8UOQ: Composite map of PIC_delta_TFIIK form2

Name: PDB 8UOQ: Composite map of PIC_delta_TFIIK form2
Published: 2024-10-23
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: transcription

Composite map of PIC_delta_TFIIK form2. Determined by electron microscopy at 3.8 Å resolution. Released 23 Oct 2024.

Method: Electron microscopy
Resolution: 3.8 Å
Organism: Saccharomyces cerevisiae
Chains: 30
Atoms: 70,481
Mol. weight: 1336.81 kDa
Ligands: MG, SF4, ZN
Released: 23 Oct 2024

Explore 8UOQ in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8UOQ contains 373 α-helices and 404 β-strands across 28 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 0: 39 helices, 24 β-strands

Element	Residues	Length	Sheet
β-strand	2-4	3	105
β-strand	9-11	3	105
β-strand	17	1	106
α-helix	19-34	16
β-strand	37-41	5	107
α-helix	49-62	14
β-strand	69-72	4	107
α-helix	76-97	22
α-helix	100-102	3
β-strand	105-106	2	107
α-helix	126-137	12
α-helix	140-147	8
α-helix	157-164	8
α-helix	178-187	10
α-helix	192-198	7
β-strand	205-208	4	107
α-helix	211-214	4
α-helix	220-225	6
β-strand	231-233	3	107
α-helix	237-239	3
α-helix	240-246	7
β-strand	251	1	108
α-helix	254-277	24
α-helix	280-291	12
α-helix	295-298	4
α-helix	313-315	3
α-helix	320-322	3
α-helix	328-346	19
β-strand	352-354	3	108
α-helix	356-366	11
α-helix	371-388	18
α-helix	399-409	11
β-strand	416-421	6	108
β-strand	434-439	6	108
α-helix	443-452	10
β-strand	456-460	5	107
α-helix	469-472	4
β-strand	479-482	4	107
β-strand	492-497	6	109
β-strand	499	1	110
β-strand	505	1	110
α-helix	512-514	3
α-helix	516-532	17
β-strand	536-541	6	109
α-helix	544-557	14
α-helix	559-563	5
β-strand	568-571	4	109
α-helix	576-592	17
β-strand	596-601	6	109
α-helix	606-608	3
β-strand	619-623	5	109
α-helix	627-629	3
α-helix	633-646	14
α-helix	650-666	17
β-strand	677-682	6	109
α-helix	685-688	4
α-helix	695-700	6
α-helix	704-706	3
β-strand	708	1	109
α-helix	710-723	14
α-helix	730-732	3
β-strand	739	1	106
α-helix	741-751	11

Chain 1: 28 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	171-176	6
α-helix	178-187	10
α-helix	190-195	6
α-helix	196-202	7
α-helix	206-210	5
α-helix	214-224	11
α-helix	233-236	4
α-helix	246-248	3
α-helix	253-262	10
α-helix	264-271	8
α-helix	280-289	10
α-helix	291-296	6
α-helix	300-302	3
α-helix	311-313	3
α-helix	314-329	16
α-helix	332-334	3
α-helix	340-343	4
β-strand	362	1	111
β-strand	368	1	111
α-helix	371-389	19
α-helix	414-419	6
α-helix	426-429	4
β-strand	432	1	112
α-helix	433	1
β-strand	434	1	113
α-helix	441-444	4
α-helix	466-482	17
α-helix	487-489	3
α-helix	495-514	20
α-helix	544-568	25
α-helix	576-604	29
α-helix	609-638	30

Chain 2: 24 helices, 22 β-strands

Element	Residues	Length	Sheet
α-helix	6-16	11
α-helix	19-25	7
α-helix	29-38	10
α-helix	41-50	10
β-strand	57-58	2	4
α-helix	59-65	7
α-helix	68-70	3
α-helix	71-83	13
β-strand	87	1	5
β-strand	90	1	4
α-helix	92-94	3
β-strand	97-98	2	4
β-strand	100	1	5
α-helix	102-113	12
β-strand	124	1	6
α-helix	131-135	5
α-helix	136-151	16
α-helix	161-169	9
β-strand	174-176	3	7
β-strand	181-183	3	7
α-helix	186-193	8
α-helix	196-210	15
α-helix	218-230	13
β-strand	237	1	6
α-helix	244-255	12
β-strand	259-261	3	8
β-strand	269-271	3	8
α-helix	273-279	7
β-strand	340	1	9
β-strand	346	1	10
β-strand	348	1	9
β-strand	351	1	11
α-helix	354-360	7
β-strand	365-369	5	10
β-strand	373	1	11
β-strand	374-377	4	10
α-helix	380-388	9
α-helix	393-402	10
α-helix	406-422	17
α-helix	435-446	12
β-strand	452-453	2	12
β-strand	458	1	13
α-helix	465-477	13
β-strand	481-485	5	13
β-strand	490-493	4	13
α-helix	498-506	9

Chain 4: 13 helices, 13 β-strands

Element	Residues	Length	Sheet
β-strand	25-31	7	114
α-helix	34-43	10
α-helix	49-67	19
β-strand	72-78	7	114
β-strand	83-87	5	114
α-helix	116-138	23
α-helix	149-165	17
β-strand	174-180	7	114
α-helix	185-186	2
α-helix	190-205	16
β-strand	210-215	6	114
α-helix	222-230	9
β-strand	235-238	4	114
α-helix	244-251	8
α-helix	259-261	3
β-strand	275	1	115
β-strand	282	1	115
β-strand	285	1	116
β-strand	287-289	3	117
β-strand	295-296	2	117
α-helix	299-300	2
α-helix	301-303	3
β-strand	304	1	118
β-strand	311	1	118
α-helix	314-321	8
α-helix	322-325	4

Chain 5: 2 helices, 3 β-strands

Element	Residues	Length	Sheet
β-strand	8-11	4	12
α-helix	14-26	13
β-strand	33-36	4	12
β-strand	39-42	4	12
α-helix	47-61	15

Chain 6: 14 helices, 23 β-strands

Element	Residues	Length	Sheet
α-helix	97-111	15
β-strand	118	1	113
β-strand	120	1	119
β-strand	124-132	9	120
α-helix	134-137	4
α-helix	145-163	19
β-strand	168-175	8	120
β-strand	178-186	9	120
α-helix	189-201	13
α-helix	203-204	2
α-helix	210-220	11
β-strand	229-236	8	120
α-helix	248-256	9
β-strand	259-265	7	120
α-helix	271-280	10
β-strand	288-290	3	120
α-helix	294-305	12
β-strand	309	1	119
β-strand	311	1	112
β-strand	319-320	2	117
β-strand	323	1	116
β-strand	326-328	3	121
β-strand	334-335	2	122
β-strand	342-343	2	122
β-strand	346-348	3	121
β-strand	361-362	2	123
β-strand	369-370	2	123
α-helix	373-377	5
α-helix	380-383	4
β-strand	390-391	2	124
β-strand	402	1	125
β-strand	409	1	125
α-helix	410-411	2
β-strand	427-429	3	124
β-strand	434-436	3	124
α-helix	438-446	9
α-helix	452-456	5

Chain 7: 30 helices, 26 β-strands

Element	Residues	Length	Sheet
α-helix	105-107	3
α-helix	122-124	3
α-helix	125-127	3
β-strand	132	1	126
β-strand	133-134	2	127
β-strand	140-144	5	127
α-helix	150-160	11
β-strand	161-165	5	127
β-strand	170-175	6	127
α-helix	177-186	10
α-helix	190-199	10
β-strand	201	1	126
α-helix	204-206	3
α-helix	207-215	9
β-strand	223-227	5	128
β-strand	232-236	5	128
α-helix	240-245	6
α-helix	323-332	10
β-strand	338	1	128
β-strand	340-341	2	129
α-helix	350-351	2
α-helix	364-372	9
β-strand	379-380	2	129
β-strand	382-385	4	130
α-helix	392-403	12
β-strand	407-410	4	130
α-helix	415-427	13
β-strand	437-438	2	130
β-strand	443-444	2	130
β-strand	452-455	4	130
α-helix	458-461	4
α-helix	468-479	12
α-helix	481	1
β-strand	482-488	7	130
α-helix	490-492	3
α-helix	500-504	5
β-strand	507-509	3	130
β-strand	511-514	4	130
α-helix	523-528	6
β-strand	534-537	4	130
α-helix	540-545	6
β-strand	552-559	8	131
α-helix	560-562	3
α-helix	563-571	9
α-helix	577-582	6
α-helix	585-600	16
β-strand	605-608	4	131
α-helix	612-622	11
α-helix	633-645	13
β-strand	652-654	3	131
β-strand	669-672	4	131
α-helix	680-691	12
β-strand	703-710	8	131
α-helix	715-729	15
β-strand	733-736	4	131
α-helix	753-766	14

Chain A: 66 helices, 71 β-strands

Element	Residues	Length	Sheet
β-strand	11	1	14
β-strand	17-18	2	15
α-helix	24-30	7
β-strand	34	1	16
α-helix	67-69	3
β-strand	83-84	2	16
β-strand	90	1	17
α-helix	96-105	10
β-strand	107	1	18
β-strand	112	1	18
α-helix	120-127	8
α-helix	133-141	9
β-strand	147	1	19
α-helix	169	1
β-strand	170	1	19
α-helix	171-172	2
β-strand	173-177	5	20
β-strand	180-185	6	20
β-strand	198-201	4	20
α-helix	204-212	9
α-helix	216-221	6
α-helix	231-234	4
β-strand	236	1	17
β-strand	239-240	2	16
α-helix	261-281	21
α-helix	288-304	17
α-helix	321-322	2
α-helix	325-328	4
β-strand	344	1	21
β-strand	348-350	3	22
β-strand	352	1	23
β-strand	355-356	2	24
β-strand	365-367	3	25
α-helix	368-373	6
β-strand	376-377	2	2
α-helix	385-393	9
β-strand	402-406	5	2
β-strand	413-414	2	2
α-helix	421-423	3
β-strand	431-434	4	2
β-strand	442-445	4	22
α-helix	449	1
β-strand	457-458	2	22
β-strand	461-463	3	25
β-strand	469	1	25
β-strand	470-471	2	24
α-helix	475-478	4
β-strand	486	1	23
β-strand	488-490	3	22
α-helix	495-504	10
β-strand	506	1	22
α-helix	507-509	3
β-strand	512-513	2	26
β-strand	518-519	2	26
α-helix	525-534	10
β-strand	541	1	27
α-helix	543-552	10
α-helix	560-563	4
β-strand	565	1	28
β-strand	571	1	28
β-strand	572	1	27
α-helix	574-581	8
α-helix	583	1
β-strand	588-589	2	29
β-strand	605-608	4	29
β-strand	611-615	5	29
α-helix	619-622	4
α-helix	629-636	8
α-helix	641-660	20
α-helix	666-669	4
α-helix	673-698	26
α-helix	710-736	27
α-helix	742-748	7
α-helix	755-762	8
α-helix	794-798	5
α-helix	810-844	35
β-strand	849	1	30
β-strand	857	1	30
α-helix	868-870	3
β-strand	873	1	31
β-strand	879	1	32
β-strand	882	1	33
α-helix	890-897	8
α-helix	907-909	3
α-helix	910-912	3
β-strand	913	1	34
α-helix	914-916	3
α-helix	923-946	24
β-strand	953	1	33
β-strand	956	1	32
α-helix	961-971	11
α-helix	977-978	2
β-strand	979	1	34
α-helix	983-996	14
α-helix	1005-1013	9
α-helix	1016-1025	10
α-helix	1028-1034	7
α-helix	1039-1054	16
β-strand	1057	1	31
α-helix	1058-1059	2
α-helix	1064-1073	10
α-helix	1074-1077	4
α-helix	1097-1105	9
β-strand	1116-1117	2	35
β-strand	1118-1119	2	36
β-strand	1120	1	37
α-helix	1128-1138	11
β-strand	1139	1	38
β-strand	1147-1154	8	39
α-helix	1167-1173	7
β-strand	1188	1	40
β-strand	1191-1197	7	39
α-helix	1200-1203	4
α-helix	1209-1218	10
β-strand	1224-1228	5	39
β-strand	1237-1242	6	39
β-strand	1243	1	40
α-helix	1257-1270	14
β-strand	1276	1	38
β-strand	1283	1	41
β-strand	1284	1	42
β-strand	1286-1292	7	43
β-strand	1298-1304	7	43
β-strand	1305-1306	2	36
β-strand	1307	1	41
β-strand	1322	1	37
β-strand	1328-1329	2	35
α-helix	1332-1339	8
α-helix	1341-1356	16
α-helix	1365-1376	12
α-helix	1396-1400	5
α-helix	1405-1415	11
β-strand	1418-1419	2	15
α-helix	1424-1429	6
α-helix	1437-1439	3
β-strand	1441-1445	5	44
α-helix	1447-1452	6

20 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Transcription initiation factor IIB	M	protein	345	Saccharomyces cerevisiae	P29055 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB1	A	protein	1733	Saccharomyces cerevisiae	P04050 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB2	B	protein	1224	Saccharomyces cerevisiae	P08518 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB3	C	protein	318	Saccharomyces cerevisiae	P16370 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	215	Saccharomyces cerevisiae	P20434
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	155	Saccharomyces cerevisiae	P20435
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	146	Saccharomyces cerevisiae	P20436
DNA-directed RNA polymerase II subunit RPB9	I	protein	122	Saccharomyces cerevisiae	P27999
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	70	Saccharomyces cerevisiae	P22139
DNA-directed RNA polymerase II subunit RPB11	K	protein	120	Saccharomyces cerevisiae	P38902
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	70	Saccharomyces cerevisiae	P40422
Transcription initiation factor IIF subunit alpha	Q	protein	735	Saccharomyces cerevisiae	P41895

18 more molecules are not listed.

Sequence of entity 1 (M), FASTA

>8UOQ_1 Transcription initiation factor IIB (chains M)
MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR
SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD
KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC
RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP
RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ
TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK

Sequence of entity 2 (A), FASTA

>8UOQ_2 DNA-directed RNA polymerase II subunit RPB1 (chains A)
MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGS
IDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNE
LMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLK
LVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLP
VPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHV
ATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLE
LDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKR
AGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNA
DFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTF
IELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSP
KDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHN
GFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVR
FLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFV
DRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRR
LVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVD
LLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNI
RRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCC
LLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMT
LNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEH
TTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRA
AMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHML
KKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGG
LTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGA
FDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGS
NDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTS
PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS
PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR

Sequence of entity 3 (B), FASTA

>8UOQ_3 DNA-directed RNA polymerase II subunit RPB2 (chains B)
MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQ
DIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLR
NLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCY
LSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEI
RSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEH
ICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEF
LPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTL
FKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVS
QVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLS
LMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETL
RTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAK
LMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEEND
LDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGV
FLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMI
MNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIA
PGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDG
LKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSR
MTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKK
LMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIA
HGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAA
KLLFQELMAMNITPRLYTDRSRDF

Sequence of entity 4 (C), FASTA

>8UOQ_4 DNA-directed RNA polymerase II subunit RPB3 (chains C)
MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD
EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI
VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY
DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV
DQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPY
SNASQMGNTGSGGYDNAW

Sequence of entity 5 (E), FASTA

>8UOQ_5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>8UOQ_6 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (H), FASTA

>8UOQ_7 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 8 (I), FASTA

>8UOQ_8 DNA-directed RNA polymerase II subunit RPB9 (chains I)
MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQ
DIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ
FS

Sequence of entity 9 (J), FASTA

>8UOQ_9 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 10 (K), FASTA

>8UOQ_10 DNA-directed RNA polymerase II subunit RPB11 (chains K)
MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAA
YKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF

Sequence of entity 11 (L), FASTA

>8UOQ_11 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Sequence of entity 12 (Q), FASTA

>8UOQ_12 Transcription initiation factor IIF subunit alpha (chains Q)
MSRRNPPGSRNGGGPTNASPFIKRDRMRRNFLRMRMGQNGSNSSSPGVPNGDNSRGSLVK
KDDPEYAEEREKMLLQIGVEADAGRSNVKVKDEDPNEYNEFPLRAIPKEDLENMRTHLLK
FQSKKKINPVTDFHLPVRLHRKDTRNLQFQLTRAEIVQRQKEISEYKKKAEQERSTPNSG
GMNKSGTVSLNNTVKDGSQTPTVDSVTKDNTANGVNSSIPTVTGSSVPPASPTTVSAVES
NGLSNGSTSAANGLDGNASTANLANGRPLVTKLEDAGPAEDPTKVGMVKYDGKEVTNEPE
FEEGTMDPLADVAPDGGGRAKRGNLRRKTRQLKVLDENAKKLRFEEFYPWVMEDFDGYNT
WVGSYEAGNSDSYVLLSVEDDGSFTMIPADKVYKFTARNKYATLTIDEAEKRMDKKSGEV
PRWLMKHLDNIGTTTTRYDRTRRKLKAVADQQAMDEDDRDDNSEVELDYDEEFADDEEAP
IIDGNEQENKESEQRIKKEMLQANAMGLRDEEAPSENEEDELFGEKKIDEDGERIKKALQ
KTELAALYSSDENEINPYLSESDIENKENESPVKKEEDSDTLSKSKRSSPKKQQKKATNA
HVHKEPTLRVKSIKNCVIILKGDKKILKSFPEGEWNPQTTKAVDSSNNASNTVPSPIKQE
EGLNSTVAEREETPAPTITEKDIIEAIGDGKVNIKEFGKFIRRKYPGAENKKLMFAIVKK
LCRKVGNDHMELKKE

Ligands and cofactors

ID	Name	Formula	Copies
MG	Magnesium ion	Mg	2
SF4	Iron/sulfur cluster	Fe4 S4	1
ZN	Zinc ion	Zn	15

Primary citation

Transcription start site scanning requires the fungi-specific hydrophobic loop of Tfb3. Yang, C., Basnet, P., Sharmin, S. et al. Nucleic Acids Res (2024) 52:11602-11611. DOI 10.1093/nar/gkae805 · PubMed

Other PDB entries of the same protein (UniProt P29055 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7O4J 2.9 Å, Yeast RNA polymerase II transcription pre-initiation complex (consensus)
7ML0 3.0 Å, RNA polymerase II pre-initiation complex (PIC1)
8CEN 3.0 Å, Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
7ML4 3.1 Å, RNA polymerase II initially transcribing complex (ITC)
7ZS9 3.1 Å, Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome…
7O4I 3.2 Å, Yeast RNA polymerase II transcription pre-initiation complex with initial transcription…
7O75 3.2 Å, Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA
7UI9 3.3 Å, Core Mediator-PICearly (Copy A)
7UIO 3.3 Å, Mediator-PIC Early (Composite Model)
4BBR 3.4 Å, Structure of RNA polymerase II-TFIIB complex
7ML2 3.4 Å, RNA polymerase II pre-initiation complex (PIC3)
7O72 3.4 Å, Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA

Browse structure collections

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