9WBZ: NCP-motor-ARP module of ncBAF-nucleosome complex
The structure of NCP-motor-ARP module of ncBAF-nucleosome complex. Determined by electron microscopy at 2.9 Å resolution. Released 18 Feb 2026.
- Method
- Electron microscopy
- Resolution
- 2.9 Å
- Organisms
- Homo sapiens, Xenopus laevis, unidentified
- Chains
- 14
- Atoms
- 24,573
- Mol. weight
- 530.34 kDa
- Released
- 18 Feb 2026
Explore 9WBZ in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9WBZ contains 132 α-helices and 82 β-strands across 12 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A: 36 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 455-515 | 61 | |
| α-helix | 543-545 | 3 | |
| α-helix | 546-557 | 12 | |
| α-helix | 732-735 | 4 | |
| α-helix | 756-770 | 15 | |
| β-strand | 776-777 | 2 | 1 |
| α-helix | 785-798 | 14 | |
| β-strand | 807-809 | 3 | 1 |
| α-helix | 812-825 | 14 | |
| β-strand | 831-833 | 3 | 1 |
| α-helix | 838-843 | 6 | |
| α-helix | 845-850 | 6 | |
| β-strand | 855-858 | 4 | 1 |
| α-helix | 860-865 | 6 | |
| α-helix | 867-870 | 4 | |
| β-strand | 878-881 | 4 | 1 |
| α-helix | 883-887 | 5 | |
| α-helix | 892-900 | 9 | |
| β-strand | 906-909 | 4 | 1 |
| α-helix | 919-928 | 10 | |
| α-helix | 936-938 | 3 | |
| α-helix | 963-972 | 10 | |
| α-helix | 981-984 | 4 | |
| β-strand | 992-996 | 5 | 2 |
| α-helix | 999-1001 | 3 | |
| α-helix | 1002-1014 | 13 | |
| β-strand | 1017-1018 | 2 | 3 |
| β-strand | 1032-1033 | 2 | 3 |
| α-helix | 1038-1047 | 10 | |
| α-helix | 1049-1052 | 4 | |
| α-helix | 1055-1063 | 9 | |
| α-helix | 1073-1078 | 6 | |
| α-helix | 1080-1094 | 15 | |
| β-strand | 1099-1103 | 5 | 2 |
| α-helix | 1106-1119 | 14 | |
| β-strand | 1123-1126 | 4 | 2 |
| α-helix | 1132-1143 | 12 | |
| β-strand | 1151-1155 | 5 | 2 |
| α-helix | 1156-1159 | 4 | |
| β-strand | 1170-1173 | 4 | 2 |
| α-helix | 1180-1187 | 8 | |
| α-helix | 1198-1199 | 2 | |
| β-strand | 1200-1204 | 5 | 2 |
| α-helix | 1210-1221 | 12 | |
| α-helix | 1224-1225 | 2 | |
| α-helix | 1226-1230 | 5 | |
| α-helix | 1242-1254 | 13 | |
| α-helix | 1268-1273 | 6 | |
| α-helix | 1277-1293 | 17 | |
| α-helix | 1311-1315 | 5 | |
Chain B: 5 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 17-21 | 5 | |
| α-helix | 25-28 | 4 | |
| α-helix | 31-41 | 11 | |
| β-strand | 45-46 | 2 | 4 |
| α-helix | 50-75 | 26 | |
| β-strand | 80-81 | 2 | 5 |
| α-helix | 83-92 | 10 | |
| β-strand | 97-98 | 2 | 6 |
Chain C: 5 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 17-21 | 5 | |
| α-helix | 27-36 | 10 | |
| β-strand | 42-43 | 2 | 7 |
| α-helix | 46-72 | 27 | |
| β-strand | 77-78 | 2 | 8 |
| α-helix | 80-89 | 10 | |
| α-helix | 91-96 | 6 | |
| β-strand | 100-102 | 3 | 9 |
Chains D and H: 4 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 38-48 | 11 | |
| β-strand | 53-54 | 2 | 8 |
| α-helix | 56-83 | 28 | |
| β-strand | 88-89 | 2 | 7 |
| α-helix | 91-101 | 11 | |
| α-helix | 105-123 | 19 | |
Chain E: 4 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 45-56 | 12 | |
| α-helix | 64-76 | 13 | |
| β-strand | 83-84 | 2 | 10 |
| α-helix | 86-113 | 28 | |
| β-strand | 118-119 | 2 | 11 |
| α-helix | 121-131 | 11 | |
Chain F: 5 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 19-22 | 4 | |
| α-helix | 26-28 | 3 | |
| α-helix | 31-40 | 10 | |
| β-strand | 45-46 | 2 | 11 |
| α-helix | 50-75 | 26 | |
| β-strand | 80-81 | 2 | 10 |
| α-helix | 83-92 | 10 | |
| β-strand | 96-98 | 3 | 9 |
Chain G: 5 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 17-20 | 4 | |
| α-helix | 27-36 | 10 | |
| β-strand | 42-43 | 2 | 12 |
| α-helix | 46-72 | 27 | |
| β-strand | 77-78 | 2 | 13 |
| α-helix | 80-88 | 9 | |
| α-helix | 91-96 | 6 | |
| β-strand | 101-102 | 2 | 6 |
Chain K: 6 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 41-42 | 2 | |
| α-helix | 45-48 | 4 | |
| α-helix | 50-54 | 5 | |
| α-helix | 64-78 | 15 | |
| β-strand | 83-84 | 2 | 5 |
| α-helix | 86-113 | 28 | |
| β-strand | 118-119 | 2 | 4 |
| α-helix | 121-131 | 11 | |
3 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Isoform 2 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A… | A | protein | 1614 | Homo sapiens | P51532 (AlphaFold model) |
| Histone H4 | B, F | protein | 102 | Xenopus laevis | P62799 (AlphaFold model) |
| Histone H2A | C, G | protein | 129 | Xenopus laevis | Q6AZJ8 (AlphaFold model) |
| Histone H2B 1.1 | D, H | protein | 125 | Xenopus laevis | P02281 (AlphaFold model) |
| Histone H3.2 | E, K | protein | 135 | Xenopus laevis | P84233 |
| DNA (207-mer) | I | DNA | 207 | unidentified | |
| DNA (207-mer) | J | DNA | 207 | unidentified | |
| Actin, cytoplasmic 1 | L | protein | 375 | Homo sapiens | P60709 |
| Actin-like protein 6A | N | protein | 429 | Homo sapiens | O96019 |
| B-cell CLL/lymphoma 7 protein family member A | O | protein | 210 | Homo sapiens | Q4VC05 |
Sequence of entity 1 (A), FASTA
>9WBZ_1 Isoform 2 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (chains A)
MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEE
DEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAE
VERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKR
KRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYK
DSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLC
QNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSV
KVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
Sequence of entity 2 (B, F), FASTA
>9WBZ_2 Histone H4 (chains B, F)
SGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKV
FLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sequence of entity 3 (C, G), FASTA
>9WBZ_3 Histone H2A (chains C, G)
SGRGKQGGKTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKKT
ESSKSAKSK
Sequence of entity 4 (D, H), FASTA
>9WBZ_4 Histone H2B 1.1 (chains D, H)
PEPAKSAPAPKKGSKKAVTKTQKKDGKKRRKSRKESYAIYVYKVLKQVHPDTGISSKAMS
IMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTK
YTSAK
Sequence of entity 5 (E, K), FASTA
>9WBZ_5 Histone H3.2 (chains E, K)
ARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTEL
LIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIM
PKDIQLARRIRGERA
Sequence of entity 6 (I), FASTA
>9WBZ_6 DNA (207-MER) (chains I)
GGACCCTATACGCGGCCGCCCTGGAGAATCCCGGTGCCGAGGCCGCTCAATTGGTCGTAG
ACAGCTCTAGCACCGCTTAAACGCACGTACGCGCTGTCCCCCGCGTTTTAACCGCCAAGG
GGATTACTCCCTAGTCTCCAGGCACGTGTCAGATATATACATCCTGAATCACCCCACGAA
GTACTAGAGGATCATAATCAGCCATAC
Sequence of entity 7 (J), FASTA
>9WBZ_7 DNA (207-MER) (chains J)
GTATGGCTGATTATGATCCTCTAGTACTTCGTGGGGTGATTCAGGATGTATATATCTGAC
ACGTGCCTGGAGACTAGGGAGTAATCCCCTTGGCGGTTAAAACGCGGGGGACAGCGCGTA
CGTGCGTTTAAGCGGTGCTAGAGCTGTCTACGACCAATTGAGCGGCCTCGGCACCGGGAT
TCTCCAGGGCGGCCGCGTATAGGGTCC
Sequence of entity 8 (L), FASTA
>9WBZ_8 Actin, cytoplasmic 1 (chains L)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF
Sequence of entity 9 (N), FASTA
>9WBZ_9 Actin-like protein 6A (chains N)
MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDK
GKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPV
LMSEAPWNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAI
PVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRK
EKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAE
RLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSF
TDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGG
KQCVERKCP
Sequence of entity 10 (O), FASTA
>9WBZ_10 B-cell CLL/lymphoma 7 protein family member A (chains O)
MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
SAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA
ETSAISQDLEGVPPSKKMKLEASQQNSEEM
Primary citation
ncBAF recognizes the nucleosome through BCL7A in chromatin remodeling. Chen, K., Du, L., Liu, Y. et al. Cell Discov (2025) 11:102-102. DOI 10.1038/s41421-025-00858-1 · PubMed
Other PDB entries of the same protein (UniProt P51532 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7TAB 1.16 Å, G-925 bound to the SMARCA4 (BRG1) Bromodomain
- 2GRC 1.5 Å, 1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF…
- 6ZS2 1.57 Å, Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in…
- 7TD9 1.61 Å, G-059 bound to the SMARCA4 (BRG1) Bromodomain
- 6HR2 1.76 Å, Crystal structure of PROTAC 2 in complex with the bromodomain of human SMARCA4 and…
- 3UVD 1.85 Å, Crystal Structure of the bromodomain of human Transcription activator BRG1 (SMARCA4) in…
- 5DKD 2.0 Å, Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3…
- 5EA1 2.0 Å, Crystal Structure of SMARCA4 bromodomain in complex with MPD
- 9DTX 2.11 Å, Crystal structure of PRT3789 in complex with the bromodomain of human BRG1 (SMARCA4) and…
- 7VRB 2.39 Å, Structure of the Human BRG1/SS18 complex
- 9UXC 2.74 Å, The ADP-bound structure of BCL7B-containing ARP module of the human SWI/SNF complex
- 7VDT 2.8 Å, The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
Browse structure collections
About this viewer
MolViewer shows 9WBZ directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.