DNA-directed RNA polymerase III subunit RPC1 (RPO31) is a 1460-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P04051.
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The mean pLDDT of this model is 86.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 54% |
| 70 to 90 | Confident: backbone generally right | 40% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent…
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7Z0H | EM | 2.6 Å | A=1-1460 |
| 7Z1O | EM | 2.7 Å | A=1-1460 |
| 7Z31 | EM | 2.76 Å | A=1-1460 |
| 7Z1L | EM | 2.8 Å | A=1-1460 |
| 7Z30 | EM | 2.9 Å | A=1-1460 |
| 7Z2Z | EM | 3.07 Å | A=1-1460 |
| 8BWS | EM | 3.2 Å | A=1-1460 |
| 6TUT | EM | 3.25 Å | A=1-1460 |
| 6EU3 | EM | 3.3 Å | A=1-1460 |
| 6EU1 | EM | 3.4 Å | A=1-1460 |
| 6EU2 | EM | 3.4 Å | A=1-1460 |
| 7Z1M | EM | 3.4 Å | A=1-1460 |
| 6F40 | EM | 3.7 Å | A=1-1460 |
| 5FJ8 | EM | 3.9 Å | A=1-1460 |
| 7Z1N | EM | 3.9 Å | A=1-1460 |
| 6EU0 | EM | 4.0 Å | A=1-1460 |
| 6CNB | EM | 4.1 Å | A=1-1460 |
| 6CNC | EM | 4.1 Å | A=1-1460 |
| 6F44 | EM | 4.2 Å | A=1-1460 |
| 6F41 | EM | 4.3 Å | A=1-1460 |
Showing 20 of 25 experimental structures (best resolution first).
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