224	1	37
α-helix	225	1
β-strand	232-240	9	37
β-strand	254-258	5	14
α-helix	262-283	22
β-strand	289-292	4	37
α-helix	298-307	10
β-strand	310-312	3	37
α-helix	317-327	11
β-strand	331-332	2	37
α-helix	341-343	3
β-strand	344-354	11	37
β-strand	357-363	7	37
β-strand	371-375	5	35
β-strand	377	1	36
α-helix	380-402	23
β-strand	405-408	4	34
α-helix	412-425	14
α-helix	432-443	12
α-helix	445-454	10
α-helix	458-470	13
β-strand	476-479	4	38
β-strand	484-487	4	38
α-helix	488-491	4
β-strand	494-496	3	34
α-helix	497-515	19
β-strand	517-522	6	24
α-helix	523-527	5

Chain F: 24 helices, 22 β-strands

Element	Residues	Length	Sheet
α-helix	29-47	19
β-strand	58-62	5	39
β-strand	68-71	4	39
α-helix	74-80	7
α-helix	86-88	3
α-helix	91-101	11
α-helix	108-118	11
α-helix	120-126	7
α-helix	130-151	22
β-strand	153-154	2	40
α-helix	160-169	10
α-helix	175-177	3
α-helix	180-192	13
α-helix	205-207	3
β-strand	208-212	5	41
β-strand	215	1	42
α-helix	218-220	3
β-strand	222-224	3	41
β-strand	226-229	4	43
β-strand	240-248	9	43
β-strand	253	1	44
β-strand	262-266	5	14
α-helix	269-292	24
β-strand	297-301	5	43
β-strand	309	1	44
α-helix	311-319	9
β-strand	323-328	6	43
α-helix	333-340	8
α-helix	348-350	3
α-helix	353-355	3
β-strand	357-366	10	43
β-strand	372-379	8	43
β-strand	386-390	5	41
β-strand	392	1	42
α-helix	395-417	23
β-strand	420-423	4	40
α-helix	427-442	16
α-helix	447-457	11
α-helix	460-468	9
α-helix	473-484	12
β-strand	491-494	4	45
β-strand	499-502	4	45
α-helix	504-506	3
β-strand	509-511	3	40
α-helix	512-529	18
β-strand	532-538	7	33

Chain G: 24 helices, 27 β-strands

Element	Residues	Length	Sheet
β-strand	9-13	5	39
α-helix	15-32	18
α-helix	33-35	3
β-strand	42-46	5	46
β-strand	54-55	2	46
α-helix	58-64	7
α-helix	70-85	16
α-helix	90-109	20
α-helix	114-131	18
β-strand	137-138	2	47
α-helix	144-156	13
α-helix	165-177	13
β-strand	181-182	2	48
β-strand	188-189	2	48
β-strand	196-199	4	49
α-helix	205-207	3
β-strand	210-212	3	49
β-strand	213-216	4	50
β-strand	228-229	2	50
β-strand	232-237	6	50
β-strand	241	1	51
β-strand	250-254	5	14
α-helix	257-259	3
α-helix	260-279	20
β-strand	285-288	4	50
β-strand	292	1	51
α-helix	294-303	10
β-strand	306-308	3	50
α-helix	313-323	11
β-strand	328	1	50
β-strand	332	1	52
β-strand	338	1	52
α-helix	342-344	3
β-strand	346-356	11	50
β-strand	359-367	9	50
β-strand	373-377	5	49
α-helix	382-404	23
β-strand	407-410	4	47
α-helix	414-426	13
α-helix	427-429	3
α-helix	434-445	12
α-helix	447-455	9
α-helix	460-475	16
α-helix	478-484	7
β-strand	489	1	53
β-strand	494	1	53
α-helix	498-501	4
β-strand	504-506	3	47
α-helix	507-525	19
β-strand	527-533	7	39
α-helix	534-535	2

Chain H: 23 helices, 26 β-strands

Element	Residues	Length	Sheet
β-strand	15-18	4	46
α-helix	20-37	18
α-helix	45-46	2
β-strand	47-51	5	54
β-strand	57-60	4	54
α-helix	63-67	5
α-helix	75-91	17
α-helix	97-107	11
α-helix	110-113	4
α-helix	119-139	21
β-strand	142-143	2	55
α-helix	149-160	12
α-helix	164-168	5
α-helix	169-183	15
β-strand	185-186	2	56
β-strand	192-193	2	56
β-strand	199-206	8	57
α-helix	209-211	3
β-strand	213-215	3	57
β-strand	218-220	3	58
β-strand	232-233	2	58
β-strand	238-241	4	59
β-strand	245	1	60
β-strand	254-258	5	14
α-helix	261-283	23
β-strand	289-291	3	59
β-strand	296	1	60
α-helix	298-306	9
β-strand	310-312	3	59
α-helix	317-327	11
β-strand	331-332	2	59
α-helix	335-337	3
β-strand	344	1	59
β-strand	349-354	6	58
β-strand	359-364	6	58
β-strand	372-378	7	57
α-helix	381-403	23
β-strand	406-409	4	55
α-helix	413-426	14
α-helix	434-442	9
α-helix	443-445	3
α-helix	446-455	10
α-helix	461-470	10
β-strand	478-480	3	61
β-strand	487-489	3	61
α-helix	490-493	4
β-strand	496-498	3	55
α-helix	499-516	18
β-strand	519-524	6	46

1 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Tubulin beta chain	A	protein	444	Homo sapiens	P07437 (AlphaFold model)
T-complex protein 1 subunit theta	B	protein	547	Homo sapiens	P50990 (AlphaFold model)
T-complex protein 1 subunit eta	C	protein	553	Homo sapiens	Q99832 (AlphaFold model)
T-complex protein 1 subunit epsilon	D	protein	541	Homo sapiens	P48643 (AlphaFold model)
T-complex protein 1 subunit beta	E	protein	535	Homo sapiens	P78371
T-complex protein 1 subunit delta	F	protein	539	Homo sapiens	P50991
T-complex protein 1 subunit alpha	G	protein	556	Homo sapiens	P17987
T-complex protein 1 subunit gamma	H	protein	545	Homo sapiens	P49368
T-complex protein 1 subunit zeta	I	protein	531	Homo sapiens	P40227

Sequence of entity 1 (A), FASTA

>7TUB_1 Tubulin beta chain (chains A)
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM
AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATAEEEEDFGEEAEEEA

Sequence of entity 2 (B), FASTA

>7TUB_2 T-complex protein 1 subunit theta (chains B)
MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHL
EKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLR
IGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLA
KLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIA
VYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADM
ALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQV
VVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELA
KQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGL
DIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKK
DWDDDQN

Sequence of entity 3 (C), FASTA

>7TUB_3 T-complex protein 1 subunit eta (chains C)
MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISN
DGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQI
IIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV
DAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALL
NVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVAT
QYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNF
FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL
RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGSHHHHHHG
SGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAP
TAAGRGRGRGRPH

Sequence of entity 4 (D), FASTA

>7TUB_4 T-complex protein 1 subunit epsilon (chains D)
MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKM
MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNS
CHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP
KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA
ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ
EISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVY
GGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR
QVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE
E

Sequence of entity 5 (E), FASTA

>7TUB_5 T-complex protein 1 subunit beta (chains E)
MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA
NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP
EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI
HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA
VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM
REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC

Sequence of entity 6 (F), FASTA

>7TUB_6 T-complex protein 1 subunit delta (chains F)
MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM
IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC
TKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYS
SLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITR
VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLI
QKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAE
LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRA
LIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTEL
RNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR

Sequence of entity 7 (G), FASTA

>7TUB_7 T-complex protein 1 subunit alpha (chains G)
MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT
ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG
YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK
YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS
LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF
VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE
LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS
IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER
KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD
KHGSYEDAVHSGALND

Sequence of entity 8 (H), FASTA

>7TUB_8 T-complex protein 1 subunit gamma (chains H)
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
DAGQE

Sequence of entity 9 (I), FASTA

>7TUB_9 T-complex protein 1 subunit zeta (chains I)
MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSFLKG

Ligands and cofactors

ID	Name	Formula	Copies
AF3	Aluminum fluoride	Al F3	8
ADP	Adenosine-5'-diphosphate	C10 H15 N5 O10 P2	8
MG	Magnesium ion	Mg	8

Primary citation

Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Gestaut, D., Zhao, Y., Park, J. et al. Cell (2022) 185:4770-4787.e20. DOI 10.1016/j.cell.2022.11.014 · PubMed

Other PDB entries of the same protein (UniProt P07437 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3QNZ 2.2 Å, Orthorhombic form of IgG1 Fab fragment (in complex with antigenic tubulin peptide)…
3QO0 2.3 Å, Monoclinic form of IgG1 Fab fragment (in complex with antigenic peptide) sharing same Fv…
8BPO 2.8 Å, Structure of rabbit 80S ribosome translating beta-tubulin in complex with…
7TTT 2.9 Å, The beta-tubulin folding intermediate III
8V2J 2.9 Å, Structure of alpha1B and betaI/IVb microtubule bound to GDP
9COC 2.9 Å, Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GDP
7TRG 3.0 Å, The beta-tubulin folding intermediate I
7X0S 3.1 Å, Human TRiC-tubulin-S3
9BP6 3.1 Å, Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
9CMM 3.1 Å, Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
9HQ4 3.28 Å, TTLL11 bound to microtubule
7TTN 3.3 Å, The beta-tubulin folding intermediate II

Browse structure collections

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