Small ribosomal subunit protein uS5 (RPS2) is a 293-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P15880.
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The mean pLDDT of this model is 80.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 62% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 17% |
What pLDDT means and how to read it
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:23636399). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:23636399). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in…
Component of the small ribosomal subunit (PubMed:23636399). Interacts with zinc finger protein ZNF277 (via zinc-finger domains); the interaction is direct; the interaction is extra-ribosomal (PubMed:30530495). Interaction with ZNF277 competes with the binding of RPS2 to protein arginine methyltransferase PRMT3 (PubMed:30530495). Interacts with PRMT3 (PubMed:27697862). Interacts with PDCD2; the…
Cytoplasm, Nucleus, nucleolus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8GLP | EM | 1.67 Å | SC=1-293 |
| 8QOI | EM | 1.9 Å | SC=1-293 |
| 9O3W | EM | 1.9 Å | SC=1-293 |
| 8YOO | EM | 2.0 Å | SC=1-293 |
| 9C3H | EM | 2.0 Å | SC=1-293 |
| 7R4X | EM | 2.15 Å | C=1-293 |
| 9I2D | EM | 2.19 Å | SC=1-293 |
| 9PBE | EM | 2.19 Å | SC=59-280 |
| 8YOP | EM | 2.2 Å | SC=1-293 |
| 9O3Y | EM | 2.2 Å | SC=1-293 |
| 8JDK | EM | 2.26 Å | z=1-293 |
| 8G5Y | EM | 2.29 Å | SC=1-293 |
| 9S3D | EM | 2.32 Å | SC=1-293 |
| 9RPV | EM | 2.35 Å | RC/SC=1-293 |
| 9S3B | EM | 2.38 Å | SC=1-293 |
| 8K2C | EM | 2.4 Å | SC=1-293 |
| 8XSX | EM | 2.4 Å | SC=1-293 |
| 9SPF | EM | 2.4 Å | SC=1-293 |
| 9SPI | EM | 2.4 Å | SC=1-293 |
| 8JDL | EM | 2.42 Å | z=1-293 |
Showing 20 of 184 experimental structures (best resolution first).
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