Protein THO1 (THO1) is a 218-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P40040.
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The mean pLDDT of this model is 71.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 43% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 27% |
| Below 50 | Very low: often disordered regions | 26% |
What pLDDT means and how to read it
Facilitates RNA binding of SUB2 and likely plays a role in mRNA export (PubMed:37578863). Suppressor of the transcriptional defect of HPR1 by overexpression
Interacts with SUB2 in the presence of RNA; this interaction facilitates RNA binding of SUB2
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8ENK | X-ray | 2.5 Å | E=123-178 |
| 1H1J | NMR | S=2-50 | |
| 2WQG | NMR | A=2-50 | |
| 4UZW | NMR | A=2-50 | |
| 4UZX | NMR | A=119-183 |
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