7Z31: Yeast RNA Polymerase III-Ty1 integrase complex

Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore). Determined by electron microscopy at 2.76 Å resolution. Released 5 Apr 2023.

Method: Electron microscopy
Resolution: 2.76 Å
Organism: Saccharomyces cerevisiae S288C
Chains: 19
Atoms: 40,156
Mol. weight: 763.65 kDa
Ligands: MG, ZN
Released: 5 Apr 2023

Explore 7Z31 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7Z31 contains 239 α-helices and 265 β-strands across 18 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 80 helices, 56 β-strands

Element	Residues	Length	Sheet
β-strand	4	1	1
α-helix	5-6	2
β-strand	11-20	10	2
α-helix	21-22	2
α-helix	23-29	7
β-strand	32-33	2	3
α-helix	42-44	3
α-helix	56-58	3
β-strand	82-85	4	3
α-helix	96-103	8
β-strand	106	1	4
β-strand	113	1	4
α-helix	121-127	7
α-helix	134-150	17
α-helix	165	1
β-strand	166	1	5
α-helix	167	1
β-strand	178-180	3	5
α-helix	192-205	14
α-helix	211-214	4
β-strand	220-222	3	5
α-helix	224-233	10
α-helix	239-242	4
β-strand	260-263	4	3
α-helix	264-265	2
α-helix	270-272	3
α-helix	280-281	2
α-helix	284-305	22
α-helix	309-327	19
α-helix	353-357	5
α-helix	364-368	5
β-strand	371-373	3	6
β-strand	376-383	8	7
β-strand	391-395	5	7
α-helix	396-399	4
β-strand	403-407	5	8
α-helix	408	1
α-helix	413-422	10
β-strand	430-434	5	8
β-strand	441-443	3	8
α-helix	449-455	7
β-strand	461-465	5	8
α-helix	466	1
β-strand	471-475	5	7
α-helix	482-484	3
β-strand	485-493	9	7
β-strand	498-500	3	7
α-helix	502-504	3
α-helix	505-508	4
β-strand	516-520	5	7
α-helix	525-534	10
β-strand	536	1	7
α-helix	538-540	3
β-strand	542	1	9
β-strand	549	1	9
α-helix	555-565	11
β-strand	570-571	2	10
α-helix	573-583	11
α-helix	592-595	4
β-strand	597-599	3	11
β-strand	603	1	11
β-strand	604-605	2	10
α-helix	606-614	9
β-strand	626-629	4	12
α-helix	634-636	3
α-helix	643-645	3
β-strand	651-655	5	12
β-strand	658-661	4	12
α-helix	666-669	4
α-helix	677-685	9
α-helix	687-708	22
β-strand	711	1	13
α-helix	714-716	3
α-helix	718-720	3
α-helix	721-747	27
α-helix	758-784	27
α-helix	786	1
α-helix	790-797	8
α-helix	803-810	8
β-strand	813-815	3	14
β-strand	818	1	15
β-strand	821	1	15
β-strand	827	1	16
β-strand	830	1	16
α-helix	843-845	3
β-strand	847-848	2	14
α-helix	858-880	23
α-helix	885-893	9
β-strand	897-898	2	17
β-strand	904-905	2	17
β-strand	911-913	3	17
α-helix	916-918	3
β-strand	921	1	18
α-helix	923-925	3
α-helix	935-945	11
α-helix	952-955	4
α-helix	956-966	11
α-helix	969-973	5
β-strand	977	1	19
β-strand	983	1	19
α-helix	999-1025	27
α-helix	1038-1040	3
α-helix	1052-1059	8
α-helix	1064-1081	18
β-strand	1082	1	18
α-helix	1083-1084	2
α-helix	1089-1098	10
α-helix	1100-1103	4
α-helix	1123-1131	9
β-strand	1141-1145	5	20
α-helix	1150-1154	5
α-helix	1155-1160	6
α-helix	1166-1170	5
β-strand	1172-1173	2	21
β-strand	1176-1177	2	22
β-strand	1182-1187	6	22
α-helix	1190-1195	6
α-helix	1203-1216	14
β-strand	1222-1224	3	22
β-strand	1229-1233	5	22
α-helix	1255-1266	12
β-strand	1281-1285	5	20
β-strand	1291-1295	5	20
α-helix	1300-1305	6
β-strand	1309-1316	8	20
α-helix	1319-1325	7
α-helix	1328-1344	17
α-helix	1352-1363	12
α-helix	1383-1389	7
α-helix	1392-1401	10
β-strand	1407	1	2
α-helix	1411-1417	7
α-helix	1419-1421	3
α-helix	1424-1426	3
β-strand	1429-1432	4	1
α-helix	1448-1455	8

Chain B: 53 helices, 86 β-strands

Element	Residues	Length	Sheet
α-helix	40-43	4
α-helix	44-46	3
α-helix	47-54	8
α-helix	60-67	8
α-helix	68-72	5
α-helix	73-79	7
β-strand	82-83	2	23
β-strand	93-100	8	23
α-helix	109-114	6
α-helix	115-121	7
β-strand	126-135	10	23
β-strand	137	1	24
β-strand	141	1	24
β-strand	147-153	7	23
α-helix	169-173	5
β-strand	185-187	3	25
β-strand	190-194	5	25
α-helix	195	1
β-strand	196-200	5	26
α-helix	201	1
β-strand	205-208	4	27
β-strand	217-223	7	27
β-strand	228-233	6	27
β-strand	235-236	2	28
β-strand	239-240	2	28
β-strand	241-242	2	29
β-strand	243-244	2	27
β-strand	247	1	30
α-helix	250	1
β-strand	251-252	2	29
α-helix	253-259	7
α-helix	267-272	6
α-helix	277-293	17
α-helix	298-306	9
β-strand	309	1	30
α-helix	317-319	3
α-helix	322-324	3
α-helix	325-330	6
α-helix	343-361	19
α-helix	372-374	3
β-strand	375-378	4	26
α-helix	380-407	28
α-helix	420-425	6
α-helix	427-439	13
β-strand	442-444	3	31
β-strand	449-451	3	31
β-strand	455-457	3	25
α-helix	463-469	7
β-strand	472-475	4	26
α-helix	476	1
α-helix	489-490	2
α-helix	491-493	3
β-strand	497	1	32
β-strand	511-513	3	26
β-strand	514	1	32
β-strand	519-520	2	33
α-helix	526-535	10
β-strand	539	1	34
β-strand	553-557	5	34
β-strand	560-565	6	34
α-helix	568-580	13
β-strand	589-593	5	34
β-strand	598-602	5	34
β-strand	608-614	7	33
β-strand	615-616	2	35
β-strand	619-620	2	35
α-helix	625-632	8
α-helix	637-642	6
β-strand	646-650	5	33
α-helix	651-654	4
β-strand	659-660	2	33
α-helix	663-665	3
β-strand	672-673	2	33
α-helix	677-680	4
α-helix	685-687	3
α-helix	691-693	3
β-strand	694	1	36
α-helix	696-706	11
β-strand	709	1	37
β-strand	711	1	38
β-strand	724-728	5	38
β-strand	732	1	39
β-strand	736-737	2	40
α-helix	739-743	5
β-strand	753-759	7	41
β-strand	760	1	13
β-strand	771-774	4	41
β-strand	785-795	11	38
β-strand	797-798	2	42
β-strand	802-803	2	42
β-strand	805	1	43
β-strand	811	1	44
α-helix	816	1
β-strand	817	1	44
α-helix	818	1
α-helix	819-821	3
β-strand	829	1	45
β-strand	832	1	46
β-strand	835-836	2	38
β-strand	841-843	3	45
β-strand	846-848	3	43
β-strand	866-868	3	43
β-strand	871-872	2	45
β-strand	879-888	10	38
β-strand	894-904	11	38
β-strand	911-913	3	47
β-strand	920-921	2	47
β-strand	922-926	5	41
α-helix	928-930	3
β-strand	933	1	48
β-strand	942-944	3	41
α-helix	948-952	5
β-strand	954	1	36
α-helix	955-970	16
β-strand	974-975	2	40
α-helix	984-993	10
β-strand	1001-1002	2	41
β-strand	1005	1	48
β-strand	1012	1	48
α-helix	1013	1
β-strand	1017-1024	8	41
β-strand	1025-1026	2	47
β-strand	1027	1	37
α-helix	1031-1033	3
β-strand	1036-1038	3	7
β-strand	1043	1	49
β-strand	1050	1	49
α-helix	1058-1059	2
β-strand	1060-1062	3	6
α-helix	1064-1073	10
α-helix	1076-1079	4
α-helix	1080-1085	6
β-strand	1089-1095	7	50
β-strand	1101	1	50
β-strand	1103	1	51
β-strand	1106	1	51
β-strand	1116-1122	7	50
α-helix	1123-1134	12
β-strand	1137-1145	9	2

Chain C: 15 helices, 22 β-strands

Element	Residues	Length	Sheet
β-strand	4-7	4	52
β-strand	12-13	2	52
α-helix	36-39	4
β-strand	41-47	7	52
β-strand	51-57	7	52
α-helix	61-69	9
α-helix	70-74	5
β-strand	77-88	12	53
α-helix	94-103	10
α-helix	105	1
β-strand	106	1	54
α-helix	114-116	3
α-helix	122-124	3
β-strand	132-139	8	53
β-strand	141-142	2	55
α-helix	153-156	4
β-strand	157-158	2	55
β-strand	161-163	3	56
α-helix	164-166	3
β-strand	168-170	3	53
α-helix	175-178	4
β-strand	186	1	54
β-strand	192-195	4	56
β-strand	201-211	11	53
α-helix	217-219	3
β-strand	222-226	5	52
β-strand	229-235	7	52
β-strand	240	1	57
α-helix	242-249	8
β-strand	256-258	3	58
β-strand	264	1	57
β-strand	265-267	3	58
α-helix	279-281	3
β-strand	289-304	16	52
α-helix	310-330	21
α-helix	332-333	2
β-strand	334	1	59

Chain D: 10 helices, 2 β-strands

Element	Residues	Length	Sheet
β-strand	3-5	3	1
β-strand	10	1	1
α-helix	15-26	12
α-helix	30-33	4
α-helix	56-67	12
α-helix	69-70	2
α-helix	100-104	5
α-helix	107-110	4
α-helix	120-123	4
α-helix	131-137	7
α-helix	141-144	4
α-helix	152-157	6

Chain E: 14 helices, 12 β-strands

Element	Residues	Length	Sheet
α-helix	3-27	25
α-helix	32-35	4
α-helix	39-45	7
β-strand	47	1	60
α-helix	52	1
β-strand	53	1	60
α-helix	54	1
β-strand	60-62	3	61
α-helix	66-71	6
β-strand	78-82	5	61
β-strand	87	1	62
α-helix	90-103	14
β-strand	107-112	6	61
β-strand	115	1	62
α-helix	120-123	4
β-strand	132-136	5	61
α-helix	138-140	3
α-helix	144-146	3
β-strand	152-155	4	63
α-helix	156-157	2
α-helix	158-167	10
α-helix	172-174	3
β-strand	177-178	2	63
α-helix	183-187	5
β-strand	195-201	7	63
β-strand	207-214	8	63

Chain F: 3 helices, 5 β-strands

Element	Residues	Length	Sheet
β-strand	73	1	1
α-helix	74-75	2
β-strand	84	1	64
α-helix	87-102	16
α-helix	117-126	10
β-strand	133-137	5	1
β-strand	143-147	5	1
β-strand	152	1	64

Chain G: 4 helices, 13 β-strands

Element	Residues	Length	Sheet
β-strand	3	1	1
β-strand	6-13	8	1
α-helix	15-18	4
α-helix	22-33	12
β-strand	38-39	2	1
β-strand	43-54	12	1
α-helix	55-56	2
β-strand	57-58	2	1
β-strand	66-77	12	1
β-strand	87-88	2	65
β-strand	91-93	3	66
β-strand	96-99	4	66
β-strand	108-109	2	66
β-strand	145-146	2	65
β-strand	154	1	67
α-helix	163-172	10
β-strand	195	1	67

Chain H: 1 helix, 11 β-strands

Element	Residues	Length	Sheet
β-strand	4-16	13	11
β-strand	23-30	8	11
β-strand	37-43	7	11
β-strand	54-60	7	11
β-strand	64	1	68
α-helix	81-83	3
β-strand	88	1	68
β-strand	95-98	4	11
β-strand	100-108	9	11
β-strand	111-117	7	11
β-strand	122-127	6	11
β-strand	141-145	5	11

10 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase III subunit RPC1	A	protein	1460	Saccharomyces cerevisiae S288C	P04051 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC2	B	protein	1149	Saccharomyces cerevisiae S288C	P22276 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC1	C	protein	335	Saccharomyces cerevisiae S288C	P07703 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC9	D	protein	161	Saccharomyces cerevisiae S288C	P47076 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	215	Saccharomyces cerevisiae S288C	P20434
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	155	Saccharomyces cerevisiae S288C	P20435
DNA-directed RNA polymerase III subunit RPC8	G	protein	212	Saccharomyces cerevisiae S288C	P35718
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	146	Saccharomyces cerevisiae S288C	P20436
DNA-directed RNA polymerase III subunit RPC10	I	protein	110	Saccharomyces cerevisiae S288C	Q04307
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	70	Saccharomyces cerevisiae S288C	P22139
DNA-directed RNA polymerases I and III subunit RPAC2	K	protein	142	Saccharomyces cerevisiae S288C	P28000
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	70	Saccharomyces cerevisiae S288C	P40422

7 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>7Z31_1 DNA-directed RNA polymerase III subunit RPC1 (chains A)
MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGV
SSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDK
RQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIH
DTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVKRCMDDLNPLKTLNLFKQIKSADCE
LLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIK
AGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGK
QGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELI
VNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSL
HRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNN
LLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLSMMSDGIEHFDIPPPAIMKP
YYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQIL
SGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPA
DDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDV
CINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSK
TPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQY
DNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIM
ETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALA
NLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRK
ARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPI
INAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLEL
TIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRM
QQLRRALPDVVVKGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVL
EVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMR
DSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKD
LVPKRCLFESLSNEAALKAN

Sequence of entity 2 (B), FASTA

>7Z31_2 DNA-directed RNA polymerase III subunit RPC2 (chains B)
MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQ
HLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRL
RDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLD
PGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKI
YLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQ
ALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAM
YNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALL
SINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKS
RKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVED
ITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVH
IATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIA
LYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKR
IDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDR
GFGRCETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQ
IYINKSVPTNSADAPNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLL
RQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIE
LISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFG
PIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLL
ERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPR
LRLEDIFQQ

Sequence of entity 3 (C), FASTA

>7Z31_3 DNA-directed RNA polymerases I and III subunit RPAC1 (chains C)
MSNIVGIEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINID
TSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNL
PDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFA
DCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIK
GESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIF
NVESAGAMTPEEIFFKSVRILKNKAEYLKNCPITQ

Sequence of entity 4 (D), FASTA

>7Z31_4 DNA-directed RNA polymerase III subunit RPC9 (chains D)
MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITR
NVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEK
LQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA

Sequence of entity 5 (E), FASTA

>7Z31_5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>7Z31_6 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>7Z31_7 DNA-directed RNA polymerase III subunit RPC8 (chains G)
MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLK
PGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCY
YTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEG
KNEETPQNEKPPAYALLGSCQTDGMGLVSWWE

Sequence of entity 8 (H), FASTA

>7Z31_8 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>7Z31_9 DNA-directed RNA polymerase III subunit RPC10 (chains I)
MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRKKLPRKEVDDVLGGGWD
NVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVNCGHRWKEN

Sequence of entity 10 (J), FASTA

>7Z31_10 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>7Z31_11 DNA-directed RNA polymerases I and III subunit RPAC2 (chains K)
MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTS
ASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKG
LKDLMDLCDVVESKFTEKIKSM

Sequence of entity 12 (L), FASTA

>7Z31_12 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
XXXXXXXXXXXXXXXXXXXXXXXXXXLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
MG	Magnesium ion	Mg	1
ZN	Zinc ion	Zn	6

Primary citation

Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nguyen, P.Q., Huecas, S., Asif-Laidin, A. et al. Nat Commun (2023) 14:1729-1729. DOI 10.1038/s41467-023-37109-4 · PubMed

Other PDB entries of the same protein (UniProt P04051 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7Z0H 2.6 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
7Z1O 2.7 Å, Structure of yeast RNA Polymerase III PTC + NTPs
7Z1L 2.8 Å, Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
7Z30 2.9 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11…
7Z2Z 3.07 Å, Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
8BWS 3.2 Å, Structure of yeast RNA Polymerase III elongation complex at 3.3 A
6TUT 3.25 Å, Cryo-EM structure of the RNA Polymerase III-Maf1 complex
6EU3 3.3 Å, Apo RNA Polymerase III - closed conformation (cPOL3)
6EU1 3.4 Å, RNA Polymerase III - open DNA complex (OC-POL3).
6EU2 3.4 Å, Apo RNA Polymerase III - open conformation (oPOL3)
7Z1M 3.4 Å, Structure of yeast RNA Polymerase III Elongation Complex (EC)
6F40 3.7 Å, RNA Polymerase III open complex

Browse structure collections

About this viewer

MolViewer shows 7Z31 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.