DNA-directed RNA polymerase subunit beta (POLR2B) is a 1251-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: I3LGP4.
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The mean pLDDT of this model is 86.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 69% |
| 70 to 90 | Confident: backbone generally right | 20% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 8% |
What pLDDT means and how to read it
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9MLC | EM | 2.4 Å | B=1-1300 |
| 7NVU | EM | 2.5 Å | B=127-1300 |
| 8B3D | EM | 2.6 Å | B=134-1300 |
| 7OOB | EM | 2.7 Å | B=127-1300 |
| 8UHG | EM | 2.7 Å | B=127-1300 |
| 8UI0 | EM | 2.7 Å | B=127-1300 |
| 8WAV | EM | 2.72 Å | p=127-1300 |
| 8WAX | EM | 2.75 Å | p=127-1300 |
| 8WAZ | EM | 2.76 Å | p=127-1300 |
| 7F4G | EM | 2.78 Å | B=127-1300 |
| 8WAU | EM | 2.78 Å | p=127-1300 |
| 7B7U | EM | 2.8 Å | B=127-1300 |
| 7NVS | EM | 2.8 Å | B=127-1300 |
| 7OO3 | EM | 2.8 Å | B=127-1300 |
| 8OEW | EM | 2.8 Å | B=50-1300 |
| 8UHD | EM | 2.8 Å | B=127-1300 |
| 8WAT | EM | 2.82 Å | p=127-1300 |
| 8WAY | EM | 2.85 Å | p=127-1300 |
| 8OEV | EM | 2.86 Å | B=50-1300 |
| 7NVT | EM | 2.9 Å | B=127-1300 |
Showing 20 of 75 experimental structures (best resolution first).
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