Small nuclear ribonucleoprotein E (SNRPE) is a 92-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P62304.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 90.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 83% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 11% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23246290, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:32494006). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077). As part of the U7 snRNP it is involved in histone…
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:19325628, PubMed:21516107, PubMed:23246290, PubMed:25555158, PubMed:26912367, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:32494006, PubMed:36797247). Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB,…
Cytoplasm, cytosol, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4F7U | X-ray | 1.9 Å | E/H=1-92 |
| 5XJL | X-ray | 2.5 Å | E=1-92 |
| 7EVO | EM | 2.5 Å | c=1-92 |
| 5XJU | X-ray | 2.58 Å | E=1-92 |
| 8H6L | EM | 2.6 Å | 2e/4e/5e=1-92 |
| 8H6K | EM | 2.7 Å | 2e/4e/5e=1-92 |
| 8HK1 | EM | 2.7 Å | c=1-92 |
| 8C6J | EM | 2.8 Å | e/p=1-92 |
| 9NH5 | EM | 2.82 Å | E=1-92 |
| 9NH6 | EM | 2.82 Å | E=1-92 |
| 6ID1 | EM | 2.86 Å | e/l=1-92 |
| 7DVQ | EM | 2.89 Å | e/l=1-92 |
| 6ID0 | EM | 2.9 Å | e/l=1-92 |
| 5XJT | X-ray | 2.92 Å | E=1-92 |
| 6QW6 | EM | 2.92 Å | 4e/5e=1-92 |
| 6ICZ | EM | 3.0 Å | e/l=1-92 |
| 7VPX | EM | 3.0 Å | c/l=1-92 |
| 8I0R | EM | 3.0 Å | e/j=1-92 |
| 8I0T | EM | 3.0 Å | e/j=1-92 |
| 8I0V | EM | 3.0 Å | e/j=1-92 |
Showing 20 of 83 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.