If kappa light chain (Igkc) is a 219-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A2NHM3.
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The mean pLDDT of this model is 96.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 97% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6PXR | X-ray | 1.56 Å | L=1-219 |
| 4TPR | X-ray | 1.6 Å | L=1-218 |
| 4TQE | X-ray | 1.6 Å | L=1-218 |
| 3UO1 | X-ray | 1.64 Å | L=1-219 |
| 3V4U | X-ray | 1.64 Å | L=1-219 |
| 2IPU | X-ray | 1.65 Å | K/L=1-219 |
| 2DQU | X-ray | 1.7 Å | L=1-219 |
| 3UYR | X-ray | 1.7 Å | L=1-219 |
| 3V52 | X-ray | 1.7 Å | L=1-219 |
| 1ZEA | X-ray | 1.78 Å | L=1-216 |
| 1PZ5 | X-ray | 1.8 Å | A=1-216 |
| 2DQT | X-ray | 1.8 Å | L=1-219 |
| 1T2Q | X-ray | 1.83 Å | L=1-217 |
| 1F3D | X-ray | 1.87 Å | J/L=1-219 |
| 2OK0 | X-ray | 1.89 Å | L=1-219 |
| 3EYS | X-ray | 1.95 Å | L=1-219 |
| 4P3D | X-ray | 1.95 Å | B/L=1-217 |
| 1NBV | X-ray | 2.0 Å | L=1-219 |
| 3WE6 | X-ray | 2.02 Å | B=1-217 |
| 2R0Z | X-ray | 2.1 Å | L=1-219 |
Showing 20 of 39 experimental structures (best resolution first).
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