9PA7: In situ human 80S consensus ribosome with EBP1
In situ human 80S consensus ribosome with EBP1. Determined by electron microscopy at 2.67 Å resolution. Released 24 Dec 2025.
- Method
- Electron microscopy
- Resolution
- 2.67 Å
- Organism
- Homo sapiens
- Chains
- 87
- Atoms
- 231,160
- Mol. weight
- 3804.34 kDa
- Ligands
- PUT, ZN, SPD, SPM
- Released
- 24 Dec 2025
Explore 9PA7 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9PA7 contains 593 α-helices and 619 β-strands across 81 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain CA: 11 helices, 23 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 15-38 | 24 | |
| β-strand | 44 | 1 | 95 |
| α-helix | 45-62 | 18 | |
| β-strand | 73-82 | 10 | 96 |
| β-strand | 85 | 1 | 97 |
| α-helix | 96-97 | 2 | |
| β-strand | 99 | 1 | 95 |
| β-strand | 105-114 | 10 | 96 |
| β-strand | 117-126 | 10 | 96 |
| β-strand | 135 | 1 | 98 |
| α-helix | 139-156 | 18 | |
| β-strand | 162 | 1 | 99 |
| α-helix | 163-176 | 14 | |
| β-strand | 180-181 | 2 | 96 |
| α-helix | 182 | 1 | |
| β-strand | 185-190 | 6 | 96 |
| β-strand | 191 | 1 | 100 |
| β-strand | 194 | 1 | 100 |
| β-strand | 200-203 | 4 | 96 |
| α-helix | 207-212 | 6 | |
| β-strand | 217 | 1 | 99 |
| β-strand | 222-231 | 10 | 96 |
| β-strand | 238 | 1 | 97 |
| β-strand | 246-249 | 4 | 101 |
| α-helix | 260-272 | 13 | |
| β-strand | 278-279 | 2 | 101 |
| α-helix | 280-282 | 3 | |
| α-helix | 289-298 | 10 | |
| β-strand | 302-305 | 4 | 101 |
| β-strand | 309 | 1 | 97 |
| β-strand | 316-325 | 10 | 96 |
| β-strand | 331-332 | 2 | 96 |
| β-strand | 343 | 1 | 98 |
| α-helix | 352-359 | 8 | |
Chain CD: 3 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-8 | 3 | |
| β-strand | 9 | 1 | 1 |
| α-helix | 18-20 | 3 | |
| α-helix | 27-36 | 10 | |
Chain CF: 13 helices, 33 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 7 | 1 | 23 |
| β-strand | 10-14 | 5 | 23 |
| α-helix | 20-31 | 12 | |
| α-helix | 36-49 | 14 | |
| α-helix | 52-54 | 3 | |
| α-helix | 64-69 | 6 | |
| β-strand | 76-81 | 6 | 23 |
| β-strand | 86-91 | 6 | 23 |
| α-helix | 99-107 | 9 | |
| β-strand | 111-117 | 7 | 23 |
| α-helix | 122-126 | 5 | |
| α-helix | 132-142 | 11 | |
| β-strand | 147-153 | 7 | 23 |
| α-helix | 165-181 | 17 | |
| β-strand | 189-193 | 5 | 23 |
| β-strand | 214-218 | 5 | 24 |
| β-strand | 221-225 | 5 | 24 |
| α-helix | 228-234 | 7 | |
| α-helix | 236-239 | 4 | |
| α-helix | 245-246 | 2 | |
| β-strand | 247 | 1 | 25 |
| β-strand | 249 | 1 | 26 |
| β-strand | 252-256 | 5 | 27 |
| β-strand | 260-267 | 8 | 27 |
| β-strand | 269 | 1 | 25 |
| β-strand | 272 | 1 | 28 |
| β-strand | 277-280 | 4 | 29 |
| β-strand | 285-288 | 4 | 29 |
| β-strand | 289-294 | 6 | 27 |
| β-strand | 297-298 | 2 | 27 |
| β-strand | 302 | 1 | 28 |
| β-strand | 306-312 | 7 | 27 |
| β-strand | 325 | 1 | 26 |
| β-strand | 326-328 | 3 | 29 |
| α-helix | 332-334 | 3 | |
| β-strand | 339-346 | 8 | 30 |
| β-strand | 353 | 1 | 31 |
| β-strand | 360-363 | 4 | 30 |
| β-strand | 366-369 | 4 | 30 |
| β-strand | 371-379 | 9 | 30 |
| β-strand | 386 | 1 | 30 |
| β-strand | 394 | 1 | 31 |
| β-strand | 399-405 | 7 | 30 |
| α-helix | 419-422 | 4 | |
| β-strand | 423-428 | 6 | 30 |
| β-strand | 431-442 | 12 | 30 |
Chain CI: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 52-62 | 11 | |
| α-helix | 69-72 | 4 | |
Chain La: 7 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 7-10 | 4 | |
| α-helix | 42-48 | 7 | |
| β-strand | 72-74 | 3 | 56 |
| α-helix | 75-81 | 7 | |
| α-helix | 84-92 | 9 | |
| β-strand | 97-98 | 2 | 150 |
| β-strand | 100-102 | 3 | 57 |
| α-helix | 103-106 | 4 | |
| β-strand | 110-112 | 3 | 56 |
| β-strand | 123-126 | 4 | 57 |
| β-strand | 128-129 | 2 | 56 |
| α-helix | 131-139 | 9 | |
| β-strand | 143-146 | 4 | 57 |
Chain LA: 11 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-5 | 2 | |
| α-helix | 29-32 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 61 |
| α-helix | 50-51 | 2 | |
| β-strand | 58-64 | 7 | 61 |
| β-strand | 71-77 | 7 | 61 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 62 |
| β-strand | 83 | 1 | 63 |
| β-strand | 87-91 | 5 | 61 |
| β-strand | 101-103 | 3 | 61 |
| α-helix | 104-106 | 3 | |
| β-strand | 112-113 | 2 | 64 |
| β-strand | 116-117 | 2 | 65 |
| β-strand | 124-126 | 3 | 65 |
| β-strand | 134-140 | 7 | 64 |
| α-helix | 142-144 | 3 | |
| β-strand | 145-149 | 5 | 64 |
| β-strand | 155-159 | 5 | 64 |
| β-strand | 163-165 | 3 | 61 |
| β-strand | 166 | 1 | 64 |
| β-strand | 169 | 1 | 62 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-190 | 9 | |
| α-helix | 201-203 | 3 | |
| β-strand | 224-225 | 2 | 66 |
| α-helix | 229-230 | 2 | |
| β-strand | 237-238 | 2 | 66 |
Chain Lb: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-18 | 7 | |
| α-helix | 22-24 | 3 | |
| α-helix | 37-48 | 12 | |
| α-helix | 54-73 | 20 | |
| α-helix | 92-100 | 9 | |
| α-helix | 106-117 | 12 | |
Chain LB: 18 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-10 | 2 | |
| α-helix | 14-16 | 3 | |
| α-helix | 32-35 | 4 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 79 |
| β-strand | 45-59 | 15 | 80 |
| β-strand | 71-80 | 10 | 80 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 81 |
| β-strand | 98-106 | 9 | 81 |
| α-helix | 112-116 | 5 | |
| α-helix | 134-137 | 4 | |
| α-helix | 140-156 | 17 | |
| β-strand | 159-165 | 7 | 81 |
| α-helix | 168-170 | 3 | |
| β-strand | 180-184 | 5 | 81 |
| β-strand | 185-186 | 2 | 79 |
| α-helix | 190-199 | 10 | |
| β-strand | 204-205 | 2 | 81 |
| α-helix | 207-209 | 3 | |
| β-strand | 216-222 | 7 | 80 |
| α-helix | 223-225 | 3 | |
| β-strand | 228-229 | 2 | 82 |
| α-helix | 231-234 | 4 | |
| α-helix | 237-241 | 5 | |
| β-strand | 270-271 | 2 | 82 |
| β-strand | 276-288 | 13 | 80 |
| β-strand | 292-293 | 2 | 83 |
| β-strand | 297-298 | 2 | 83 |
| α-helix | 300-302 | 3 | |
| α-helix | 316 | 1 | |
| β-strand | 320 | 1 | 84 |
| β-strand | 324 | 1 | 84 |
| β-strand | 330-334 | 5 | 80 |
| β-strand | 344-349 | 6 | 80 |
| β-strand | 365-368 | 4 | 80 |
| α-helix | 382-389 | 8 | |
| α-helix | 393-402 | 10 | |
73 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| SERPINE1 mRNA-binding protein 1 | CD | protein | 36 | Homo sapiens | Q8NC51 (AlphaFold model) |
| Transcription factor BTF3 | CI | protein | 31 | Homo sapiens | P20290 (AlphaFold model) |
| Elongation factor 1-alpha 1 | CF | protein | 441 | Homo sapiens | P68104 (AlphaFold model) |
| 28S rRNA | L5 | RNA | 5070 | Homo sapiens | |
| 5S rRNA | L7 | RNA | 120 | Homo sapiens | |
| 5.8S rRNA | L8 | RNA | 156 | Homo sapiens | |
| 60S ribosomal protein L8 | LA | protein | 248 | Homo sapiens | P62917 (AlphaFold model) |
| Large ribosomal subunit protein uL3 | LB | protein | 402 | Homo sapiens | P39023 |
| 60S ribosomal protein L4 | LC | protein | 368 | Homo sapiens | P36578 |
| Large ribosomal subunit protein uL18 | LD | protein | 293 | Homo sapiens | P46777 |
| Large ribosomal subunit protein eL6 | LE | protein | 250 | Homo sapiens | Q02878 |
| 60S ribosomal protein L7 | LF | protein | 225 | Homo sapiens | P18124 |
75 more molecules are not listed.
Sequence of entity 1 (CD), FASTA
>9PA7_1 SERPINE1 mRNA-binding protein 1 (chains CD)
PGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENK
Sequence of entity 2 (CI), FASTA
>9PA7_2 Transcription factor BTF3 (chains CI)
IMNQEKLAKLQAQVRIGGKGTARRKKKVVHR
Sequence of entity 3 (CF), FASTA
>9PA7_3 Elongation factor 1-alpha 1 (chains CF)
EKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKL
KAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEF
EAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGY
NPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTD
KPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEAL
PGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDC
HTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGR
FAVRDMRQTVAVGVIKAVDKK
Sequence of entity 4 (L5), FASTA
>9PA7_4 28S rRNA (chains L5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAG
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGCGGGGCGCGGGACAUGUGGCGUACGGAAGACCCGCUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGC
GGGUCCGGCCGUGUCGGCGGCCCGGCGGAUCUUUCCCGCCCCCCGUUCCUCCCGACCCCU
CCACCCGCCCUCCCUUCCCCCGCCGCCCCUCCUCCUCCUCCCCGGAGGGGGCGGGCUCCG
GCGGGUGCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCGUCCCCCGA
CCGGCGACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCG
GGACGGCUGGGAAGGCCCGGCGGGGAAGGUGGCUCGGGGGGCCCCGUCCGUCCGUCCGUC
CGUCCUCCUCCUCCCCCGUCUCCGCCCCCCGGCCCCGCGUCCUCCCUCGGGAGGGCGCGC
GGGUCGGGGCGGCGGCGGCGGCGGCGGUGGCGGCGGCGGCGGCGGCGGCGGGACCGAAAC
CCCCCCCGAGUGUUACAGCCCCCCCGGCAGCAGCACUCGCCGAAUCCCGGGGCCGAGGGA
GCGAGACCCGUCGCCGCGCUCUCCCCCCUCCCGGCGCCCACCCCCGCGGGGAAUCCCCCG
CGAGGGGGGUCUCCCCCGCGGGGGCGCGCCGGCGUCUCCUCGUGGGGGGGCCGGGCCACC
CCUCCCACGGCGCGACCGCUCUCCCACCCCUCCUCCCCGCGCCCCCGCCCCGGCGACGGG
GGGGGUGCCGCGCGCGGGUCGGGGGGCGGGGCGGACUGUCCCCAGUGCGCCCCGGGCGGG
UCGCGCCGUCGGGCCCGGGGGAGGUUCUCUCGGGGCCACGCGCGCGUCCCCCGAAGAGGG
GGACGGCGGAGCGAGCGCACGGGGUCGGCGGCGACGUCGGCUACCCACCCGACCCGUCUU
GAAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCCGCCG
UGGCGCAAUGAAGGUGAAGGCCGGCGCGCUCGCCGGCCGAGGUGGGAUCCCGAGGCCUCU
CCAGUCCGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCA
CGAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGGCAGGGCGAAGCCAGA
GGAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGGU
AUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCAG
GAUAGCUGGCGCUCUCGCAGACCCGACGCACCCCCGCCACGCAGUUUUAUCCGGUAAAGC
GAAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGU
AAGAAGCCCGGCUCGCUGGCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACU
UUUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGC
CGACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAU
GGAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGA
AAAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCCGGCAGUCGAGAGUGGA
CGGGAGCGGCGGGGGCGGCGCGCGCGCGCGCGCGUGUGGUGUGCGUCGGAGGGCGGCGGC
GGCGGCGGCGGCGGGGGUGUGGGGUCCUUCCCCCGCCCCCCCCCCCACGCCUCCUCCCCU
CCUCCCGCCCACGCCCCGCUCCCCGCCCCCGGAGCCCCGCGGACGCUACGCCGCGACGAG
UAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGC
AGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGG
AGAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGA
GCGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGCCCUCGGCCGAUCGAAAGGGAGUC
GGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCGGU
AACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUGUG
AAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCG
UCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGG
UGUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUC
UGGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAU
AAGGAUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGGGCGCGAAGCGGGGCUGGGCGCGC
GCCGCGGCUGGACGAGGCGCCGCCGCCCCCCCCACGCCCGGGGCACCCCCCUCGCGGCCC
UCCCCCGCCCCACCCCGCGCGCGCCGCUCGCUCCCUCCCCGCCCCGCGCCCUCUCUCUCU
CUCUCUCCCCCGCUCCCCGUCCUCCCCCCUCCCCGGGGGAGCGCCGCGUGGGGGCGGCGG
CGGGGGGAGAAGGGUCGGGGCGGCAGGGGCCGGCGGCGGCCCGCCGCGGGGCCCCGGCGG
CGGGGGCACGGUCCCCCGCGAGGGGGGCCCGGGCACCCGGGGGGCCGGCGGCGGCGGCGA
CUCUGGACGCGAGCCGGGCCCUUCCCGUGGAUCGCCCCAGCUGCGGCGGGCGUCGCGGCC
GCCCCCGGGGAGCCCGGCGGGCGCCGGCGCGCCCCCCCCCCCACCCCACGUCUCGUCGCG
CGCGCGUCCGCUGGGGGCGGGGAGCGGUCGGGCGGCGGCGGUCGGCGGGCGGCGGGGCGG
GGCGGUUCGUCCCCCCGCCCUACCCCCCCGGCCCCGUCCGCCCCCCGUUCCCCCCUCCUC
CUCGGCGCGCGGCGGCGGCGGCGGCAGGCGGCGGAGGGGCCGCGGGCCGGUCCCCCCCGC
CGGGUCCGCCCCCGGGGCCGCGGUUCCGCGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAG
CCGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUUAAUUAAAACAAAGCAUCGC
GAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAG
UGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAG
CCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAXGGAUGAACGAGAUUCCCACUGU
CCCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGGCUUGGCGGAAUCAGCGGGG
AAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUGAAGAGACAUGAGAGGUGUA
GAAUAAGUGGGAGGCCCCCGGCGCCCCCCCGGUGUCCCCGCGAGGGGCCCGGGGCGGGGU
CCGCCGGCCCUGCGGGCCGCCGGUGAAAUACCACUACUCUGAUCGUUUUUUCACUGACCC
GGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUCUCGCUUCUGGCGCCAAGCGCCCGGCCGC
GCGCCGGCCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCG
GUACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCU
CCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCG
UGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAA
AGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUG
AUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGU
UCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUAC
CCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUU
CAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGG
AUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCG
CGGAGCCUCGGUUGGCCUCGGAUAGCCGGUCCCCCGCCUGUCCCCGCCGGCGGGCCGCCC
CCCCCCUCCACGCGCCCCGCGCGCGCGGGAGGGCGCGUGCCCCGCCGCGCGCCGGGACCG
GGGUCCGGUGCGGAGUGCCCUUCGUCCUGGGAAACGGGGCGCGGCCGGAGAGGCGGCCGC
CCCCUCGCCCGUCACGCACCGCACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGAC
GACCUGCUUCUGGGUCGGGG
Sequence of entity 5 (L7), FASTA
>9PA7_5 5S rRNA (chains L7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 6 (L8), FASTA
>9PA7_6 5.8S rRNA (chains L8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCU
Sequence of entity 7 (LA), FASTA
>9PA7_7 60S ribosomal protein L8 (chains LA)
GRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKV
VFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPG
DRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILK
AGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAAR
RTGRLRGT
Sequence of entity 8 (LB), FASTA
>9PA7_8 Large ribosomal subunit protein uL3 (chains LB)
SHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVD
RPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKN
WHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHLM
EIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLP
RKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKN
NASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALE
KIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
Sequence of entity 9 (LC), FASTA
>9PA7_9 60S ribosomal protein L4 (chains LC)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKL
APGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVDKAAAAAAA
LQAKSDEK
Sequence of entity 10 (LD), FASTA
>9PA7_10 Large ribosomal subunit protein uL18 (chains LD)
GFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDII
CQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEG
QVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFP
GYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMMEEMYK
KAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERA
Sequence of entity 11 (LE), FASTA
>9PA7_11 Large ribosomal subunit protein eL6 (chains LE)
KGKPHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYSAAKSKVEKKKKEKVLATVTKPVGG
DKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHR
GKRVVFLKQLASGLLLVTGPLVLNRVPLRRTHQKFVIATSTKIDISNVKIPKHLTDAYFK
KKKLRKPRHQEGEIFDTEKEKYEITEQRKIDQKAVDSQILPKIKAIPQLQGYLRSVFALT
NGIYPHKLVF
Sequence of entity 12 (LF), FASTA
>9PA7_12 60S ribosomal protein L7 (chains LF)
NFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYV
PAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWG
YPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKE
ANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| PUT | 1,4-diaminobutane | C4 H12 N2 | 1 |
| ZN | Zinc ion | Zn | 7 |
| SPD | Spermidine | C7 H19 N3 | 12 |
| SPM | Spermine | C10 H26 N4 | 8 |
| MG | Magnesium ion | Mg | 225 |
Water and common crystallization additives (K) are not listed.
Primary citation
Visualizing the translation landscape in human cells at high resolution. Zheng, W., Zhang, Y., Wang, J. et al. Nat Commun (2025) 16:10757-10757. DOI 10.1038/s41467-025-65795-9 · PubMed
Other PDB entries of the same protein (UniProt Q8NC51 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 29IZ 2.08 Å, Dormant 80S:eEF2:SERBP1:tRNA complex from human cells treated with toxin NT-2
- 9PBE 2.19 Å, In situ human 80S ribosome (composite map)
- 8K2C 2.4 Å, Cryo-EM structure of the human 80S ribosome with Tigecycline
- 8XSX 2.4 Å, Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2
- 9P7D 2.57 Å, In situ human Hibernating class4 80S ribosome
- 9P7E 2.59 Å, In situ human Hibernating class5 80S ribosome
- 9T6D 2.67 Å, NAA40-NAC bound human 80S (combined translation states)
- 9P7C 2.78 Å, In situ human Hibernating class3 80S ribosome
- 9P7A 2.81 Å, In situ human hibernating class2 80S ribosome
- 9B0P 2.82 Å, In situ human Hibernating class1 80S ribosome
- 9FQZ 2.85 Å, cryo-EM structure of HCT15 polysomes bound to EEF2, EBP1, and SERBP1
- 6Z6N 2.9 Å, Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)
Browse structure collections
About this viewer
MolViewer shows 9PA7 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.