Enterotoxin type B (entB) is a 266-residue protein from Staphylococcus aureus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P01552.
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The mean pLDDT of this model is 91.5 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 81% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines (PubMed:2303780, PubMed:25015819). Also causes the intoxication staphylococcal food poisoning syndrome (By similarity)
Interacts with MHC class II molecules composed of alpha/HLA-DRA and beta/HLA-DRB1 chains (PubMed:25015819, PubMed:8152483). Interacts with T-cell receptor beta variable 19/TRBV19 (PubMed:25015819, PubMed:9881971)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3SEB | X-ray | 1.48 Å | A=28-265 |
| 8YBO | X-ray | 1.59 Å | A/C=28-266 |
| 4RGO | X-ray | 1.8 Å | S=28-266 |
| 1SE4 | X-ray | 1.9 Å | A=28-266 |
| 3GP7 | X-ray | 1.9 Å | A/B=28-266 |
| 1D5M | X-ray | 2.0 Å | C=28-266 |
| 1D5Z | X-ray | 2.0 Å | C=28-266 |
| 1GOZ | X-ray | 2.0 Å | A/B=28-266 |
| 8YBM | X-ray | 2.04 Å | A/C=28-266 |
| 8YKT | X-ray | 2.04 Å | A=28-266 |
| 8YBP | X-ray | 2.08 Å | A=28-266 |
| 8YBN | X-ray | 2.18 Å | A=28-266 |
| 1SE3 | X-ray | 2.3 Å | A=28-266 |
| 8YBL | X-ray | 2.33 Å | A=28-266 |
| 1SBB | X-ray | 2.4 Å | B/D=28-266 |
| 1D5X | X-ray | 2.45 Å | C=28-266 |
| 1D6E | X-ray | 2.45 Å | C=28-266 |
| 2SEB | X-ray | 2.5 Å | D=28-266 |
| 4RGM | X-ray | 2.69 Å | A/S=28-266 |
| 1SEB | X-ray | 2.7 Å | D/H=29-262 |
Showing 20 of 24 experimental structures (best resolution first).
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