Sulfiredoxin-1 (SRXN1) is a 137-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9BYN0.
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The mean pLDDT of this model is 83.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 70% |
| 70 to 90 | Confident: backbone generally right | 7% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 18% |
What pLDDT means and how to read it
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4 (PubMed:15448164, PubMed:15590625). Does not act on PRDX5 or PRDX6 (PubMed:15448164, PubMed:15590625). May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (PubMed:15448164, PubMed:15590625)
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1XW3 | X-ray | 1.65 Å | A=32-137 |
| 3CYI | X-ray | 1.8 Å | A=32-137 |
| 1XW4 | X-ray | 2.0 Å | X=32-137 |
| 3HY2 | X-ray | 2.1 Å | X/Y=32-137 |
| 2RII | X-ray | 2.6 Å | X/Y=32-137 |
| 7LJ1 | X-ray | 2.97 Å | a/b/c/d/e/f/g/h/i/j/k/l/m/n/o/p/q/r/s/t=32-137 |
| 1YZS | NMR | A=17-137 | |
| 2B6F | NMR | A=17-137 |
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