8ANK: Amyloid-forming peptide pEFIAWL from human GLP-1
Structure of the amyloid-forming peptide pEFIAWL from human GLP-1. Determined by X-ray diffraction at 1.3 Å resolution. Released 2 Aug 2023.
- Method
- X-ray diffraction
- Resolution
- 1.3 Å
- Organism
- synthetic construct
- Chains
- 1
- Atoms
- 57
- Mol. weight
- 0.76 kDa
- Released
- 2 Aug 2023
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RCSB PDB
PDBe
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Peptide pEFIAWL from hGLP-1 | A | protein | 6 | synthetic construct | P01275 (AlphaFold model) |
Sequence of entity 1 (A), FASTA
>8ANK_1 Peptide pEFIAWL from hGLP-1 (chains A)
QFIAWL
Primary citation
Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Horvath, D., Durvanger, Z., K Menyhard, D. et al. Nat Commun (2023) 14:4621-4621. DOI 10.1038/s41467-023-40294-x · PubMed
Other PDB entries of the same protein (UniProt P01275 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 6PHI 1.1 Å, Crystal structure of native glucagon in space group I41 at 1.1 A resolution
- 6PHK 1.18 Å, Crystal structure of glucagon analog with mono-stereoinversion at position 21 (D-Asp21)…
- 6PHO 1.42 Å, Crystal structure of glucagon analog with selenomethionine substitutions at position 1…
- 6PHL 1.44 Å, Crystal structure of glucagon analog with mono-stereoinversion at position 23 (D-Val23)…
- 8ANJ 1.55 Å, Structure of the amyloid-forming peptide DFINWL from human GLP-2
- 6PHP 1.65 Å, Crystal structure of glucagon analog with 4-bromo-phenylalanine substitutions at…
- 4ZGM 1.8 Å, Crystal structure of Semaglutide peptide backbone in complex with the GLP-1 receptor…
- 5OTU 1.8 Å, Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Hcs
- 6PHJ 1.99 Å, Crystal structure of native glucagon in space group P213 at 1.99 A resolution
- 5OTV 2.0 Å, Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cyc/Thr11Hcs
- 5OTX 2.0 Å, Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cys/Thr11Cys
- 3IOL 2.1 Å, Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of…
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