Ubiquitin-like protein 5 (UBL5) is a 73-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9BZL1.
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The mean pLDDT of this model is 91.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 78% |
| 70 to 90 | Confident: backbone generally right | 22% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins (PubMed:25092792). Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers (PubMed:25862789). Also plays a protective role against ER stress-induced apoptosis (PubMed:37315790)
Interacts with CLK1, CLK3 and CLK4. Interacts with coilin/COIL (PubMed:23726919). Interacts with spliceosome components SART1 and EFTUD2 (PubMed:25092792). Interacts with FANCI; this interaction promotes FANCI dimerization (PubMed:25862789)
Cytoplasm, Nucleus, Nucleus, Cajal body
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4PYU | X-ray | 2.0 Å | A/B/G/K/O/S=1-73 |
| 8H6K | EM | 2.7 Å | 4M=1-73 |
| 8Q7N | EM | 3.1 Å | s=1-73 |
| 6AHD | EM | 3.8 Å | A0=1-73 |
| 7ABF | EM | 3.9 Å | q=1-73 |
| 7AAV | EM | 4.2 Å | q=1-73 |
| 8QO9 | EM | 5.29 Å | s=1-73 |
| 7ABG | EM | 7.8 Å | q=1-73 |
| 7ABI | EM | 8.0 Å | q=1-73 |
| 1P0R | NMR | A=1-73 |
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