Structure and interactions of HIV-1 gp41 CHR-NHR reverse hairpin constructs reveal molecular determinants of antiviral activity. Determined by X-ray diffraction at 1.63 Å resolution. Released 5 Mar 2025.
Explore 8W2Y in 3D Show helices and sheets RCSB PDB PDBe
8W2Y contains 2 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 3-23 | 21 | |
| α-helix | 34-80 | 47 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Transmembrane protein gp41 | A | protein | 83 | Human immunodeficiency virus 1 | P04578 (AlphaFold model) |
>8W2Y_1 Transmembrane protein gp41 (chains A) PTSLIEELIRRSEEQQRRNEEALRREDSGGGRQLLSGIVQQQNNLLRAIEAQQHLLQLTV WGIKQLQARILAVERYLRDQQED
Structure and Interactions of HIV-1 gp41 CHR-NHR Reverse Hairpin Constructs Reveal Molecular Determinants of Antiviral Activity. He, L., McAndrew, R., Barbu, R. et al. J Mol Biol (2024) 436:168650-168650. DOI 10.1016/j.jmb.2024.168650 · PubMed
Other PDB entries of the same protein (UniProt P04578 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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