Calcineurin subunit B type 1 (PPP3R1) is a 170-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P63098.
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The mean pLDDT of this model is 91.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 81% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity
Forms a complex composed of a calmodulin-dependent catalytic subunit (also known as calcineurin A) and a regulatory Ca(2+)-binding subunit (also known as calcineurin B) (PubMed:12218175, PubMed:12357034, PubMed:17498738, PubMed:22343722, PubMed:23468591, PubMed:26794871, PubMed:27974827, PubMed:8524402). There are three catalytic subunits, each encoded by a separate gene (PPP3CA, PPP3CB, and…
Cytoplasm, cytosol, Cell membrane, Cell membrane, sarcolemma
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4F0Z | X-ray | 1.7 Å | B=1-170 |
| 6NUC | X-ray | 1.9 Å | B=16-170 |
| 6NUF | X-ray | 1.9 Å | B=16-170 |
| 3LL8 | X-ray | 2.0 Å | B/D=16-170 |
| 9NXE | X-ray | 2.09 Å | B=16-170 |
| 1AUI | X-ray | 2.1 Å | B=2-170 |
| 9NXN | X-ray | 2.1 Å | B=1-170 |
| 4OR9 | X-ray | 2.23 Å | B=1-170 |
| 2P6B | X-ray | 2.3 Å | B/D=15-170 |
| 6NUU | X-ray | 2.3 Å | B=16-170 |
| 7U0T | X-ray | 2.45 Å | A=3-170 |
| 5SVE | X-ray | 2.6 Å | B=1-170 |
| 4ORC | X-ray | 2.7 Å | B=1-170 |
| 4ORA | X-ray | 2.75 Å | B=1-170 |
| 1M63 | X-ray | 2.8 Å | B/F=2-170 |
| 1MF8 | X-ray | 3.1 Å | B=1-170 |
| 9NXF | X-ray | 3.13 Å | B/E=16-170 |
| 9CHU | EM | 3.49 Å | A=16-170 |
| 9B9G | EM | 3.5 Å | H/J=1-170 |
| 9CHX | EM | 3.5 Å | A=16-170 |
Showing 20 of 21 experimental structures (best resolution first).
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