7ZI4: Human INO80 complex

Cryo-EM structure of the human INO80 complex bound to a WT nucleosome. Determined by electron microscopy at 3.2 Å resolution. Released 19 Apr 2023.

Method: Electron microscopy
Resolution: 3.2 Å
Organisms: Homo sapiens, synthetic construct
Chains: 20
Atoms: 42,294
Mol. weight: 820.3 kDa
Ligands: ADP, BEF, ZN
Released: 19 Apr 2023

Explore 7ZI4 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7ZI4 contains 227 α-helices and 216 β-strands across 18 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 24 helices, 25 β-strands

Element	Residues	Length	Sheet
α-helix	13-14	2
β-strand	15	1	1
β-strand	26	1	2
β-strand	32	1	2
β-strand	35-36	2	3
β-strand	39-40	2	3
α-helix	43-58	16
β-strand	61	1	4
β-strand	65-69	5	5
α-helix	76-86	11
β-strand	93-97	5	5
α-helix	98-100	3
α-helix	108-118	11
β-strand	120-140	21	6
β-strand	157-163	7	6
β-strand	166-172	7	6
α-helix	174-182	9
β-strand	189-194	6	6
β-strand	200-206	7	6
α-helix	207-209	3
β-strand	215	1	7
β-strand	220-221	2	6
α-helix	222-224	3
β-strand	229-236	8	6
β-strand	239	1	6
α-helix	240-248	9
α-helix	260-262	3
α-helix	265-266	2
α-helix	270-272	3
α-helix	273-288	16
β-strand	292-296	5	6
β-strand	298-302	5	5
α-helix	304-306	3
α-helix	309-319	11
β-strand	326-331	6	5
β-strand	333	1	8
β-strand	336-337	2	9
α-helix	338	1
β-strand	345-346	2	9
α-helix	347-349	3
α-helix	352-357	6
β-strand	359-362	4	5
α-helix	368-382	15
α-helix	388-400	13
α-helix	404-419	16
α-helix	427-436	10
β-strand	438	1	10
α-helix	440-449	10
α-helix	451-453	3

Chain B: 18 helices, 23 β-strands

Element	Residues	Length	Sheet
α-helix	16-18	3
β-strand	22	1	11
α-helix	38-40	3
β-strand	42-43	2	12
β-strand	46-47	2	12
α-helix	50-65	16
β-strand	68	1	1
β-strand	71-76	6	10
α-helix	83-94	12
β-strand	100-104	5	10
α-helix	115-123	9
β-strand	128-147	20	7
β-strand	159-164	6	7
β-strand	169-174	6	7
α-helix	176-184	9
β-strand	191-196	6	7
β-strand	202-207	6	7
β-strand	224	1	7
β-strand	233-243	11	7
α-helix	244-250	7
α-helix	259-262	4
α-helix	270-286	17
β-strand	290-292	3	7
β-strand	295-299	5	10
α-helix	306-315	10
β-strand	323-328	6	10
β-strand	333-334	2	13
α-helix	335	1
β-strand	341-342	2	13
α-helix	343-345	3
α-helix	348-353	6
β-strand	354-358	5	10
α-helix	364-378	15
β-strand	382	1	14
α-helix	385-396	12
α-helix	400-415	16
β-strand	421	1	14
α-helix	424-432	9
β-strand	434	1	15
α-helix	436-444	9
β-strand	451	1	16

Chain C: 20 helices, 26 β-strands

Element	Residues	Length	Sheet
β-strand	3-5	3	17
α-helix	10-14	5
β-strand	15	1	18
β-strand	26	1	19
β-strand	32	1	19
β-strand	35-36	2	20
β-strand	39-40	2	20
α-helix	43-58	16
β-strand	61	1	11
β-strand	65-69	5	15
α-helix	76-87	12
β-strand	93-97	5	15
α-helix	108-119	12
β-strand	120-142	23	21
β-strand	154-162	9	21
β-strand	167-172	6	21
α-helix	174-182	9
β-strand	189-194	6	21
β-strand	200-206	7	21
β-strand	220-221	2	21
α-helix	222-224	3
β-strand	229-239	11	21
α-helix	240-248	9
α-helix	256-261	6
α-helix	273-288	16
β-strand	293-296	4	21
β-strand	298-302	5	15
α-helix	304-306	3
α-helix	309-319	11
β-strand	326-331	6	15
β-strand	333	1	16
β-strand	335-337	3	22
α-helix	338	1
β-strand	345-347	3	22
α-helix	352-355	4
β-strand	358-362	5	15
α-helix	365-367	3
α-helix	368-382	15
β-strand	386	1	23
α-helix	388-400	13
α-helix	403-408	6
α-helix	410-419	10
β-strand	425	1	23
α-helix	427-436	10
β-strand	438	1	24
α-helix	442-449	8

Chain D: 19 helices, 24 β-strands

Element	Residues	Length	Sheet
β-strand	22	1	25
β-strand	33	1	26
β-strand	39	1	26
β-strand	42-43	2	27
β-strand	46-47	2	27
α-helix	50-65	16
β-strand	68	1	18
β-strand	72-76	5	24
α-helix	83-94	12
β-strand	100-104	5	24
α-helix	115-124	10
β-strand	128-150	23	28
β-strand	158-164	7	28
β-strand	169-174	6	28
α-helix	178-185	8
β-strand	191-196	6	28
β-strand	202-207	6	28
α-helix	210-212	3
β-strand	224	1	28
β-strand	233-243	11	28
α-helix	244-252	9
α-helix	259-262	4
α-helix	270-286	17
β-strand	290-292	3	28
β-strand	295-299	5	24
α-helix	301-303	3
α-helix	306-315	10
β-strand	323-328	6	24
β-strand	333-334	2	29
α-helix	335	1
β-strand	341-342	2	29
α-helix	343-345	3
α-helix	348-351	4
β-strand	354-358	5	24
α-helix	364-378	15
β-strand	382	1	30
α-helix	384-396	13
α-helix	399-415	17
β-strand	421	1	30
α-helix	423-432	10
β-strand	434	1	31
α-helix	436-443	8
α-helix	444-446	3

Chain E: 25 helices, 28 β-strands

Element	Residues	Length	Sheet
α-helix	13-14	2
β-strand	15	1	32
β-strand	26	1	33
α-helix	31	1
β-strand	32	1	33
α-helix	33	1
β-strand	35-36	2	34
β-strand	39-40	2	34
α-helix	43-58	16
β-strand	61	1	25
β-strand	65-69	5	31
α-helix	76-87	12
β-strand	93-97	5	31
α-helix	108-118	11
β-strand	120-139	20	35
α-helix	141	1
β-strand	142-143	2	28
β-strand	152-154	3	28
β-strand	157-162	6	35
β-strand	167-172	6	35
α-helix	175-180	6
β-strand	189-194	6	35
β-strand	200-205	6	35
β-strand	206	1	36
α-helix	219-220	2
β-strand	221	1	36
α-helix	222-224	3
β-strand	229-236	8	35
β-strand	239	1	35
α-helix	240-248	9
α-helix	256-263	8
α-helix	265-266	2
α-helix	273-288	16
β-strand	292-296	5	35
β-strand	298-302	5	31
α-helix	304-306	3
α-helix	309-319	11
β-strand	326-331	6	31
β-strand	335-337	3	37
α-helix	338	1
β-strand	345-347	3	37
α-helix	352-355	4
β-strand	358-362	5	31
α-helix	368-382	15
β-strand	386	1	38
α-helix	388-401	14
α-helix	403-408	6
α-helix	410-420	11
β-strand	425	1	38
α-helix	427-436	10
β-strand	438	1	39
α-helix	440-449	10
α-helix	451-453	3

Chain F: 19 helices, 22 β-strands

Element	Residues	Length	Sheet
β-strand	22	1	4
β-strand	42-43	2	40
β-strand	46-47	2	40
α-helix	50-65	16
β-strand	68	1	32
β-strand	71-76	6	39
α-helix	83-94	12
β-strand	100-104	5	39
α-helix	105-108	4
α-helix	115-124	10
β-strand	128-147	20	41
β-strand	159-164	6	41
β-strand	169-172	4	41
α-helix	176-185	10
β-strand	191-195	5	41
β-strand	202-207	6	41
α-helix	209-211	3
β-strand	217	1	6
β-strand	224	1	41
α-helix	226-228	3
β-strand	233-243	11	41
α-helix	244-252	9
α-helix	257-262	6
α-helix	270-286	17
β-strand	289-292	4	41
β-strand	295-299	5	39
α-helix	301-303	3
α-helix	306-315	10
β-strand	323-328	6	39
β-strand	332-334	3	42
α-helix	335	1
β-strand	341-343	3	42
α-helix	348-351	4
β-strand	356-358	3	39
α-helix	364-377	14
α-helix	384-396	13
α-helix	399-415	17
α-helix	423-432	10
β-strand	434	1	5
α-helix	436-445	10
β-strand	451	1	8

Chain G: 39 helices, 19 β-strands

Element	Residues	Length	Sheet
α-helix	520-535	16
α-helix	549-559	11
β-strand	570-573	4	43
α-helix	579-589	11
β-strand	595	1	43
α-helix	602-612	11
β-strand	626-629	4	43
α-helix	631-636	6
α-helix	638-642	5
β-strand	648-650	3	43
α-helix	654-656	3
α-helix	663-669	7
β-strand	676-677	2	43
α-helix	688-698	11
α-helix	706-711	6
α-helix	730-739	10
β-strand	759-765	7	17
α-helix	769-779	11
α-helix	810-817	8
β-strand	831-833	3	44
α-helix	835-837	3
β-strand	838-839	2	45
α-helix	842-847	6
α-helix	850-853	4
α-helix	855-863	9
α-helix	869-877	9
α-helix	890-893	4
α-helix	898-906	9
α-helix	909-932	24
α-helix	959-964	6
α-helix	966-971	6
β-strand	980-984	5	46
β-strand	986-989	4	28
β-strand	996-998	3	28
β-strand	1002-1005	4	46
α-helix	1006-1007	2
α-helix	1008-1010	3
β-strand	1017-1019	3	44
α-helix	1020-1022	3
β-strand	1024-1025	2	45
α-helix	1029-1038	10
α-helix	1044-1052	9
α-helix	1055-1063	9
α-helix	1064-1066	3
α-helix	1070-1073	4
α-helix	1090-1092	3
α-helix	1095-1099	5
α-helix	1101-1116	16
β-strand	1120-1124	5	17
α-helix	1127-1139	13
β-strand	1145-1146	2	17
α-helix	1153-1163	11
β-strand	1171-1175	5	17
α-helix	1176-1180	5
β-strand	1190-1193	4	17
α-helix	1203-1210	8
β-strand	1220-1226	7	17
α-helix	1231-1248	18

Chain H: 15 helices, 20 β-strands

Element	Residues	Length	Sheet
β-strand	33-36	4	51
β-strand	41-46	6	51
β-strand	58-62	5	51
β-strand	65	1	52
β-strand	66-67	2	53
β-strand	74-75	2	53
β-strand	95	1	52
β-strand	98-99	2	54
β-strand	102-103	2	54
α-helix	107-119	13
β-strand	132	1	51
α-helix	144-156	13
β-strand	160-161	2	51
α-helix	166-174	9
β-strand	183-188	6	55
β-strand	193-198	6	55
β-strand	203	1	55
β-strand	209-211	3	55
α-helix	215-229	15
α-helix	239-248	10
α-helix	256-262	7
α-helix	266-269	4
β-strand	274	1	56
β-strand	444	1	56
α-helix	447-450	4
α-helix	452-454	3
α-helix	458-460	3
α-helix	468-476	9
α-helix	481-488	8
β-strand	491-495	5	55
α-helix	503-514	12
β-strand	523-525	3	55
α-helix	532-542	11
β-strand	552-553	2	51
α-helix	556-559	4

10 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
RuvB-like 1	A, C, E	protein	456	Homo sapiens	Q9Y265 (AlphaFold model)
RuvB-like 2	B, D, F	protein	463	Homo sapiens	Q9Y230 (AlphaFold model)
Chromatin-remodeling ATPase INO80	G	protein	1556	Homo sapiens	Q9ULG1 (AlphaFold model)
Histone H4	J, N	protein	103	Homo sapiens	P62805 (AlphaFold model)
INO80 complex subunit B	R	protein	356	Homo sapiens	Q9C086
Actin-related protein 5	H	protein	607	Homo sapiens	Q9H9F9
INO80 complex subunit C	Q	protein	192	Homo sapiens	Q6PI98
Histone H3.1	I, M	protein	136	Homo sapiens	P68431
Histone H2A type 1-B/E	K, O	protein	130	Homo sapiens	P04908
Histone H2B type 1-J	L, P	protein	126	Homo sapiens	P06899
DNA (158-mer)	X	DNA	158	synthetic construct
DNA (158-mer)	Y	DNA	158	synthetic construct

Sequence of entity 1 (A, C, E), FASTA

>7ZI4_1 RuvB-like 1 (chains A, C, E)
MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK
MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI
GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL
QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL
HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF
VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI
IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN
GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK

Sequence of entity 2 (B, D, F), FASTA

>7ZI4_2 RuvB-like 2 (chains B, D, F)
MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVL
EMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALT
QAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIE
SLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVH
TVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDE
VHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTT
PYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTE
VQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS

Sequence of entity 3 (G), FASTA

>7ZI4_3 Chromatin-remodeling ATPase INO80 (chains G)
MASELGARDDGGCTELAKPLYLQYLERALRLDHFLRQTSAIFNRNISSDDSEDGLDDSNP
LLPQSGDPLIQVKEEPPNSLLGETSGAGSSGMLNTYSLNGVLQSESKCDKGNLYNFSKLK
KSRKWLKSILLSDESSEADSQSEDDDEEELNLSREELHNMLRLHKYKKLHQNKYSKDKEL
QQYQYYSAGLLSTYDPFYEQQRHLLGPKKKKFKEEKKLKAKLKKVKKKRRRDEELSSEES
PRRHHHQTKVFAKFSHDAPPPGTKKKHLSIEQLNARRRKVWLSIVKKELPKANKQKASAR
NLFLTNSRKLAHQCMKEVRRAALQAQKNCKETLPRARRLTKEMLLYWKKYEKVEKEHRKR
AEKEALEQRKLDEEMREAKRQQRKLNFLITQTELYAHFMSRKRDMGHDGIQEEILRKLED
SSTQRQIDIGGGVVVNITQEDYDSNHFKAQALKNAENAYHIHQARTRSFDEDAKESRAAA
LRAANKSGTGFGESYSLANPSIRAGEDIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGI
LADEMGLGKTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWG
NPHDRKVIRRFWSQKTLYTQDAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSS
SSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESH
AENKSAIDENQLSRLHMILKPFMLRRIKKDVENELSDKIEILMYCQLTSRQKLLYQALKN
KISIEDLLQSSMGSTQQAQNTTSSLMNLVMQFRKVCNHPELFERQETWSPFHISLKPYHI
SKFIYRHGQIRVFNHSRDRWLRVLSPFAPDYIQRSLFHRKGINEESCFSFLRFIDISPAE
MANLMLQGLLARWLALFLSLKASYRLHQLRSWGAPEGESHQRYLRNKDFLLGVNFPLSFP
NLCSCPLLKSLVFSSHCKAVSGYSDQVVHQRRSATSSLRRCLLTELPSFLCVASPRVTAV
PLDSYCNDRSAEYERRVLKEGGSLAAKQCLLNGAPELAADWLNRRSQFFPEPAGGLWSIR
PQNGWSFIRIPGKESLITDSGKLYALDVLLTRLKSQGHRVLIYSQMTRMIDLLEEYMVYR
KHTYMRLDGSSKISERRDMVADFQNRNDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNP
TVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMVISGGNFKPDTLK
PKEVVSLLLDDEELEKKLRLRQEEKRQQEETNRVKERKRKREKYAEKKKKEDELDGKRRK
EGVNLVIPFVPSADNSNLSADGDDSFISVDSAMPSPFSEISISSELHTGSIPLDESSSDM
LVIVDDPASSAPQSRATNSPASITGSVSDTVNGISIQEMPAAGRGHSARSRGRPKGSGST
AKGAGKGRSRKSTAGSAAAMAGAKAGAAAASAAAYAAYGYNVSKGISASSPLQTSLVRPA
GLADFGPSSASSPLSSPLSKGNNVPGNPKNLHMTSSLAPDSLVRKQGKGTNPSGGR

Sequence of entity 4 (J, N), FASTA

>7ZI4_4 Histone H4 (chains J, N)
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLK
VFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG

Sequence of entity 5 (R), FASTA

>7ZI4_5 INO80 complex subunit B (chains R)
MSKLWRRGSTSGAMEAPEPGEALELSLAGAHGHGVHKKKHKKHKKKHKKKHHQEEDAGPT
QPSPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYR
AWLDEDSNLSPSPLRDLSGGLGGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQ
RALLQKARSQPSPMLPLPVAEGCPPPALTEEMLLKREERARKRRLQAARRAEEHKNQTIE
RLTKTAATSGRGGRGGARGERRGGRAAAPAPMVRYCSGAQGSTLSFPPGVPAPTAVSQRP
SPSGPPPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQMRLGGPEGPGSPLLAT

Sequence of entity 6 (H), FASTA

>7ZI4_6 Actin-related protein 5 (chains H)
MAANVFPFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPEPRLQ
FRAVCARGRGGARGASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHL
GVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSM
CSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLS
RMEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFSSKLLGSTLTSEEKQERRQQ
QLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSY
IQKLSIAVEQAKQKILQAEVNLEVDVVDSKPETPDLEQLEPSLEDVESMNDFDPLFSEET
PGVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYILDRYP
KDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNPVLDAWYGARDW
ALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQASRSSDAQASSKGSAAGG
GGAGEQA

Sequence of entity 7 (Q), FASTA

>7ZI4_7 INO80 complex subunit C (chains Q)
MAAQIPIVATTSTPGIVRNSKKRPASPSHNGSSGGGYGASKKKKASASSFAQGISMEAMS
ENKMVPSEFSTGPVEKAAKPLPFKDPNFVHSGHGGAVAGKKNRTWKNLKQILASERALPW
QLNDPNYFSIDAPPSFKPAKKYSDVSGLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTG
YLALRKATSIVP

Sequence of entity 8 (I, M), FASTA

>7ZI4_8 Histone H3.1 (chains I, M)
MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE
LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI
MPKDIQLARRIRGERA

Sequence of entity 9 (K, O), FASTA

>7ZI4_9 Histone H2A type 1-B/E (chains K, O)
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK
TESHHKAKGK

Sequence of entity 10 (L, P), FASTA

>7ZI4_10 Histone H2B type 1-J (chains L, P)
MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT
KYTSAK

Sequence of entity 11 (X), FASTA

>7ZI4_11 DNA (158-MER) (chains X)
CCGGTGCCGAGGCCGCTCAATTGGTCGTAGACAGCTCTAGCACCGCTTAAACGCACGTAC
GCGCTGTCCCCCGCGTTTTAACCGCCAAGGGGATTACTCCCTAGTCTCCAGGCACGTGTC
AGATATATACATCCTGTGCATGTACTCGGGATATTGAT

Sequence of entity 12 (Y), FASTA

>7ZI4_12 DNA (158-MER) (chains Y)
ATCAATATCCCGAGTACATGCACAGGATGTATATATCTGACACGTGCCTGGAGACTAGGG
AGTAATCCCCTTGGCGGTTAAAACGCGGGGGACAGCGCGTACGTGCGTTTAAGCGGTGCT
AGAGCTGTCTACGACCAATTGAGCGGCCTCGGCACCGG

Ligands and cofactors

ID	Name	Formula	Copies
ADP	Adenosine-5'-diphosphate	C10 H15 N5 O10 P2	8
BEF	Beryllium trifluoride ion	Be F3	1
ZN	Zinc ion	Zn	1

Primary citation

Cryo-EM structure of the human INO80 complex bound to a WT nucleosome. Vance, N.R., Ayala, R., Willhoft, O. et al. To be published.

Other PDB entries of the same protein (UniProt Q9Y265 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2C9O 2.2 Å, 3D Structure of the human RuvB-like helicase RuvBL1
8QR1 2.4 Å, Cryo-EM structure of the human Tip60 complex
9EMA 2.4 Å, RUVBL1/2 in complex with ATP and CB-6644 inhibitor
6K0R 2.5 Å, Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin
9C57 2.75 Å, Reconstituted P400 Subcomplex of the human TIP60 complex
2XSZ 3.0 Å, The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II
9CAE 3.07 Å, Cryo-EM structure of the reconstituted RuvBL lobe of the human TIP60 complex (composite…
8X15 3.2 Å, Structure of nucleosome-bound SRCAP-C in the apo state
8X19 3.2 Å, Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
8X1C 3.2 Å, Structure of nucleosome-bound SRCAP-C in the ADP-bound state
8XVT 3.2 Å, The core subcomplex of human NuA4/TIP60 complex
9SN2 3.2 Å, Cryo-EM reconstruction of the RUVBL1-RUVBL2-CCDC103 (R2C) complex

Browse structure collections

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