8GHN: Protein HIR1

Name: PDB 8GHN: Composite model of the yeast Hir Complex with Asf1/H3/H4
Published: 2024-07-17
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: chaperone

Composite model of the yeast Hir Complex with Asf1/H3/H4. Determined by electron microscopy at 2.96 Å resolution. Released 17 Jul 2024.

Method: Electron microscopy
Resolution: 2.96 Å
Organism: Saccharomyces cerevisiae
Chains: 15
Atoms: 59,784
Mol. weight: 1295.94 kDa
Released: 17 Jul 2024

Explore 8GHN in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8GHN contains 333 α-helices and 343 β-strands across 15 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 19 helices, 60 β-strands

Element	Residues	Length	Sheet
β-strand	2-4	3	1
β-strand	10	1	2
β-strand	12-13	2	3
β-strand	16-17	2	3
β-strand	20-25	6	4
β-strand	31-36	6	4
β-strand	41-45	5	4
α-helix	46-58	13
α-helix	63-65	3
α-helix	66-68	3
β-strand	73-75	3	4
β-strand	82-87	6	5
β-strand	94-98	5	5
α-helix	102	1
β-strand	103-109	7	5
α-helix	115-117	3
β-strand	126-133	8	5
β-strand	140-145	6	6
β-strand	151-156	6	6
β-strand	161-165	5	6
β-strand	171-175	5	6
β-strand	182-187	6	7
β-strand	193-198	6	7
β-strand	203-209	7	7
β-strand	215-222	8	7
α-helix	224-226	3
β-strand	237	1	8
β-strand	239-240	2	9
β-strand	246-253	8	9
β-strand	258-264	7	9
β-strand	273-275	3	9
β-strand	281-291	11	8
β-strand	325-332	8	8
β-strand	337-341	5	8
β-strand	349-352	4	8
β-strand	359-364	6	1
β-strand	370-375	6	1
β-strand	379	1	2
β-strand	380-384	5	1
α-helix	385-386	2
α-helix	392	1
β-strand	393	1	8
α-helix	394-395	2
α-helix	396-401	6
α-helix	404-406	3
α-helix	413-416	4
α-helix	419-435	17
β-strand	488-490	3	10
β-strand	493-496	4	10
β-strand	499	1	11
α-helix	545-550	6
β-strand	551	1	12
α-helix	557-559	3
β-strand	563	1	13
β-strand	565-567	3	14
β-strand	621	1	15
α-helix	627-631	5
β-strand	640	1	16
β-strand	652-657	6	17
β-strand	662-668	7	17
α-helix	673-675	3
α-helix	679-684	6
β-strand	687-692	6	17
β-strand	697-703	7	17
β-strand	707-712	6	18
β-strand	718-723	6	18
β-strand	727-732	6	18
β-strand	737	1	18
β-strand	742-743	2	18
β-strand	748-754	7	19
β-strand	757-762	6	19
β-strand	766-771	6	19
β-strand	776-783	8	19
α-helix	785-788	4
β-strand	793	1	20
β-strand	803-810	8	16
β-strand	815-821	7	16
β-strand	825-829	5	16
β-strand	836-838	3	16

Chain B: 25 helices, 60 β-strands

Element	Residues	Length	Sheet
β-strand	2-7	6	21
β-strand	17-21	5	22
β-strand	24-28	5	22
β-strand	33-38	6	22
α-helix	39-46	8
β-strand	59-62	4	22
β-strand	71-76	6	23
β-strand	80-85	6	23
β-strand	88-93	6	23
β-strand	96	1	24
β-strand	103	1	24
α-helix	104-105	2
β-strand	110-116	7	23
β-strand	122-129	8	25
β-strand	134-140	7	25
β-strand	144-149	6	25
β-strand	155-160	6	25
β-strand	167-172	6	26
β-strand	178-183	6	26
β-strand	187-192	6	26
β-strand	201-206	6	26
β-strand	209	1	27
β-strand	217	1	28
β-strand	226-230	5	29
β-strand	232	1	27
α-helix	237	1
β-strand	243-248	6	29
β-strand	255-260	6	29
α-helix	266	1
β-strand	267-272	6	28
β-strand	276-281	6	30
β-strand	286-290	5	30
β-strand	292-297	6	28
β-strand	303-307	5	28
β-strand	313-318	6	28
β-strand	325-330	6	21
β-strand	336-341	6	21
β-strand	345-350	6	21
α-helix	353-356	4
β-strand	358-360	3	30
α-helix	361	1
α-helix	362-370	9
α-helix	373-378	6
β-strand	441-442	2	31
α-helix	443-445	3
β-strand	486	1	20
α-helix	488-491	4
β-strand	493	1	32
β-strand	495-497	3	14
β-strand	499-500	2	31
α-helix	501-503	3
β-strand	505-508	4	33
β-strand	516-521	6	33
α-helix	530	1
β-strand	531-539	9	33
β-strand	542-551	10	33
β-strand	555-560	6	16
β-strand	565-569	5	16
β-strand	573-577	5	16
β-strand	583	1	16
α-helix	586-587	2
β-strand	588-589	2	16
β-strand	594-600	7	34
β-strand	603-608	6	34
β-strand	612-617	6	34
β-strand	622-623	2	34
β-strand	628-629	2	34
α-helix	631-634	4
β-strand	646-647	2	14
α-helix	649-650	2
β-strand	651-656	6	13
β-strand	657	1	12
β-strand	662-666	5	13
β-strand	671-675	5	13
β-strand	680-685	6	13
α-helix	689-692	4
α-helix	711-714	4
α-helix	719-729	11
α-helix	735-750	16
α-helix	753-764	12
α-helix	772-790	19
α-helix	794-811	18
α-helix	814-825	12
α-helix	841-854	14
α-helix	861-870	10

Chain C: 16 helices, 22 β-strands

Element	Residues	Length	Sheet
β-strand	491	1	32
β-strand	495-496	2	35
α-helix	500-502	3
β-strand	505-508	4	36
β-strand	516-521	6	36
β-strand	531-537	7	36
α-helix	539-541	3
β-strand	544-551	8	36
β-strand	555-560	6	13
β-strand	565-569	5	13
β-strand	573-577	5	13
β-strand	583	1	13
α-helix	586-587	2
β-strand	588-589	2	13
β-strand	594-600	7	37
β-strand	603-608	6	37
β-strand	612-617	6	37
β-strand	622-623	2	37
β-strand	628-629	2	37
α-helix	631-633	3
α-helix	635	1
β-strand	643	1	15
β-strand	646-647	2	35
β-strand	653-656	4	18
β-strand	662-665	4	18
β-strand	671-675	5	18
β-strand	680-685	6	18
α-helix	689-692	4
α-helix	702-704	3
α-helix	735-744	10
α-helix	749-764	16
α-helix	772-790	19
α-helix	794-811	18
α-helix	814-825	12
α-helix	835-837	3
α-helix	840-853	14
α-helix	854-856	3
α-helix	861-870	10

Chain D: 88 helices, 14 β-strands

Element	Residues	Length	Sheet
α-helix	13-42	30
α-helix	46-57	12
α-helix	75-99	25
α-helix	107-125	19
α-helix	127-129	3
α-helix	130-142	13
α-helix	146-157	12
α-helix	163-167	5
α-helix	176-191	16
α-helix	201-205	5
α-helix	208-210	3
α-helix	218-220	3
α-helix	223-239	17
β-strand	244-249	6	38
α-helix	254-264	11
α-helix	270-275	6
α-helix	280-283	4
β-strand	290-295	6	38
α-helix	377-393	17
α-helix	402-410	9
α-helix	421-432	12
α-helix	436-442	7
α-helix	454-458	5
β-strand	482	1	39
α-helix	488-498	11
α-helix	502-513	12
β-strand	516-518	3	40
β-strand	523-524	2	40
α-helix	525-528	4
β-strand	530	1	39
α-helix	533-556	24
α-helix	562-586	25
α-helix	594-617	24
α-helix	623-640	18
α-helix	647-661	15
β-strand	668	1	41
α-helix	677-678	2
β-strand	679	1	41
α-helix	681-697	17
α-helix	698-700	3
α-helix	709-715	7
α-helix	716-720	5
α-helix	721-727	7
α-helix	738-739	2
α-helix	740-744	5
α-helix	749-763	15
α-helix	769-787	19
α-helix	790-793	4
α-helix	797-824	28
α-helix	836-861	26
α-helix	868-871	4
α-helix	873-900	28
α-helix	903-924	22
α-helix	929-932	4
α-helix	933-942	10
α-helix	948-960	13
α-helix	985-999	15
α-helix	1015-1025	11
α-helix	1028-1029	2
α-helix	1034-1048	15
α-helix	1053-1060	8
α-helix	1076-1080	5
α-helix	1083-1100	18
α-helix	1106-1108	3
α-helix	1109-1120	12
α-helix	1127-1147	21
α-helix	1149-1153	5
α-helix	1155-1181	27
α-helix	1187-1208	22
α-helix	1215-1217	3
β-strand	1218-1219	2	42
β-strand	1225-1229	5	43
α-helix	1230	1
β-strand	1235-1239	5	43
α-helix	1240-1242	3
β-strand	1243-1244	2	42
α-helix	1248-1272	25
α-helix	1281-1290	10
α-helix	1299-1302	4
α-helix	1306-1315	10
α-helix	1324-1339	16
α-helix	1345-1354	10
α-helix	1356-1359	4
α-helix	1374-1394	21
α-helix	1402-1410	9
α-helix	1411-1415	5
α-helix	1419-1429	11
β-strand	1430	1	44
β-strand	1440	1	44
α-helix	1456-1471	16
α-helix	1475-1485	11
α-helix	1494-1512	19
α-helix	1520-1524	5
α-helix	1525-1527	3
α-helix	1530-1543	14
α-helix	1546-1548	3
α-helix	1551-1566	16
α-helix	1570-1572	3
α-helix	1573-1580	8
α-helix	1581-1585	5
α-helix	1586-1591	6
α-helix	1634-1647	14

Chains E and K: 9 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	425-427	3
α-helix	429-432	4
α-helix	434-437	4
β-strand	438-443	6	21
α-helix	450	1
β-strand	451-455	5	21
β-strand	459	1	45
α-helix	465	1
β-strand	466	1	45
α-helix	467	1
β-strand	474-476	3	28
α-helix	477-485	9
α-helix	492-507	16
α-helix	578-589	12
β-strand	595-597	3	29

Chain F: 3 helices, 3 β-strands

Element	Residues	Length	Sheet
β-strand	453-455	3	1
α-helix	457-460	4
α-helix	464-466	3
β-strand	473-476	4	8
α-helix	477-485	9
β-strand	595-597	3	9

Chain G: 21 helices, 57 β-strands

Element	Residues	Length	Sheet
β-strand	2-4	3	46
β-strand	10	1	47
β-strand	12-13	2	48
β-strand	16-17	2	48
β-strand	20-25	6	49
β-strand	31-36	6	49
β-strand	41-45	5	49
α-helix	46-58	13
α-helix	63-65	3
α-helix	66-68	3
β-strand	73-75	3	49
β-strand	82-87	6	50
β-strand	94-98	5	50
α-helix	102	1
β-strand	103-109	7	50
α-helix	115-117	3
β-strand	126-133	8	50
β-strand	140-145	6	51
β-strand	151-156	6	51
β-strand	160-165	6	51
β-strand	171-176	6	51
β-strand	182-187	6	52
β-strand	193-198	6	52
β-strand	203-209	7	52
β-strand	215-222	8	52
α-helix	224-226	3
β-strand	237	1	53
β-strand	239-240	2	54
β-strand	246-253	8	54
β-strand	258-264	7	54
β-strand	272-275	4	54
β-strand	281-291	11	53
β-strand	325-332	8	53
β-strand	337-341	5	53
β-strand	349-352	4	53
β-strand	359-364	6	46
β-strand	370-375	6	46
β-strand	379	1	47
β-strand	380-384	5	46
α-helix	385-386	2
α-helix	392	1
β-strand	393	1	53
α-helix	394-395	2
α-helix	396-401	6
α-helix	404-406	3
α-helix	413-415	3
α-helix	419-435	17
α-helix	545-550	6
β-strand	551	1	55
α-helix	557-559	3
β-strand	563	1	56
β-strand	565-567	3	57
β-strand	621	1	58
α-helix	627-631	5
β-strand	640	1	59
α-helix	645-647	3
β-strand	651-657	7	60
β-strand	662-668	7	60
α-helix	673-675	3
α-helix	679-684	6
α-helix	686	1
β-strand	687-692	6	60
β-strand	697-703	7	60
β-strand	707-712	6	61
β-strand	718-723	6	61
β-strand	727-732	6	61
β-strand	737	1	61
β-strand	742-743	2	61
β-strand	748-754	7	62
β-strand	757-762	6	62
β-strand	767-771	5	62
β-strand	776-780	5	62
α-helix	785-788	4
β-strand	804-810	7	59
β-strand	815-820	6	59
β-strand	825	1	59
β-strand	827-830	4	59
β-strand	835-838	4	59

Chain H: 26 helices, 61 β-strands

Element	Residues	Length	Sheet
β-strand	2-7	6	63
β-strand	17-21	5	64
β-strand	24-28	5	64
β-strand	33-38	6	64
α-helix	39-46	8
β-strand	59-62	4	64
β-strand	71-76	6	65
β-strand	80-85	6	65
β-strand	88-93	6	65
β-strand	96	1	66
β-strand	103	1	66
α-helix	104-105	2
β-strand	110-116	7	65
β-strand	122-129	8	67
β-strand	134-140	7	67
β-strand	144-149	6	67
β-strand	155-160	6	67
β-strand	167-172	6	68
β-strand	178-183	6	68
β-strand	187-192	6	68
β-strand	201-206	6	68
β-strand	209	1	69
β-strand	217	1	70
β-strand	226-230	5	71
β-strand	232	1	69
α-helix	237	1
β-strand	243-248	6	71
β-strand	255-260	6	71
α-helix	266	1
β-strand	267-272	6	70
β-strand	276-281	6	72
β-strand	286-290	5	72
β-strand	292-297	6	70
β-strand	303-307	5	70
β-strand	313-318	6	70
β-strand	325-330	6	63
β-strand	336-341	6	63
β-strand	345-350	6	63
α-helix	353-356	4
β-strand	358-360	3	72
α-helix	361	1
α-helix	362-370	9
α-helix	373-378	6
β-strand	441-442	2	73
α-helix	443-445	3
β-strand	481	1	74
α-helix	488-491	4
β-strand	493	1	75
β-strand	495-497	3	57
β-strand	499-500	2	73
α-helix	501	1
β-strand	502	1	74
α-helix	503	1
β-strand	505-508	4	76
β-strand	516-521	6	76
α-helix	530	1
β-strand	531-539	9	76
β-strand	542-551	10	76
β-strand	555-560	6	59
β-strand	565-569	5	59
β-strand	573-577	5	59
β-strand	583	1	59
α-helix	586-587	2
β-strand	588-589	2	59
β-strand	594-600	7	77
β-strand	603-608	6	77
β-strand	612-617	6	77
β-strand	622-623	2	77
β-strand	628-629	2	77
β-strand	646-647	2	57
β-strand	651-656	6	56
β-strand	657	1	55
β-strand	662-666	5	56
β-strand	671-674	4	56
β-strand	681-685	5	56
α-helix	689-692	4
α-helix	711-714	4
α-helix	719-729	11
α-helix	735-750	16
α-helix	753-764	12
α-helix	772-790	19
α-helix	794-811	18
α-helix	814-825	12
α-helix	829	1
α-helix	841-854	14
α-helix	858-860	3
α-helix	861-871	11

6 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Protein HIR1	A, G	protein	840	Saccharomyces cerevisiae	P32479 (AlphaFold model)
Protein HIR2	B, C, H, I	protein	875	Saccharomyces cerevisiae	P32480 (AlphaFold model)
Histone transcription regulator 3	D, J	protein	1648	Saccharomyces cerevisiae	P47171 (AlphaFold model)
Histone promoter control protein 2	E, F, K, L	protein	625	Saccharomyces cerevisiae	Q01448 (AlphaFold model)
Histone H3	M	protein	136	Saccharomyces cerevisiae	P61830
Histone H4	N	protein	103	Saccharomyces cerevisiae	P02309
Histone chaperone	O	protein	279	Saccharomyces cerevisiae	P32447

Sequence of entity 1 (A, G), FASTA

>8GHN_1 Protein HIR1 (chains A, G)
MKVVKFPWLAHREESRKYEIYTVDVSHDGKRLATGGLDGKIRIWSIDSILRCMELESLTP
EIPLPQDLQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGS
EHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRSVIVWNGSTFEKLKRFDVHQS
LVKGVVFDPANKYFATTSDDRTMKIFRYHKTGDISFTIEHIITEPFKESPLTTYFRRPSW
SPDGQHIAVPNATNGPVSSVAIVNRGTWDTNVSLIGHDAPTEVARFNPRLFERNAGVKQK
KDDDPENALVGQNDDKVHHFDKNIDSVVATAGQDKSLAVWSTSRPRPILVAFDIANKSIT
DMSWNPDGSLLFVASLDSSITLFKFENNELGKPIPLEKNMEQLYRYGVDKDSLDFPESIN
QLLLEDQTKSFKHTKISTSKLGENHPTLATNSASNQKDNNDASVSRSEHINILIPKRKKD
AILNKAVTLKSGKKRVAPTLISTSSSSPFSNGIKKPTLDSKRIENNVKSSTKTINSKNTL
LNVPEGVEKKISISSFPLPRLGIHSLIMGTKERSAWKISNSELENDDADNAGGKGSDGTS
NSIDDIAVLSEEENDFHRMTLNAKLTQEKIWSEEPTTRCLLQSDVIPDTDVVVLEGGSLD
DIAVLEIRNGVERSIQFDSEALLDNPTRILGYQGGKRTIETFIPEVIICAIGSKDCKCWC
LASANGSIYILSYNGQQRIPKICLGHKVIKMVTSSKYLLVLTERGLFFAWDLLDLKLVLR
NVPILPILNGQPIHGNKVRINKVIKCFRLDGSSCDLLLEVGDPKNVYKWTKDLGCWSLYK

Sequence of entity 2 (B, C, H, I), FASTA

>8GHN_2 Protein HIR2 (chains B, C, H, I)
MRLLKYPLDIHNEQVNALAALGPYIILAGSGGHVMAWRQQQLVDTAFDRVMIKDLKPEVS
FQVDQDTTGDIFFITGDLETLYIGSEHRLWGYSGWLCRDTNNINSVEKMNSKLLFECKSP
STITDVKYDINLGILFVLLSNENKILLFRHKTFDKLSEITIDKASKPITGIIDPTGQTFT
VMTSDRSILVYQINKTGTHKLINKLTQHVQMYPLHYRISMSPQADILPVINSVKGVPNNA
TSCTALLDRNNNYKVTKTLVTPSSNGCRVLVYSPAFYEKPNLKKGTSTRYNLIATSGSTD
GTILVWNTKRMKPLFNALQVSSTAINDMSWSQDGFTLFAISNDATLYTFAFQEKDLGVAL
PQTEIKSLQEVNKKLPKLEEPLAEQIPKSFPENIKLEESASAAPIPNDIGRSAVGKKPTK
KKTANNQTNGIKTIQSTSMEFNTPSYTVPRDLKRKPKEATPSNIAPGSKKQKKELQPIDF
LDTGLLLPNTSFSRIRLATPKIRSTFKYSPINNPNLILDVKNGSGNEQRPTIVKLTSKVL
DQDQVLFQDFIPKLITICTAGDTFWSFCSEDGSIYIYSDSGRKLMAPLVLGVSISFLEAC
GTYLLCLTSIGELYCWNIEQKKLAFPTNTIYPLLNPSLRYSDDILTRAENITLCSITKKG
VPLVTLSNGDGYLFDKNMETWLLVSDGWWAYGSQYWDTTNTTGLSSSKANTDSFNGSESN
INEIVSDIKNDNQSIINFLECKTNDELNRKGRIKNLQRFARTILMKEGFENMEEIVTLSH
LENKILISIRLEEPEEFSKLMMVYCIRLSELGYMDRLNDVFQWLYDDLPISGTGSAFADK
DFKRNLLKKILIACGDIRQVQRVTTRYAKEMNIIS

Sequence of entity 3 (D, J), FASTA

>8GHN_3 Histone transcription regulator 3 (chains D, J)
MSMFNALNSNIEGEQYEAEEHSRELQIEQSFNILQDALIDLKNKDFEKSDSKFQELFQID
VVKPDRWGMYRNSSPTLDNLRYLCYRNRGMYYHLYLENNYERLNSQELVNCILKAVENLV
ESIQHSDADFAVTDLLARIFKSFNSVKLERLISEYEFTKQENLSLLLGRHRKFLLNDLTL
MMNNYVELTNKLLVPNLSDNTIFERYHLEKYKDIKPEPLAFGPILSRISEMKKQDEEIMK
KLDVFNVTLNEESWDEVAKALKNLLPSVKTSSLIGRNMDPYNEIEEPIEAVKFELSEAIN
NTPSLDRESERQEEEQDNESVRADDKSGNLAPSDIQTNEEARPNKRTDEHIDSTKPLQRS
SKRFKEREQENSKELVMDVHKRFFGEFNTLLSYIHILPFCDFDTFASKFIIGSSDKQPEK
FIPYTDLYECLKSWSSRYTDIFNQNDYLSSGSNENEELFQLNALLKSNAFDDKESFPRYL
NDLDSDHIRSFISEVNAGNLHFHQVRLKLLFKLLGTYDEGNGRRLIIDYLWESQLLKIVL
WFVFGIESNIFALINKNKRQCKYLALSIYELLVNHLGNIVEEITNKRIQGHKSADLKSQR
NKVEKRIRSWHTLLEQIADEKDKELYVHFQWTHYCFLQYTCDIVDSRLSETLTSLENTIK
DSDSSLDIAYPNYRHIPALNLNTVQSQKRKIRIIQNITVEDISEDTNSDTHSENHLETLE
KVLLHILHPSTNHSNIDEEMVSFIFNSPFLLKIRLWGVLFSSYVKKSSIQDVQRIYFHVL
DFMKGALTSPVYKESNPHGRHQMLLTVLTAIGYLSSQLTAILNSNRWESSDFVLEDYMFE
KLLQTFFFFYTVLFYESSAVNDVSNKSFFKRASKSSGKMKDIMIDLATLILYYYDLQAKL
RTPAEQGIETTELIWSLHTLFGHFHFCDASNGKFLDLAEKLLCQFINNDSFLQLKQILWC
RYHYAIASDNFSPDLHDTKAVEMEKIHSLPLGTYLIKLQYQNKNPYLSSSKTTLKQIMDN
IIEKIGDPSTLDNHIISRNSFLLNEYLSRPITADLLKHTFSGATSLYLTSPNDELQQGMT
AGLFYVSSLQSLGLYKMRKKSMQARPSELDSIIRMLKNDIIYNTNRFESWILLGKCYSYI
VEDDLIWTSDKITVPEKKDVIALTQRKAILCYLMAISIYYSKLDRTIDDKKIILEALDDL
GSMLISGYYNPMNKLCFSWKSSAENTMRLSETGEVVMEKTKKITTISDFNIEQSIFLCFN
RACSLSGDIKSQDDVFVLNWSSFYNLAKFFFKTDGGNNCKLVAKYITQGCQIAYESSPAK
DPIIEPHYLLVNACYKWVKRGVIGVNEALTLLSKDNQFFQEQEEFWVNDEGLAWDYQEKF
FFDKIIRLLRHLLSVDKKKWQHRPRYRIARILFDDLGDVNGALEEMDSLISAKSINKNLV
NIWKPDFERPGKHFIYTYQYLVLYLDLLFAIKDFNTTGLVIKKLRRFGSGTVNVNELLER
AINVYTQSAKIKLQLQDKSYVEQILPTLNYQEFLKISEQLNQVFDQGKYPEEISSGLKLA
FQLKKGHSGIAFDSVCLGIYFEYLYFPLARQDQSLTDVNDENNPALPSSGSVTSKSTPDP
TSKPSAIKKRVTKKEVFDRVRLLVDKIT

Sequence of entity 4 (E, F, K, L), FASTA

>8GHN_4 Histone promoter control protein 2 (chains E, F, K, L)
MDQKAIVLDNSKSGSKQTKSSGKMQTQTDTNAEVLNTDNSIKKETGSDSEDLFNKFSNKK
TNRKIPNIAEELAKNRNYVKGASPSPIIISGSSSTSPSGPSSSSTNPMGIPTNRFNKNTV
ELYQHSPSPVMTTNKTDTEEKRQNNRNMDNKNTPERGSSSFAAKQLKISSLLTISSNEDS
KTLHINDTNGNKNSNAASNNIPSAYAELHTEGNSIESLIKPPSSPRNKSLTPKVILPTQN
MDGTIAKDPHLGDNTPGILIAKTSSPVNLDVESTAQSLGKFNKSTNSLKAALTKAPAEKV
SLKRSISSVTNSDSNISSSKKPTSEKAKKSSSASAILPKPTTTKTSKKAASNSSDSTRKK
NASNKTTSAIKKESNAGSKLNTVKKENSSLSSIKATEKEKDKGGNSTEAKNSTSNVRKEP
TAKSPKRLVAAPTVSPPKILQTAETKAKEPSILIDVPLYQADTNDYLDENGQVIFNLSTL
IKEKYHPKSKELAQLKDSKRNLLMQLSDHSNGSLEKEKDEEGDVIELDDDEDMEEDEGEI
DTETNTVTTTISPKKKSHPMKGKNLIGKYDVEDPFIDDSELLWEEQRAATKDGFFVYFGP
LIEKGHYASLERANGTMKRGGVKNK

Sequence of entity 5 (M), FASTA

>8GHN_5 Histone H3 (chains M)
MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTE
LLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTI
QKKDIKLARRLRGERS

Sequence of entity 6 (N), FASTA

>8GHN_6 Histone H4 (chains N)
MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLK
SFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG

Sequence of entity 7 (O), FASTA

>8GHN_7 Histone chaperone (chains O)
MSIVSLLGIKVLNNPAKFTDPYEFEITFECLESLKHDLEWKLTYVGSSRSLDHDQELDSI
LVGPVPVGVNKFVFSADPPSAELIPASELVSVTVILLSCSYDGREFVRVGYYVNNEYDEE
ELRENPPAKVQVDHIVRNILAEKPRVTRFNIVWDNENEGDLYPPEQPGVDDEEEEDDEEE
DDDEDDEDDEDDDQEDGEGEAEEAAEEEEEEEEKTEDNETNLEEEEEDIENSDGDEEEGE
EEVGSVDKNEDGNDKKRRKIEGGSTDIESTPKDAARSTN

Primary citation

Structure of the Hir histone chaperone complex. Kim, H.J., Szurgot, M.R., van Eeuwen, T. et al. Mol Cell (2024) 84:2601-2617.e12. DOI 10.1016/j.molcel.2024.05.031 · PubMed

Other PDB entries of the same protein (UniProt P32479 (AlphaFold model), which also has an AlphaFold model), best resolution first:

8GHL 2.96 Å, the Hir complex core
8GHM 12.0 Å, Hir1 WD40 domains and Asf1/H3/H4

Browse structure collections

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