Butyrophilin subfamily 3 member A1 (BTN3A1) is a 513-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O00481.
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The mean pLDDT of this model is 89.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 68% |
| 70 to 90 | Confident: backbone generally right | 26% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate
Homodimer
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6ITA | X-ray | 1.2 Å | A=328-513 |
| 6ISM | X-ray | 1.25 Å | A=328-513 |
| 4N7I | X-ray | 1.4 Å | A=328-513 |
| 8IZE | X-ray | 1.4 Å | A=328-513 |
| 4N7U | X-ray | 1.46 Å | A=328-513 |
| 5LYG | X-ray | 1.6 Å | A=327-513 |
| 8IZG | X-ray | 1.6 Å | A=328-513 |
| 5LYK | X-ray | 1.7 Å | A=327-513 |
| 8IXV | X-ray | 1.72 Å | A=328-513 |
| 4K55 | X-ray | 1.91 Å | A=28-143 |
| 5HM7 | X-ray | 1.93 Å | A/B=272-513 |
| 4F80 | X-ray | 1.94 Å | A=30-246 |
| 5ZXK | X-ray | 1.96 Å | A=328-513 |
| 4JKW | X-ray | 2.01 Å | A=28-143 |
| 4V1P | X-ray | 2.04 Å | A=325-512 |
| 8JYE | X-ray | 2.18 Å | C/D=328-513 |
| 8JYC | X-ray | 2.29 Å | C/D=328-513 |
| 6J06 | X-ray | 2.65 Å | A/B/C=328-513 |
| 6XLQ | X-ray | 3.0 Å | A/D/G/J=30-255 |
| 8ZHR | EM | 3.0 Å | F=30-513 |
Showing 20 of 44 experimental structures (best resolution first).
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