O75694: Nuclear pore complex protein Nup155 (NUP155)

Nuclear pore complex protein Nup155 (NUP155) is a 1391-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O75694.

Gene
NUP155
Organism
Homo sapiens
Length
1391 residues
Mean pLDDT
83.1
Model
AF-O75694-F1 v6
Model created
1 Aug 2025
PDB structures
10

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Model confidence (pLDDT)

The mean pLDDT of this model is 83.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate52%
70 to 90Confident: backbone generally right34%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions10%

What pLDDT means and how to read it

Function

Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport

Subunit structure

Interacts with GLE1. Able to form a heterotrimer with GLE1 and NUP42 in vitro. Forms a complex with NUP35, NUP93, NUP205 and lamin B

Subcellular location

Nucleus, nuclear pore complex, Nucleus membrane

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7R1YEM3.0 ÅA=2-1391
7EYEEM5.1 ÅA=1-863
7EYFEM5.3 ÅA=864-1391
7EYQEM5.4 ÅA=1-1391
7R5KEM12.0 ÅD0/D1/D2/D3/D4/D5=1-1391
5IJNEM21.4 ÅA/B/E/K/Q/W=1-1391
5IJOEM21.4 ÅA/B/E/K/Q/W=1-1391
5A9QEM23.0 ÅA/B=1-1391
7PEREM35.0 ÅE/K/Q/W=1-1391
7R5JEM50.0 ÅD0/D1/D2/D3/D4/D5=1-1391

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