Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) is a 2477-residue protein from Gallus gallus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P07751.
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The mean pLDDT of this model is 75.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 4% |
| 70 to 90 | Confident: backbone generally right | 72% |
| 50 to 70 | Low: treat with caution | 18% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization
Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with ACP1 (By similarity)
Cytoplasm, cytoskeleton, Cytoplasm, cell cortex
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9IHA | X-ray | 1.01 Å | AAA=965-1025 |
| 9EYC | X-ray | 1.06 Å | A=965-1025 |
| 3NGP | X-ray | 1.08 Å | A=965-1025 |
| 3M0R | X-ray | 1.1 Å | A=965-1025 |
| 3M0U | X-ray | 1.1 Å | A=965-1025 |
| 1G2B | X-ray | 1.12 Å | A=960-1010 |
| 9IH7 | X-ray | 1.12 Å | A=967-1025 |
| 9EYE | X-ray | 1.13 Å | AAA=965-1025 |
| 9IH6 | X-ray | 1.31 Å | A=965-1025 |
| 9EYB | X-ray | 1.34 Å | AAA=965-1025 |
| 9EYF | X-ray | 1.34 Å | A=965-1025 |
| 5IHK | X-ray | 1.35 Å | A=965-1025 |
| 3I9Q | X-ray | 1.45 Å | A=969-1025 |
| 5IHI | X-ray | 1.45 Å | A=965-1025 |
| 1U06 | X-ray | 1.49 Å | A=965-1025 |
| 5IHN | X-ray | 1.5 Å | A=965-1025 |
| 4F17 | X-ray | 1.55 Å | A=965-1025 |
| 2F2X | X-ray | 1.6 Å | A=965-1025 |
| 3M0S | X-ray | 1.6 Å | A=969-1025 |
| 2F2W | X-ray | 1.7 Å | A=965-1025 |
Showing 20 of 62 experimental structures (best resolution first).
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