Transcription initiation factor IIF subunit beta (TFG2) is a 400-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P41896.
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The mean pLDDT of this model is 67.2 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 7% |
| 70 to 90 | Confident: backbone generally right | 43% |
| 50 to 70 | Low: treat with caution | 28% |
| Below 50 | Very low: often disordered regions | 23% |
What pLDDT means and how to read it
TFIIF is a general transcription initiation factor that binds to RNA polymerase II. Its functions include the recruitment of RNA polymerase II to the promoter bound DNA-TBP-TFIIB complex, decreasing the affinity of RNA polymerase II for non-specific DNA, allowing for the subsequent recruitment of TFIIE and TFIIH, and facilitating RNA polymerase II elongation
TFIIF is composed of three different subunits: TFG1/RAP74, TFG2/RAP30 and TAF14
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7O4J | EM | 2.9 Å | R=1-400 |
| 7ML0 | EM | 3.0 Å | R=1-400 |
| 8CEN | EM | 3.0 Å | R=1-400 |
| 7ML4 | EM | 3.1 Å | R=1-400 |
| 7ZS9 | EM | 3.1 Å | R=1-400 |
| 7O4I | EM | 3.2 Å | R=1-400 |
| 7O75 | EM | 3.2 Å | R=1-400 |
| 7UI9 | EM | 3.3 Å | Q=1-400 |
| 7UIO | EM | 3.3 Å | AQ/BQ=1-400 |
| 7ML2 | EM | 3.4 Å | R=1-400 |
| 7O72 | EM | 3.4 Å | R=1-400 |
| 7O73 | EM | 3.4 Å | R=1-400 |
| 7MEI | EM | 3.54 Å | M=1-400 |
| 7MK9 | EM | 3.54 Å | M=1-400 |
| 8CEO | EM | 3.6 Å | R=1-400 |
| 8UMI | EM | 3.7 Å | P=1-400 |
| 8UOT | EM | 3.7 Å | P=1-400 |
| 8UOQ | EM | 3.8 Å | P=1-400 |
| 7ML1 | EM | 4.0 Å | R=1-400 |
| 7ZSA | EM | 4.0 Å | R=1-400 |
Showing 20 of 34 experimental structures (best resolution first).
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