P32797: Cell division control protein 13 (CDC13)

Cell division control protein 13 (CDC13) is a 924-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P32797.

Gene
CDC13
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
924 residues
Mean pLDDT
68.4
Model
AF-P32797-F1 v6
Model created
1 Aug 2025
PDB structures
7

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Model confidence (pLDDT)

The mean pLDDT of this model is 68.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate16%
70 to 90Confident: backbone generally right45%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions28%

What pLDDT means and how to read it

Function

Single-stranded telomeric DNA-binding protein that regulates telomere replication. Has a role in both positive and negative regulation. Promotes [TG(1-3)] strand lengthening via interaction with EST1. Promotes [C(1-3)A] strand re-synthesis by DNA polymerase alpha via interaction with POL1. Negatively regulates telomere elongation of the G strand via binding with STN1 thereby inhibiting telomerase activity

Subunit structure

Interacts with POL1, EST1, FUN12, STM1, STN1 and TEN1

Subcellular location

Chromosome, telomere

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4HCEX-ray2.3 ÅA/B=344-495
3OIQX-ray2.4 ÅA=12-243
3NWSX-ray2.5 ÅA/B/C/D=13-227
3OIPX-ray2.5 ÅA=12-243
3NWTX-ray2.7 ÅA=13-227
1KXLNMRA=496-694
1S40NMRA=496-694

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