Lactose operon repressor (lacI) is a 360-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P03023.
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The mean pLDDT of this model is 93.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 82% |
| 70 to 90 | Confident: backbone generally right | 15% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Repressor of the lactose operon. Binds allolactose as an inducer
Homotetramer
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8GOH | X-ray | 1.1 Å | A/B/C/D/E/F/G/H=336-358 |
| 1JYE | X-ray | 1.7 Å | A=1-349 |
| 2P9H | X-ray | 2.0 Å | A/B=62-330 |
| 3EDC | X-ray | 2.1 Å | A/B/C/D=1-360 |
| 1EFA | X-ray | 2.6 Å | A/B/C=1-333 |
| 1TLF | X-ray | 2.6 Å | A/B/C/D=60-360 |
| 1LBI | X-ray | 2.7 Å | A/B/C/D=1-360 |
| 4RZS | X-ray | 2.71 Å | A/B/C/D=1-360 |
| 1JYF | X-ray | 3.0 Å | A=1-349 |
| 4RZT | X-ray | 3.1 Å | A/B/C/D=1-360 |
| 1LBH | X-ray | 3.2 Å | A/B/C/D=1-360 |
| 2PAF | X-ray | 3.5 Å | A/B=62-330 |
| 2PE5 | X-ray | 3.5 Å | A/B/C=2-331 |
| 1JWL | X-ray | 4.0 Å | A/B/C=1-333 |
| 1LBG | X-ray | 4.8 Å | A/B/C/D=1-360 |
| 1CJG | NMR | A/B=1-62 | |
| 1L1M | NMR | A/B=1-62 | |
| 1LCC | NMR | A=1-51 | |
| 1LCD | NMR | A=1-51 | |
| 1LQC | NMR | A=1-56 |
Showing 20 of 25 experimental structures (best resolution first).
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