1AO6: Human serum albumin

Crystal structure of human serum albumin. Determined by X-ray diffraction at 2.5 Å resolution. Released 27 May 1998.

Method

X-ray diffraction

Resolution

2.5 Å

Organism

Homo sapiens

Chains

2

Atoms

9,205

Mol. weight

133.14 kDa

Released

27 May 1998

Explore 1AO6 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1AO6 contains 74 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 38 helices, 0 β-strands

Molecules and chains

>1AO6_1 SERUM ALBUMIN (chains A, B)
DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAE
NCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEV
DVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLP
KLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTK
VHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPA
DLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKC
CAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVST
PTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES
LVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKAT
KEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

Primary citation

Crystal structure of human serum albumin at 2.5 A resolution. Sugio, S., Kashima, A., Mochizuki, S. et al. Protein Eng (1999) 12:439-446. DOI 10.1093/protein/12.6.439 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P02768 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 9IK6 1.69 Å, Human Serum Albumin crystallized with T4, pH 6.5
• 6YG9 1.89 Å, Crystal structure of human serum albumin (HSA) in complex with gn-07.
• 1N5U 1.9 Å, X-ray study of human serum albumin complexed with heme
• 8RCO 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid II at 1.9 A resolution
• 8RCP 1.9 Å, Structure of Human Serum Albumin in complex with Myristic Acid
• 8RGK 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid at 1.9 A resolution
• 8RGL 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid I at 1.9 A resolution…
• 9EOD 1.9 Å, Human serum albumin with adamantene carboxylic acid
• 9CSG 1.91 Å, Human Serum Albumin Bound to Cerastecin Compound 5e
• 6QIO 1.95 Å, Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the…
• 9IK7 1.97 Å, Human Serum Albumin crystallized with T4, pH 7.5
• 7VR0 1.98 Å, Human Serum Albumin

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