D0G6S1: Dynactin subunit 6 (DCTN6)

Dynactin subunit 6 (DCTN6) is a 190-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: D0G6S1.

Gene
DCTN6
Organism
Sus scrofa
Length
190 residues
Mean pLDDT
70.7
Model
AF-D0G6S1-F1 v6
Model created
1 Aug 2025
PDB structures
22

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Model confidence (pLDDT)

The mean pLDDT of this model is 70.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate5%
70 to 90Confident: backbone generally right57%
50 to 70Low: treat with caution11%
Below 50Very low: often disordered regions28%

What pLDDT means and how to read it

Function

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules

Subunit structure

Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3 (PubMed:25814576, PubMed:29420470, PubMed:33734450, PubMed:36071160). The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its…

Subcellular location

Cytoplasm, cytoskeleton, Chromosome, centromere, kinetochore

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7Z8MEM3.37 ÅU=1-190
5AFUEM3.5 ÅU=13-185
6F1TEM3.5 ÅU=1-190
8PR4EM3.5 ÅU=1-190
6ZNLEM3.8 ÅU=1-190
9DGSEM3.9 ÅU=1-190
5ADXEM4.0 ÅU=1-190
9YNGEM4.07 ÅU=1-190
6ZNMEM4.1 ÅU=1-190
6ZNNEM4.5 ÅU=1-190
9HHLEM6.53 ÅU=1-190
6F38EM6.7 ÅU=1-190
6ZNOEM6.8 ÅU=8-174
9DGUEM7.1 ÅU=1-190
9DGTEM7.2 ÅU=1-190
6F3AEM8.2 ÅU=1-190
6ZO4EM8.2 ÅU=1-190
5NW4EM8.7 Åg=1-190
9DGVEM8.8 ÅU=1-190
8PTKEM10.0 ÅU=1-190

Showing 20 of 22 experimental structures (best resolution first).

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