9NGE: PDB entry 9NGE

The ubiquitin-associated domain of human thirty-eight negative kinase-1 rigidly fused to a double trigger variant of the 1TEL crystallization chaperone. Determined by X-ray diffraction at 2.02 Å resolution. Released 26 Mar 2025.

Method: X-ray diffraction
Resolution: 2.02 Å
Organism: Homo sapiens
Chains: 2
Atoms: 2,424
Mol. weight: 39.11 kDa
Released: 26 Mar 2025

Explore 9NGE in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9NGE contains 22 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 11 helices, 0 β-strands

Element	Residues	Length
α-helix	18-20	3
α-helix	24-26	3
α-helix	29-42	14
α-helix	45-47	3
α-helix	57-60	4
α-helix	65-71	7
α-helix	76-100	25
α-helix	106-114	9
α-helix	120-136	17
α-helix	140-149	10
α-helix	154-162	9

Chain B: 11 helices, 0 β-strands

Element	Residues	Length
α-helix	18-20	3
α-helix	24-26	3
α-helix	29-42	14
α-helix	45-47	3
α-helix	57-60	4
α-helix	65-71	7
α-helix	76-100	25
α-helix	106-116	11
α-helix	120-135	16
α-helix	140-149	10
α-helix	154-163	10

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1	A, B	protein	165	Homo sapiens	P41212 (AlphaFold model), Q13470 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>9NGE_1 Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1 (chains A, B)
MGHHHHHHHHHHSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLSPIDSNTFEMNGKAL
LELTKEDFRYRSPHSGDELYELLQHILKEVQRKIMEVELSVHGVTHQEAQTALGATGGDV
VSAIRNLKVDQLFHLSSRSRADAWRILEHYQWDLSAASRYVLARP

Primary citation

The ubiquitin-associated domain of human thirty-eight negative kinase-1 rigidly fused to a double trigger variant of the 1TEL crystallization chaperone. Averett, J.C. To be published.

Other PDB entries of the same protein (UniProt P41212 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9DOC 1.19 Å, The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly…
9ZB7 1.24 Å, A DARPin fused to the 1TEL crystallization chaperone via a direct helical fusion
9Q4D 1.3 Å, A DARPin fused to the double trigger 1TEL variant crystallization chaperone via a direct…
7TW9 1.41 Å, Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to Sinefungin
1JI7 1.45 Å, Crystal Structure of TEL SAM Polymer
7TDY 1.53 Å, The ubiquitin-associated domain of human thirty-eight negative kinase 1, flexibly fused…
7TW8 1.55 Å, Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SAH
8FRJ 1.57 Å, Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946
9DB5 1.57 Å, A DARPin fused to the 1TEL crystallization chaperone via a proline-alanine linker
8FT8 1.6 Å, The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly…
8FRK 1.61 Å, Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC8158
7TW7 1.62 Å, Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SAM

Browse structure collections

About this viewer

MolViewer shows 9NGE directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.